Can I take Amlodipine and Danazol together?

لماذا يحدث هذا

Amlodipine is broken down in the liver by a specific enzyme (CYP3A4). Danazol interferes with this process by blocking the enzyme, which means the amlodipine stays in your system longer and reaches higher levels than normal.

You should speak to your doctor before taking these two medicines together. Your doctor may need to monitor your blood pressure more closely or adjust your dose of amlodipine while you are taking danazol. If you feel unusually dizzy or faint, contact your healthcare provider.

الحمل

You must not take danazol if you are pregnant or planning to become pregnant. It can cause the development of male physical characteristics in a female fetus. You must use effective, non-hormonal contraception (such as condoms) while taking it.

Grapefruit juice consumption

Avoid drinking large amounts of grapefruit juice. Grapefruit can increase the level of amlodipine in your blood, which may cause your blood pressure to drop too low.

Blood clots and stroke

Danazol significantly increases the risk of serious blood clots and can cause increased pressure inside the skull. Seek immediate medical help if you experience severe headaches, blurred vision, or sudden leg swelling.

عصير الجريب فروت

يمكن لعصير الجريب فروت أن يزيد من كمية الأملوديبين في دمك، مما قد يتسبب في انخفاض ضغط الدم بشكل كبير وزيادة خطر الآثار الجانبية مثل الصداع أو التورم. تجنب شرب كميات كبيرة من عصير الجريب فروت.

الكحول

While alcohol does not have a direct interaction, both alcohol and amlodipine can lower your blood pressure. Drinking alcohol while taking this medicine may make you feel dizzy, lightheaded, or faint.

Taking multiple medicines? Our مدقق تفاعلات الأدوية helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

إخلاء المسؤولية

هذه المعلومات لأغراض تعليمية عامة فقط ولا ينبغي الاعتماد عليها كبديل للنصيحة الطبية المهنية. استشر دائمًا طبيبك العام أو الصيدلي أو أي متخصص رعاية صحية مؤهل آخر قبل اتخاذ قرارات بشأن أدويتك. قد تختلف الظروف الفردية، ولا يمكن إلا لمتخصص الرعاية الصحية الذي يعرف تاريخك الطبي تقديم إرشادات مخصصة.