Can I take Chaga and Turkey tail together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
- Add to preferred sources on Google
Taking chaga and turkey tail together may increase the risk of bleeding and could potentially lower your blood sugar levels more than expected. Both are medicinal mushrooms that have similar effects on the body.
Why this happens
Both chaga and turkey tail have 'antiplatelet' effects, meaning they make the blood less sticky and slower to clot. They also both possess hypoglycaemic properties, which means they can lower blood glucose levels. Taking them together creates an additive effect where these actions are strengthened.
What you should do
It is generally safe for most healthy people to take these together, but you should use caution. If you are scheduled for surgery, stop taking both at least two weeks beforehand. If you have diabetes or take blood-thinning medication (like warfarin or aspirin), you must speak to your doctor before combining these supplements. Monitor yourself for signs of easy bruising or unusual bleeding.
Important precautions
Kidney disease or history of kidney stones
Chaga is extremely high in oxalates, which can cause permanent kidney damage or acute kidney failure, especially in those with existing renal issues.
Diabetes
These mushrooms may significantly lower blood sugar levels, increasing the risk of hypoglycaemia (dangerously low blood sugar) if you are taking insulin or other diabetes medications.
Autoimmune diseases (e.g., Lupus, MS, Rheumatoid Arthritis)
These mushrooms can stimulate the immune system, which may worsen symptoms of autoimmune conditions or interfere with immunosuppressant medications.
Bleeding disorders or upcoming surgery
These mushrooms may slow blood clotting and increase the risk of bleeding; it should be avoided if you have a bleeding disorder or are scheduled for surgery.
Food and drink warnings
Alcohol
Chaga contains high levels of oxalates. Combining it with alcohol may increase the risk of kidney stones or kidney stress, as both substances can affect renal function. Use with caution.
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Drug interactions checker
Can I take Maitake and Turkey tail together?
There are no known harmful interactions between maitake and turkey tail mushrooms. Both are medicinal fungi that are often taken together to support the immune system. However, because both can stimulate the immune system, there is a theoretical possibility of an additive effect.

Drug interactions checker
Can I take Ashwagandha and Vitamin B12 together?
There are no known clinical interactions between ashwagandha and vitamin B12. It is generally considered safe to take these two supplements together.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
Article also available in English, German, Spanish, French, Italian, Portuguese, Hindi, Hebrew, Arabic, and Swedish.
25 Jan 2026 | Originally published
Join the conversation
Share your thoughts or experiences with others in our patient communities.

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.
More in drug interactions checker
- Can I take Alcohol and Rosuvastatin together?
- Can I take Amlodipine and Citalopram together?
- Can I take Apixaban and Metformin together?
- Can I take Apixaban and Sertraline together?
- Can I take Atorvastatin and Levothyroxine together?
- Can I take Atorvastatin and Paracetamol together?
- Can I take Clarithromycin and Sertraline together?
- Can I take Clopidogrel and Gabapentin together?
- Can I take Codeine and Morphine together?
- Can I take Evana heavy period relief and Mefenamic acid together?
- Can I take Fexofenadine and Sertraline together?
- Can I take Iron and Vitamin C together?
- Can I take Iron supplements and Pregabalin together?
- Can I take Lansoprazole and Rivaroxaban together?
- Can I take Losartan and Paracetamol together?
- Can I take Magnesium and Bisoprolol together?
- Can I take Mirtazapine and Sertraline together?
- Can I take Pregabalin and Sertraline together?
- Can I take Sertraline and Vitamin D3 together?
- Can I take Tetracycline and Calcium together?