Description and study of the steroid Metabolome in mucinous ovarian cancer
This research aims to discover better ways to diagnose and track a very rare type of cancer called mucinous ovarian cancer. Doctors need new tools to understand how patients are responding to treatment. The study is investigating if urine tests can be useful by looking for certain substances. There are three main groups of participants: women with ovarian cysts, women who have had mucinous ovarian cancer and finished treatment, and women with certain bowel cancers. Researchers believe that the information gathered could lead to new tests and treatments for ovarian cancer, potentially helping patients in the future. The study involves collecting urine samples at home and at the hospital.
نظرة سريعة
ما هو موضوع هذه الدراسة؟
This research project is all about finding new and better ways to understand and diagnose a very rare type of cancer called mucinous ovarian cancer. Currently, it can be quite tricky for doctors to find out exactly where some of these cancers come from, and to know how well treatments are working for patients.
The main idea behind this study is to see if we can use simple urine tests to help. The researchers are looking for special substances in urine that might act as clues for diagnosing the cancer and checking its progress. By studying these substances, they hope to develop new tests that could be really helpful for people with ovarian cancer. They are also comparing results from ovarian cancer patients with those who have certain types of bowel cancer to learn more.
The study is divided into three main groups. One group includes women who are having surgery for growths on their ovaries. Another group involves women who have already been treated for mucinous ovarian cancer, and the third group focuses on women with certain types of bowel cancer. The goal is to collect different types of information and urine samples from these groups to get a complete picture. The ultimate aim is that this research could lead to new tools that doctors can use to diagnose and monitor ovarian cancer more effectively, which would be fantastic for future patients.
النقاط الرئيسية
- Aims to find new ways to diagnose and monitor a rare type of ovarian cancer.
- Investigates if urine tests can identify specific substances linked to the cancer.
- Involves collecting urine samples at home over a 24-hour period.
- Could lead to future diagnostic tests or treatments for ovarian cancer.
- Participation may involve one or several urine collections over two years.
- Strict measures are in place to protect your personal information.
من قد يكون مؤهلاً؟
This study is open to women aged 18 or over. It's important that you understand the study and agree to take part. There are three different parts, and who can join depends on your current health situation.
For the first part, you might be eligible if you are having surgery for a growth on your ovary, or if you have recently been diagnosed with mucinous ovarian cancer and haven't started treatment yet. For the second part, you might be able to join if you have finished your first round of treatment for mucinous ovarian cancer.
Finally, for the third part, you could be eligible if you have a condition called pseudomyxoma peritonei or certain types of appendiceal (bowel) cancers. There are also specific reasons why you might not be able to join, such as if you've recently used hormonal contraception, hormone replacement therapy, or steroid treatments.
هل يمكن أن تناسبك هذه الدراسة؟
أجب عن هذه الأسئلة السريعة لترى ما إذا كنت مؤهلاً. هذا دليل فقط - الفريق البحثي هو الذي يتخذ القرار النهائي.
- Are you a woman aged 18 or older?
- هل يمكنك فهم معلومات الدراسة وتقديم موافقتك؟
- Have you been diagnosed with mucinous ovarian cancer, or are you having surgery for an ovarian mass?
- Do you have a diagnosis of pseudomyxoma peritonei or certain types of appendiceal cancer?
- Have you avoided hormonal contraception, HRT, or steroid treatments in the last three months (this might apply to some parts of the study)?
- Have you not started chemotherapy for ovarian cancer yet (if joining the diagnostic part)?
ماذا يتضمن المشاركة؟
If you decide to take part, you'll first receive a detailed information sheet about the study, and everything will be explained clearly. If you're happy to go ahead, you'll sign a consent form. Then, you'll answer some questions about yourself and your health.
The main thing you'll be asked to do is collect all your urine over a 24-hour period, in your own home, at a time that suits you. You'll be given a special bottle for this. This urine sample will then be collected when you next visit the hospital.
If you're in the first or third part of the study, you'll only need to do this urine collection once. If you're in the second part of the study, you'll be asked to collect urine about every three months for two years. The researchers will try to arrange these collections to fit in with your regular hospital appointments, so it should be as convenient as possible.
المخاطر والفوائد المحتملة
المواقع (10)
- مؤسسة مستشفيات جامعة برمنغهام التابعة لهيئة الخدمات الصحية الوطنيةالمدينة فقطبرمنغهام، إنجلترا
- Cardiff ECMCالمدينة فقطكارديف، ويلز
- Hinchingbrooke Hospital (hinchingbrooke Healthcare Trust)المدينة فقطHuntingdon, England
- Nottingham University Hospitals NHS Trust - Queen's Medical Centre Campusالمدينة فقطنوتنغهام، إنجلترا
- The Christie at Homeالمدينة فقطمانشستر، إنجلترا
- مستشفيات جامعة ساسكس التابعة لمؤسسة الخدمات الصحية الوطنيةالمدينة فقطWorthing, England
- The Guys and Lewisham NHS Trustالمدينة فقطلندن، إنجلترا
- Hammersmith Hospitals NHS Trustالمدينة فقطلندن، إنجلترا
- مستشفيات جامعة شمال ميدلاندز التابعة لخدمة الصحة الوطنيةالمدينة فقطStoke-on-trent, England
- Sandwell and West Birmingham Hospitals NHS Trustالمدينة فقطSmethwick, England
أسئلة شائعة
What is mucinous ovarian cancer?
It's a very rare type of cancer that starts in the ovaries. This study is trying to find better ways to diagnose and monitor it.
Why do I need to collect urine?
Researchers are looking for specific substances (called 'biomarkers') in your urine that might help diagnose the cancer or show how treatment is working.
هل سأحصل على نتائج اختباري؟
The study aims to gather overall information, not to provide individual test results that would affect your personal medical care.
كم ستستغرق الدراسة بالنسبة لي؟
It depends on which part of the study you join. Some people collect urine once, while others do so every three months for up to two years, usually during their regular appointments.
من الذي يمول هذا البحث؟
The study is funded by The Eve Appeal and the Birmingham Women’s and Children’s Hospital Global Research Fund.
كيفية معرفة المزيد
Rachel Iles
تحدث دائمًا إلى طبيبك العام أو الأخصائي قبل اتخاذ قرار بالمشاركة في دراسة.
هل أنت مهتم بالمشاركة؟
نقاش
مناقشة المجتمع
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