Can I take Solifenacin and St John's wort together?

لماذا يحدث هذا

St John's Wort is a 'liver enzyme inducer'. This means it speeds up the process by which your liver breaks down certain medicines. Because it makes your body process solifenacin much faster than usual, the levels of the medicine in your blood drop, preventing it from working properly.

You should avoid taking St John's Wort while you are prescribed solifenacin. If you are already taking both, do not stop the herbal remedy suddenly; instead, speak to your doctor or pharmacist. They can advise you on how to stop the supplement safely and may need to monitor your bladder symptoms or adjust your medication.

الجلوكوما

Do not take solifenacin if you have narrow-angle glaucoma, as it can increase the pressure in your eyes and worsen the condition.

احتباس البول

Do not take solifenacin if you have difficulty emptying your bladder (urinary retention), as it may make this problem worse.

الاكتئاب

If you are taking St John's wort for low mood, be aware that antidepressants can occasionally increase thoughts of self-harm or suicide, particularly when first starting treatment. Seek urgent medical help if your mood worsens.

تفاعلات الأدوية

St John's wort significantly reduces the effectiveness of many essential medicines, including the contraceptive pill, blood thinners (like warfarin), and transplant medications. Do not start it without a pharmacist checking all your other medicines.

متلازمة السيروتونين

Taking St John's wort with other antidepressants or triptans for migraine can cause serotonin syndrome, a potentially life-threatening reaction involving high body temperature, agitation, and muscle rigidity.

حساسية الضوء

يمكن لنبتة سانت جون أن تجعل بشرتك أكثر حساسية بشكل كبير لأشعة الشمس، مما يؤدي إلى حروق شمسية شديدة أو تفاعلات جلدية حتى مع التعرض المحدود.

الكحول

It is best to avoid or strictly limit alcohol while taking solifenacin. Both alcohol and solifenacin can cause drowsiness and blurred vision; combining them increases the risk of these side effects and may impair your coordination.

It is best to avoid or strictly limit alcohol while taking St John's Wort. Combining the two can increase drowsiness and dizziness, and may worsen the side effects of the herbal remedy.

عصير الجريب فروت

Grapefruit juice can increase the level of solifenacin in your blood, which may increase the risk of side effects such as dry mouth, constipation, and blurred vision. It is best to avoid drinking large amounts of grapefruit juice.

الكافيين (القهوة، الشاي، مشروبات الطاقة)

You should limit your intake of caffeine. Solifenacin is used to treat an overactive bladder, but caffeine is a natural diuretic and bladder irritant that can worsen symptoms like urgency and frequency, potentially making your medication less effective.

الأطعمة الغنية بالتيرامين (مثل الأجبان المعتقة، اللحوم المعالجة، صلصة الصويا، المارمايت، الفواكه الناضجة جدًا)

While less common than with older prescription antidepressants, St John's Wort can potentially interact with tyramine-rich foods, leading to a sudden, dangerous increase in blood pressure (hypertensive crisis). You should consume these foods in moderation.

Taking multiple medicines? Our مدقق تفاعلات الأدوية helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

إخلاء المسؤولية

هذه المعلومات لأغراض تعليمية عامة فقط ولا ينبغي الاعتماد عليها كبديل للنصيحة الطبية المهنية. استشر دائمًا طبيبك العام أو الصيدلي أو أي متخصص رعاية صحية مؤهل آخر قبل اتخاذ قرارات بشأن أدويتك. قد تختلف الظروف الفردية، ولا يمكن إلا لمتخصص الرعاية الصحية الذي يعرف تاريخك الطبي تقديم إرشادات مخصصة.