CDAN1 interacting nuclease 1
آخر تحديث 4 مارس 2025
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The CDIN1 gene provides instructions for making a protein called the CDAN1-interacting nuclease 1. This protein likely acts as a nuclease. Nucleases cut (cleave) building blocks called nucleotides one at a time from DNA and its chemical cousin RNA. CDAN1-interacting nuclease 1 is thought to play a role in correcting errors (DNA repair) that are made when DNA is copied (DNA replication) in preparation for cell division. This protein is also involved in the growth and development of red blood cells (erythropoiesis).
Normal function
The CDIN1 gene provides instructions for making a protein called the CDAN1-interacting nuclease 1. This protein likely acts as a nuclease. Nucleases cut (cleave) building blocks called nucleotides one at a time from DNA and its chemical cousin RNA. CDAN1-interacting nuclease 1 is thought to play a role in correcting errors (DNA repair) that are made when DNA is copied (DNA replication) in preparation for cell division. This protein is also involved in the growth and development of red blood cells (erythropoiesis).
Conditions referring to this gene or chromosome
Other names
C15orf41
HH114
Related patient information and medicines
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قراءة إضافية ومراجع
- CDAN1 interacting nuclease 1; MedlinePlus, National Library of Medicine.
- Iolascon A, Andolfo I, Russo R. Congenital dyserythropoietic anemias. Blood. 2020 Sep 10;136(11):1274-1283. doi: 10.1182/blood.2019000948.
- Mendez M, Moreno-Carralero MI, Peri VL, Camacho-Galan R, Bosch-Benitez JM, Huerta-Aragones J, Sanchez-Calero-Guilarte J, Moreno-Risco MB, Alonso-Dominguez JM, Moran-Jimenez MJ. Congenital dyserythropoietic anemia types Ib, II, and III: novel variants in the CDIN1 gene and functional study of a novel variant in the KIF23 gene. Ann Hematol. 2021 Feb;100(2):353-364. doi: 10.1007/s00277-020-04319-5. Epub 2020 Nov 7.
- Russo R, Iolascon A, Andolfo I, Marra R, Rosato BE. Updates on clinical and laboratory aspects of hereditary dyserythropoietic anemias. Int J Lab Hematol. 2024 Aug;46(4):595-605. doi: 10.1111/ijlh.14307. Epub 2024 May 15.
- Tamary H, Dgany O. Congenital Dyserythropoietic Anemia Type I. 2009 Apr 21 [updated 2021 Jul 29]. In: Adam MP, Bick S, Mirzaa GM, Wallace SE, Amemiya A, editors. GeneReviews(R) [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2026. Available from http://www.ncbi.nlm.nih.gov/books/NBK5313/
تاريخ المقال
المقال متاح أيضًا باللغة الإنجليزية, الألمانية, إسبانية, الفرنسية, إيطالي, البرتغالية, الهندية, العبرية, العربية ,، و السويدية.
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