fibroblast growth factor 10
آخر تحديث 18 Aug 2020
يتوافق مع الإرشادات التحريرية
- تنزيلتنزيل
- مشاركة
- Language
- نقاش
- نسخة صوتية
- أضف إلى المصادر المفضلة على جوجل
ال FGF10 gene provides instructions for making a protein called fibroblast growth factor 10 (FGF10). This protein is part of a family of proteins called fibroblast growth factors that are involved in important processes such as cell division, regulation of cell growth and maturation, formation of blood vessels, wound healing, and development before birth. By attaching to another protein known as a receptor, the FGF10 protein triggers a cascade of chemical reactions inside the cell that signals the cell to undergo certain changes, such as maturing to take on specialized functions. During development before birth, the signals triggered by the FGF10 protein appear to stimulate cells to form the structures that make up the ears, skeleton, organs, and glands in the eyes and mouth.
Normal function
ال FGF10 gene provides instructions for making a protein called fibroblast growth factor 10 (FGF10). This protein is part of a family of proteins called fibroblast growth factors that are involved in important processes such as cell division, regulation of cell growth and maturation, formation of blood vessels, wound healing, and development before birth. By attaching to another protein known as a receptor, the FGF10 protein triggers a cascade of chemical reactions inside the cell that signals the cell to undergo certain changes, such as maturing to take on specialized functions. During development before birth, the signals triggered by the FGF10 protein appear to stimulate cells to form the structures that make up the ears, skeleton, organs, and glands in the eyes and mouth.
Conditions referring to this gene or chromosome
Other names
FGF-10
FGF10_HUMAN
keratinocyte growth factor 2
Related patient information and medicines
Patient information leaflet
تصلب الجلد الموضعي
Localised scleroderma causes one or more patches of hard skin. There are different types. Generalised morphoea symptoms This is a ... Causes of localised scleroderma The cause is not clear. What is known is that cells called fibroblasts make too much of a protein called collagen. The collagen gets deposited in the skin, causing scarring and.
Patient information leaflet
انسداد الوريد الشبكي
انسداد الوريد الشبكي occurs when one of the tiny veins in the retina becomes blocked by a blood clot. What is retinal vein occlusion. Retinal vein occlusion is a fairly common cause of loss of vision in the UK. A number of diff... The earlier this is done, the better the chance of some recovery: Anti-vascular endothelial growth factor.
Patient information leaflet
التهاب الجيوب الأنفية المزمن
Other medical conditions Sometimes, chronic sinusitis can develop as a result of another medical condition. Examples include: Cystic fibrosis , a genetic condition which causes thick mucus that is difficult to clear from the lungs, sinuses, and elsewhere. Granulomatosis with polyangiitis , a rare condition causing inflammation of blood vessels..
Patient information leaflet
اعتلال الشبكية السكري
المرحلة 3: proliferative retinopathy Proliferative retinopathy is the advanced diabetic retinopathy that occurs when damaged blood vessels in the retina make chemicals called growth factors. Eye checks for diabetic retinopathy NICE guidance on فحص and referral for diabetic eye problems The National Institute for Health and Care Excellence.
Patient information leaflet
سرطان الثدي
Breast cancer is the most common cancer in women. Most cases occur in women over the age of 50 but breast cancer can occur in younger women. If breast cancer is diagnosed at an early stage, less treatment may be needed and it is more likely to be effective. In general, the more advanced the cancer (the more it has grown and spread), the less.
Patient information leaflet
سرطان الحنجرة
سرطان الحنجرة is just one type of cancer that can occur in. Throat cancers and cancers that affect the mouth, are together all called oropharyngeal cancers. How common is throat cancer. Throat (laryngeal) cancer is uncommon in the UK with around 2,000 cases developing each year. It is twice as common in men as in women. Although it is.
قراءة إضافية ومراجع
- fibroblast growth factor 10; MedlinePlus, National Library of Medicine.
- Milunsky JM, Zhao G, Maher TA, Colby R, Everman DB. LADD syndrome is caused by FGF10 mutations. Clin Genet. 2006 Apr;69(4):349-54. doi: 10.1111/j.1399-0004.2006.00597.x.
- Rohmann E, Brunner HG, Kayserili H, Uyguner O, Nurnberg G, Lew ED, Dobbie A, Eswarakumar VP, Uzumcu A, Ulubil-Emeroglu M, Leroy JG, Li Y, Becker C, Lehnerdt K, Cremers CW, Yuksel-Apak M, Nurnberg P, Kubisch C, Schlessinger J, van Bokhoven H, Wollnik B. Mutations in different components of FGF signaling in LADD syndrome. Nat Genet. 2006 Apr;38(4):414-7. doi: 10.1038/ng1757. Epub 2006 Feb 26.
- Shams I, Rohmann E, Eswarakumar VP, Lew ED, Yuzawa S, Wollnik B, Schlessinger J, Lax I. Lacrimo-auriculo-dento-digital syndrome is caused by reduced activity of the fibroblast growth factor 10 (FGF10)-FGF receptor 2 signaling pathway. Mol Cell Biol. 2007 Oct;27(19):6903-12. doi: 10.1128/MCB.00544-07. Epub 2007 Aug 6.
تاريخ المقال
المقال متاح أيضًا باللغة الإنجليزية, الألمانية, إسبانية, الفرنسية, إيطالي, البرتغالية, الهندية, العبرية, العربية ,، و السويدية.
18 Aug 2020 | أحدث إصدار
1 Jun 2013 | نُشر في الأصل
انضم إلى المحادثة
شارك أفكارك أو تجاربك مع الآخرين في مجتمعات المرضى.
اسأل، شارك، تواصل.
تصفح المناقشات، اطرح الأسئلة، وشارك التجارب عبر مئات المواضيع الصحية.
اشترك في النشرة الإخبارية للمرضى
جرعتك الأسبوعية من النصائح الصحية الواضحة والموثوقة - مكتوبة لمساعدتك على الشعور بالاطلاع والثقة والتحكم.
من خلال الاشتراك، فإنك تقبل سياسة الخصوصية. يمكنك إلغاء الاشتراك في أي وقت. نحن لا نبيع بياناتك أبدًا.