brain derived neurotrophic factor
آخر تحديث 13 مارس 2023
يتوافق مع الإرشادات التحريرية
- تنزيلتنزيل
- مشاركة
- Language
- نقاش
- نسخة صوتية
- أضف إلى المصادر المفضلة على جوجل
ال BDNF gene provides instructions for making a protein found in the brain and spinal cord called brain-derived neurotrophic factor. This protein promotes the survival of nerve cells (neurons) by playing a role in the growth, maturation (differentiation), and maintenance of these cells. In the brain, the BDNF protein is active at the connections between nerve cells (synapses), where cell-to-cell communication occurs. The synapses can change and adapt over time in response to experience, a characteristic called synaptic plasticity. The BDNF protein helps regulate synaptic plasticity, which is important for learning and memory.
Normal function
ال BDNF gene provides instructions for making a protein found in the brain and spinal cord called brain-derived neurotrophic factor. This protein promotes the survival of nerve cells (neurons) by playing a role in the growth, maturation (differentiation), and maintenance of these cells. In the brain, the BDNF protein is active at the connections between nerve cells (synapses), where cell-to-cell communication occurs. The synapses can change and adapt over time in response to experience, a characteristic called synaptic plasticity. The BDNF protein helps regulate synaptic plasticity, which is important for learning and memory.
The BDNF protein is found in regions of the brain that control eating, drinking, and body weight; the protein likely contributes to the management of these functions.
Conditions referring to this gene or chromosome
Other names
abrineurin
ANON2
BDNF_HUMAN
brain-derived neurotrophic factor
BULN2
neurotrophin
Related patient information and medicines
Patient information leaflet
مرض باركنسون
What is Parkinson's disease. باركنسون disease is a progressive neurological degeneration of certain cells (called dopaminergic cells) within a specific part of the brain (substantia nigra). The deficiency of dopamine leads to a movement disorder with Parkinson's disease symptoms. What causes Parkinso... PD is a disorder من the nervous system. A.
Patient information leaflet
أسباب فقدان الذاكرة والخرف
Alzheimer's disease This is the most common type of dementia, causing at least half of all cases, possibly up to three quarters. It is named after the doctor who first described it. In ألزهايمر disease the brain shrinks (atrophies) and the numbers of nerve fibres in the brain gradually reduce. The amount of some brain chemicals.
Patient information leaflet
مرض الزهايمر
مرض الزهايمر هو a cause of dementia. There is no cure and it can cause a great deal of distress for those affec... مرض الزهايمر هو the most common cause of dementia. الخرف is progressive and affects many brain functions, including memory. However it is known that there is a gradual process of damage to part of the brain called the.
Patient information leaflet
مرض هنتنغتون
مرض هنتنغتون is a genetically inherited condition that causes parts of the brain and nervous system to stop working properly over time. It is a slowly progressive condition that interferes with the movements of your body, thinking and judgement, and can lead to a change in your behaviour. The symptoms... What is Huntington's disease..
Patient information leaflet
تلعثم
A stammer (also called a stutter) هو common, especially in young children. For most young children, the stammer goes away without any treatment. What is a stammer. A stammer is a disorder of speech. There are stoppages and disruptions which interrupt the smooth flow and timing of the speech. There is no agreement on what exactly causes a stammer..
Patient information leaflet
نزيف تحت العنكبوتية
A subarachnoid haemorrhage (SAH) is a form of stroke in which bleeding occurs into the fluid-filled space surrounding the brain (called the subarachnoid space). It is usually caused by the rupture of a small berry-like swelling (called a berry aneurysm) on one of the arteries in the brain. SAH is a medical emergency. The risk of a further bleed is.
قراءة إضافية ومراجع
- brain derived neurotrophic factor; MedlinePlus, National Library of Medicine.
- Han JC, Liu QR, Jones M, Levinn RL, Menzie CM, Jefferson-George KS, Adler-Wailes DC, Sanford EL, Lacbawan FL, Uhl GR, Rennert OM, Yanovski JA. Brain-derived neurotrophic factor and obesity in the WAGR syndrome. N Engl J Med. 2008 Aug 28;359(9):918-27. doi: 10.1056/NEJMoa0801119.
- Rodriguez-Lopez R, Perez JM, Balsera AM, Rodriguez GG, Moreno TH, Garcia de Caceres M, Serrano MG, Freijo FC, Ruiz JR, Angueira FB, Perez PM, Estevez MN, Gomez EG. The modifier effect of the BDNF gene in the phenotype of the WAGRO syndrome. Gene. 2013 Mar 10;516(2):285-90. doi: 10.1016/j.gene.2012.11.073. Epub 2012 Dec 21.
- Sears C, Markie D, Olds R, Fitches A. Evidence of associations between bipolar disorder and the brain-derived neurotrophic factor (BDNF) gene. Bipolar Disord. 2011 Nov-Dec;13(7-8):630-7. doi: 10.1111/j.1399-5618.2011.00955.x.
- Shinawi M, Sahoo T, Maranda B, Skinner SA, Skinner C, Chinault C, Zascavage R, Peters SU, Patel A, Stevenson RE, Beaudet AL. 11p14.1 microdeletions associated with ADHD, autism, developmental delay, and obesity. Am J Med Genet A. 2011 Jun;155A(6):1272-80. doi: 10.1002/ajmg.a.33878. Epub 2011 May 12.
تاريخ المقال
المقال متاح أيضًا باللغة الإنجليزية, الألمانية, إسبانية, الفرنسية, إيطالي, البرتغالية, الهندية, العبرية, العربية ,، و السويدية.
13 مارس 2023 | أحدث إصدار
1 Mar 2013 | نُشر في الأصل
انضم إلى المحادثة
شارك أفكارك أو تجاربك مع الآخرين في مجتمعات المرضى.
اسأل، شارك، تواصل.
تصفح المناقشات، اطرح الأسئلة، وشارك التجارب عبر مئات المواضيع الصحية.
اشترك في النشرة الإخبارية للمرضى
جرعتك الأسبوعية من النصائح الصحية الواضحة والموثوقة - مكتوبة لمساعدتك على الشعور بالاطلاع والثقة والتحكم.
من خلال الاشتراك، فإنك تقبل سياسة الخصوصية. يمكنك إلغاء الاشتراك في أي وقت. نحن لا نبيع بياناتك أبدًا.