Can I take Co-codamol and Clopidogrel together?

لماذا يحدث هذا

Clopidogrel needs to be broken down by the body to start working. Codeine (in co-codamol) can slow down the movement of your gut and interfere with how clopidogrel is absorbed and processed, meaning there is less of the active medicine in your bloodstream to thin your blood.

You should speak to your doctor or pharmacist before taking these together. They may suggest an alternative painkiller that does not interfere with your heart medication, such as paracetamol on its own. If you must take both, your doctor may need to monitor you more closely.

Paracetamol overdose

Co-codamol contains paracetamol. Do not take it with any other paracetamol-containing products (such as cold and flu remedies), as this can lead to fatal liver damage.

Opioid addiction and withdrawal

Co-codamol contains codeine, which can cause addiction if used for more than 3 days. Stopping suddenly after long-term use can cause withdrawal symptoms.

صعوبات في التنفس

Do not take co-codamol if you have severe asthma or breathing problems, as the codeine can dangerously slow your breathing.

Active bleeding

Do not take clopidogrel if you have an active bleeding site, such as a stomach ulcer or bleeding in the brain, as it prevents blood clotting and will worsen the condition.

Upcoming surgery or dental work

You must tell your surgeon or dentist you are taking clopidogrel at least 7 days before any planned procedure, as it increases your risk of bleeding and may need to be stopped temporarily.

الكحول

You must avoid drinking alcohol while taking co-codamol. Combining alcohol with codeine increases the risk of serious side effects, such as extreme sleepiness, breathing difficulties, and loss of consciousness. Additionally, both alcohol and paracetamol can affect the liver; combining them regularly increases the risk of liver damage.

It is best to avoid or strictly limit alcohol while taking clopidogrel. Both alcohol and clopidogrel can irritate the stomach lining and increase the risk of internal bleeding, particularly in the stomach and intestines.

عصير الجريب فروت

Grapefruit juice can interfere with how your body processes codeine, potentially making the medicine less effective or increasing the risk of side effects. It is best to avoid grapefruit juice while taking this medicine.

Grapefruit juice can reduce the effectiveness of clopidogrel, making it less likely to prevent blood clots. It is best to avoid drinking grapefruit juice or eating grapefruit while taking this medicine.

الكافيين

Some versions of co-codamol already contain caffeine. If you consume extra caffeine from coffee, tea, or energy drinks, it may make you feel shaky, anxious, or cause a racing heart.

Taking multiple medicines? Our مدقق تفاعلات الأدوية helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

إخلاء المسؤولية

هذه المعلومات لأغراض تعليمية عامة فقط ولا ينبغي الاعتماد عليها كبديل للنصيحة الطبية المهنية. استشر دائمًا طبيبك العام أو الصيدلي أو أي متخصص رعاية صحية مؤهل آخر قبل اتخاذ قرارات بشأن أدويتك. قد تختلف الظروف الفردية، ولا يمكن إلا لمتخصص الرعاية الصحية الذي يعرف تاريخك الطبي تقديم إرشادات مخصصة.