ETS variant transcription factor 6
آخر تحديث 5 Jul 2022
يتوافق مع الإرشادات التحريرية
- تنزيلتنزيل
- مشاركة
- Language
- نقاش
- نسخة صوتية
- أضف إلى المصادر المفضلة على جوجل
ال ETV6 gene provides instructions for producing a protein that functions as a transcription factor, which means that it attaches (binds) to specific regions of DNA and controls the activity of certain genes. The ETV6 protein is found in the nucleus of cells throughout the body, where it turns off (represses) gene activity. It plays a key role in development before birth and in regulating blood cell formation.
Normal function
ال ETV6 gene provides instructions for producing a protein that functions as a transcription factor, which means that it attaches (binds) to specific regions of DNA and controls the activity of certain genes. The ETV6 protein is found in the nucleus of cells throughout the body, where it turns off (represses) gene activity. It plays a key role in development before birth and in regulating blood cell formation.
Conditions referring to this gene or chromosome
Other names
ETS translocation variant 6
ets variant 6
ets variant gene 6 (TEL oncogene)
ETS-related protein Tel1
ETV6_HUMAN
TEL
TEL1 oncogene
transcription factor ETV6
Related patient information and medicines
Patient information leaflet
ابيضاض الدم الليمفاوي الحاد
Acute lymphoblastic leukaemia (ALL) is a condition where the bone marrow makes large numbers of abnormal immature lymphocytes. The immature cells are called lymphoblasts. There are various subtypes of ALL. For example, the abnormal lymphoblasts can be immature B or T lymphocytes. The abnormal lymphoblasts continue to divide and multiply but do not.
Patient information leaflet
حقائق عن سرطان الثدي وعوامل الخطر
Most cases of breast cancer occur by chance. However, breast cancer does occur more often than usual in some families because of their genetic makeup. Most cases of breast cancer occur by chance. However, breast cancer does occur more often than usual in some families because of their genetic makeup. Genetic means that the condition is passed on.
Patient information leaflet
التهاب الكبد المناعي الذاتي
However, with treatment, the outlook for people with this condition is very good. Treatment is usually with steroids and other medicines which suppress inflammation. What is autoimmune hepatitis. There are many causes of hepatitis. For example, alcohol excess and various viral infections are the common causes of hepatitis. Please read the separate.
Patient information leaflet
الهيموفيليا
الهيموفيليا is a rare bleeding disorder that affects your ability to make a clot. The blood contains substances called clotting factors that work with platelets to form a clot. When you injure yourself the clot stops you bleeding. Haemophilia is a condition where there is a deficiency of clotting factors, so people with this condition usually have.
Patient information leaflet
كوفيد-19
This leaflet deals with the symptoms, causes and treatment of COVID-19. What is COVID-19. كوفيد-19 هو an infectious disease caused by a virus (SARS CoV-2). COVID-19 is short for "coronavirus disease 2019", because the disease was first identified in December 2019. However, in some cases, they also seem to be less likely to cause serious illness..
Patient information leaflet
التهاب الفقار المقسط
التهاب الفقار المقسط is a chronic inflammatory arthritis. It mainly affects the lower back but can affect the rest of the spine. Ankylosing spondylitis ... It is not known exactly why ankylosing spondylitis occurs but there is a genetic predisposition. 6 out of 100 people who have a particular gene variant called HLA-B27 have ankylosing.
قراءة إضافية ومراجع
- ETS variant transcription factor 6; MedlinePlus, National Library of Medicine.
- Haferlach C, Bacher U, Schnittger S, Alpermann T, Zenger M, Kern W, Haferlach T. ETV6 rearrangements are recurrent in myeloid malignancies and are frequently associated with other genetic events. Genes Chromosomes Cancer. 2012 Apr;51(4):328-37. doi: 10.1002/gcc.21918. Epub 2011 Dec 8.
- Murati A, Brecqueville M, Devillier R, Mozziconacci MJ, Gelsi-Boyer V, Birnbaum D. Myeloid malignancies: mutations, models and management. BMC Cancer. 2012 Jul 23;12:304. doi: 10.1186/1471-2407-12-304.
- Zhou MH, Gao L, Jing Y, Xu YY, Ding Y, Wang N, Wang W, Li MY, Han XP, Sun JZ, Wang LL, Yu L. Detection of ETV6 gene rearrangements in adult acute lymphoblastic leukemia. Ann Hematol. 2012 Aug;91(8):1235-43. doi: 10.1007/s00277-012-1431-4. Epub 2012 Feb 29.
تاريخ المقال
المقال متاح أيضًا باللغة الإنجليزية, الألمانية, إسبانية, الفرنسية, إيطالي, البرتغالية, الهندية, العبرية, العربية ,، و السويدية.
5 Jul 2022 | أحدث إصدار
1 Feb 2013 | نُشر في الأصل
انضم إلى المحادثة
شارك أفكارك أو تجاربك مع الآخرين في مجتمعات المرضى.
اسأل، شارك، تواصل.
تصفح المناقشات، اطرح الأسئلة، وشارك التجارب عبر مئات المواضيع الصحية.
اشترك في النشرة الإخبارية للمرضى
جرعتك الأسبوعية من النصائح الصحية الواضحة والموثوقة - مكتوبة لمساعدتك على الشعور بالاطلاع والثقة والتحكم.
من خلال الاشتراك، فإنك تقبل سياسة الخصوصية. يمكنك إلغاء الاشتراك في أي وقت. نحن لا نبيع بياناتك أبدًا.