Orphenadrine
مراجعة من قبل Sid Dajaniآخر تحديث بواسطة Michael Stewart, MRPharmSLast updated 7 أغسطس 2023
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Orphenadrine is usually prescribed to relieve unwanted side-effects caused by certain other medicines.
When starting your treatment your doctor may give you a low dose and gradually increase it over a few days. This helps your body adjust to the medicine and reduces the risk of side-effects. Take it exactly as your doctor tells you to.
The most common side-effects are a dry mouth, blurred vision, and feeling sick (nausea).
At a glance
Orphenadrine is an antimuscarinic medicine.
It treats movement disorders caused by some other medicines, like antipsychotics.
It can also relieve muscle stiffness in Parkinson's disease.
Take orphenadrine exactly as your doctor tells you, three times a day.
Do not stop taking orphenadrine suddenly without speaking to your doctor.
Common side-effects include dry mouth, sickness, blurred vision, and dizziness.
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تابع القراءة أدناه
About orphenadrine
نوع الدواء | An antimuscarinic medicine |
يستخدم لـ | Unwanted 'extrapyramidal side-effects' caused by some medicines |
متوفر كـ | الأقراص والأدوية السائلة الفموية |
Orphenadrine is an antimuscarinic medicine. It is prescribed for people who have unwanted movement disorders as a side-effect of taking certain other medicines, such as some antipsychotic medicines. These movement disorders are often referred to as 'extrapyramidal side-effects' and include things like uncontrolled face and body movements, tremor, and restlessness.
Orphenadrine can also be given to relieve muscle stiffness in people with مرض باركنسون, although other medicines are generally preferred.
Before taking orphenadrine
العودة إلى المحتوياتSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking orphenadrine it is important that your doctor knows:
إذا كنت حاملاً أو مرضعة.
إذا كان لديك أي مشاكل في طريقة عمل الكبد لديك، أو طريقة عمل الكلى لديك.
If you have any problems with your heart or blood vessels.
If you have prostate problems, or if you have been experiencing difficulty passing urine.
If you have been constipated for more than a week.
If you have a condition which causes raised pressure in your eyes, such as glaucoma.
إذا كنت تعاني من ارتفاع ضغط الدم.
إذا كنت تعاني من حالة تسبب ضعف العضلات، تُسمى الوهن العضلي الوبيل.
If you have ever had a mental health problem called psychosis.
إذا كنت تعاني من اضطراب دم وراثي نادر يسمى البورفيريا.
إذا كنت تتناول أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.
إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.
تابع القراءة أدناه
How to take orphenadrine
العودة إلى المحتوياتBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about orphenadrine and will provide you with a full list of the side-effects which you may experience from taking it.
Take orphenadrine exactly as your doctor tells you to. When starting this treatment your doctor may give you a low dose and gradually increase it every 2-3 days until your symptoms improve. Carefully follow the directions your doctor gives to you. Once you are on a full dose, it is likely that you will be taking three doses of orphenadrine a day, although it may be more or less often than this.
You can take orphenadrine before or after your meals. Try to take your doses at the same times of day each day, as this will help you to remember to take your doses regularly.
If you forget to take a dose, take it as soon as you remember unless your next dose is due. If it is nearly time for your next dose then take the next dose when it is due but leave out the forgotten dose. Do not take two doses together to make up for a missed dose.
تحقيق أقصى استفادة من علاجك
العودة إلى المحتوياتحاول الحفاظ على مواعيدك المنتظمة مع طبيبك. هذا لكي يتمكن طبيبك من متابعة تقدمك.
If you buy any medicines, check with a pharmacist that they are safe to take with orphenadrine. Some antihistamines and some strong painkillers can interfere with orphenadrine and increase the risk of side-effects.
If you are having an operation or any dental treatment, tell the person carrying out the treatment that you are taking orphenadrine.
If you have been taking orphenadrine for some time, do not stop taking it without speaking with your doctor first. Stopping suddenly can cause problems so your doctor will want to reduce your dose gradually if this becomes necessary.
Ask your doctor for advice before drinking alcohol while you are on orphenadrine. Your doctor may recommend that you do not drink alcohol because it increases the possibility of side-effects such as feeling sleepy.
تابع القراءة أدناه
Can orphenadrine cause problems?
العودة إلى المحتوياتAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with orphenadrine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common orphenadrine side-effects (these affect fewer than 1 in 10 people) | ماذا يمكنني أن أفعل إذا واجهت هذا؟ |
جفاف الفم | Try chewing sugar-free gum or sucking sugar-free sweets. If this becomes troublesome, speak with your doctor |
الشعور بالغثيان (الغثيان) أو التقيؤ (القيء) | التزم بالأطعمة البسيطة - تجنب الوجبات الغنية أو الحارة |
Blurred vision, feeling dizzy or restless | إذا حدث هذا، لا تقم بالقيادة ولا تستخدم الأدوات أو الآلات |
إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الدواء، تحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.
How to store orphenadrine
العودة إلى المحتوياتاحفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.
احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.
معلومات هامة عن جميع الأدوية
العودة إلى المحتوياتمعلومات هامة عن جميع الأدوية
لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، اذهب إلى قسم الحوادث والطوارئ في مستشفى منطقتك. خذ العبوة معك، حتى لو كانت فارغة.
هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.
لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.
إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.
الإبلاغ عن الآثار الجانبية لدواء أو لقاح
إذا واجهت آثارًا جانبية، يمكنك الإبلاغ عنها عبر الإنترنت من خلال Yellow Card website.

غير متأكد من خلط الأدوية؟
تحقق من التفاعلات المحتملة بين الأدوية والمكملات الغذائية والأطعمة قبل تناولها معًا.
الأسئلة الشائعة
What kind of symptoms are 'extrapyramidal side-effects' that orphenadrine helps with?
Extrapyramidal side-effects are movement disorders that can be caused by certain medicines, like some antipsychotics. They include things like involuntary movements of the face and body, shaking (tremor), and feeling restless.
Can orphenadrine be used for Parkinson's disease?
Yes, orphenadrine can be used to help relieve muscle stiffness in people with Parkinson's disease. However, the article notes that other medicines are generally preferred for this condition.
Are there certain medical conditions that might prevent me from taking orphenadrine?
Yes, there are several conditions your doctor needs to be aware of before you start taking orphenadrine. These include problems with your liver or kidneys, heart or blood vessel issues, prostate problems, difficulty passing urine, long-term constipation, certain types of glaucoma, high blood pressure, myasthenia gravis (muscle weakness), a history of psychosis, or a rare blood disorder called porphyria. Your doctor will assess if the medicine is suitable for you.
I'm on other medications. Do I need to tell my doctor before starting orphenadrine?
Yes, it is very important to tell your doctor about all other medicines you are taking. This includes any you've bought without a prescription, as well as herbal and complementary medicines, as some can interfere with orphenadrine.
How should I store orphenadrine at home?
You should keep all orphenadrine medicine out of reach and sight of children. Store it in a cool, dry place, away from direct heat and light.
What should I do if I accidentally take too much orphenadrine?
If you suspect that you or someone else might have taken an overdose of orphenadrine, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty.
Can I share my orphenadrine with someone else if they have similar symptoms?
No, you should never give your orphenadrine to other people, even if their condition seems to be the same as yours. This medicine is prescribed specifically for you.
قراءة إضافية ومراجع
- Manufacturer's PIL, Orphenadrine Hydrochloride 50 mg/5 ml Oral Solution; Rosemont Pharmaceuticals Limited, The electronic Medicines Compendium. Dated July 2020.
- الأدوية كاملة BNF الطبعة 89; الجمعية الطبية البريطانية والجمعية الملكية الصيدلانية لبريطانيا العظمى، لندن.
تابع القراءة أدناه
About the authorView full bio

مايكل ستيوارت، MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

سيد داجاني
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
تاريخ المقال
تمت كتابة المعلومات على هذه الصفحة ومراجعتها من قبل أطباء مؤهلين.
المراجعة التالية مستحقة: 6 أغسطس 2026
7 أغسطس 2023 | أحدث إصدار

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