transforming growth factor beta induced
آخر تحديث 18 Aug 2020
يتوافق مع الإرشادات التحريرية
- تنزيلتنزيل
- مشاركة
- Language
- نقاش
- نسخة صوتية
- أضف إلى المصادر المفضلة على جوجل
ال TGFBI gene provides instructions for making a protein called transforming growth factor beta induced (TGFBI). This protein is released (secreted) from cells and becomes part of the extracellular matrix, which is an intricate network that forms in the spaces between cells and provides structural support to tissues. The TGFBI protein is thought to play a role in the attachment of cells to one another (cell adhesion) and cell movement (migration). This protein is found in many tissues in the body, including the the clear, outer covering of the eye (the cornea).
Normal function
ال TGFBI gene provides instructions for making a protein called transforming growth factor beta induced (TGFBI). This protein is released (secreted) from cells and becomes part of the extracellular matrix, which is an intricate network that forms in the spaces between cells and provides structural support to tissues. The TGFBI protein is thought to play a role in the attachment of cells to one another (cell adhesion) and cell movement (migration). This protein is found in many tissues in the body, including the the clear, outer covering of the eye (the cornea).
Conditions referring to this gene or chromosome
Other names
beta ig-h3
BGH3_HUMAN
BIGH3
CDB1
CDG2
CDGG1
CSD
CSD1
CSD2
CSD3
EBMD
kerato-epithelin
LCD1
RGD-CAP
RGD-containing collagen-associated protein
transforming growth factor, beta-induced, 68kDa
transforming growth factor-beta-induced protein ig-h3
Related patient information and medicines
Patient information leaflet
ارتفاع ضغط الدم أثناء الحمل
What is high blood pressure in pregnancy. If you have high bl... Medicine to lower the blood pressure may be prescribed for a while. The most commonly used medicine هو labetalol. This may allow your pregnancy to progress further before delivering your baby. The best time to induce the birth (or deliver by caesarean section) varies depending on the.
Patient information leaflet
الثلاسيميا
Thalassaemia is an inherited condition affecting the blood. Thalassaemia is an inherited (genetic) condition affecting the blood. Haemoglobin is made out of different parts. The main parts are called alpha chains and beta chains which are put together to make the haemoglobin molecule. In thalassaemia, part of the haemoglobin is faulty - usually.
Patient information leaflet
ضخامة الأطراف
ضخامة الأطراف is a rare, progressive condition in which you make too much growth hormone. This causes a range of symptoms that develop gradually, often over several years. The most noticeable symptoms are that your hands and feet become larger and features of your face may become more prominent. The cause is usually a small non-cancerous growth.
Patient information leaflet
تساقط الشعر الكربي
Telogen effluvium (hair loss) هو a condition where more than normal amounts of hair fall out. There is a general 'thinning' of the hair. Many other medications have been linked to telogen effluvium, but some من the most common are beta-blockers; retinoids, including excess vitamin A (often used for skin problems); anticoagulants (often called.
Patient information leaflet
نقص فيتامين أ
Vitamin ... Foods that contain vitamin A include liver, milk, eggs and fish-liver oils. Another substance called beta carotene (which is found in green leafy and orange/yellow الخضروات و fruits) can also be converted by your body to vitamin A. Mild forms of vitamin A deficiency can usually be treated without any long-term problems. Vitamin A.
Patient information leaflet
نمو محدود
Dwarfism is a medical or genetic condition which causes people to have restricted growth so that they are shorter than average. Specifically, people with dwarfism grow no higher than 4 ft 10 ins (147 cm). It can be due to literally hundreds of different causes, so the term actually includes many different medical conditions. The cause and type of.
قراءة إضافية ومراجع
- transforming growth factor beta induced; MedlinePlus, National Library of Medicine.
- Boutboul S, Black GC, Moore JE, Sinton J, Menasche M, Munier FL, Laroche L, Abitbol M, Schorderet DF. A subset of patients with epithelial basement membrane corneal dystrophy have mutations in TGFBI/BIGH3. Hum Mutat. 2006 Jun;27(6):553-7. doi: 10.1002/humu.20331.
- Clout NJ, Hohenester E. A model of FAS1 domain 4 of the corneal protein beta(ig)-h3 gives a clearer view on corneal dystrophies. Mol Vis. 2003 Sep 11;9:440-8.
- Kannabiran C, Klintworth GK. TGFBI gene mutations in corneal dystrophies. Hum Mutat. 2006 Jul;27(7):615-25. doi: 10.1002/humu.20334.
- Munier FL, Korvatska E, Djemai A, Le Paslier D, Zografos L, Pescia G, Schorderet DF. Kerato-epithelin mutations in four 5q31-linked corneal dystrophies. Nat Genet. 1997 Mar;15(3):247-51. doi: 10.1038/ng0397-247.
- Schmitt-Bernard CF, Chavanieu A, Derancourt J, Arnaud B, Demaille JG, Calas B, Argiles A. In vitro creation of amyloid fibrils from native and Arg124Cys mutated betaIGH3((110-131)) peptides, and its relevance for lattice corneal amyloid dystrophy type I. Biochem Biophys Res Commun. 2000 Jul 5;273(2):649-53. doi: 10.1006/bbrc.2000.2955.
- Yang J, Han X, Huang D, Yu L, Zhu Y, Tong Y, Zhu B, Li C, Weng M, Ma X. Analysis of TGFBI gene mutations in Chinese patients with corneal dystrophies and review of the literature. Mol Vis. 2010 Jun 30;16:1186-93.
تاريخ المقال
المقال متاح أيضًا باللغة الإنجليزية, الألمانية, إسبانية, الفرنسية, إيطالي, البرتغالية, الهندية, العبرية, العربية ,، و السويدية.
18 Aug 2020 | أحدث إصدار
1 Apr 2012 | نُشر في الأصل
انضم إلى المحادثة
شارك أفكارك أو تجاربك مع الآخرين في مجتمعات المرضى.
اسأل، شارك، تواصل.
تصفح المناقشات، اطرح الأسئلة، وشارك التجارب عبر مئات المواضيع الصحية.
اشترك في النشرة الإخبارية للمرضى
جرعتك الأسبوعية من النصائح الصحية الواضحة والموثوقة - مكتوبة لمساعدتك على الشعور بالاطلاع والثقة والتحكم.
من خلال الاشتراك، فإنك تقبل سياسة الخصوصية. يمكنك إلغاء الاشتراك في أي وقت. نحن لا نبيع بياناتك أبدًا.