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Apply tretinoin exactly as your doctor tells you to. You will be asked to apply it either once or twice a day.

Your skin may become more sensitive to sunlight than usual. Avoid strong sunlight and do not use sunbeds.

You should avoid getting pregnant. Ask your doctor about suitable contraception.

نظرة سريعة

  • Tretinoin is a topical retinoid medicine used to treat mild-to-moderate acne.

  • It works by unblocking pores and helping to reduce inflammation.

  • Do not use tretinoin if you are pregnant or trying to conceive.

  • Apply a thin layer to affected areas, usually once or twice daily, as directed by your doctor.

  • Your skin may become more sensitive to sunlight, so use sun protection.

  • It can take several weeks to see an improvement, and side-effects like skin irritation may occur.

About tretinoin

نوع الدواء

A rub-on (topical) retinoid

يستخدم لـ

Mild-to-moderate acne

يُعرف أيضًا باسم

Aknemycin® Plus (contains tretinoin with erythromycin); Treclin® (contains tretinoin with clindamycin)

متوفر كـ

Solution and gel

Acne is the common cause of spots. Most people with acne are aged between 12 and 25, but some older and younger people are affected too. Small sebaceous glands lie just under your skin surface and make an oil (sebum) that keeps your skin supple and smooth. Tiny pores on your skin allow the sebum to come on to the surface of your skin. In acne, some of these pores become blocked, causing small pimples, blackheads and whiteheads (comedones).

Applying tretinoin to the areas of your skin with acne will help to unblock pores and treat blackheads or whiteheads. It also has an effect on reducing inflammation. Two brands of rub-on tretinoin are currently available. Aknemycin® Plus solution also contains an antibacterial agent called erythromycin. Treclin® gel contains an antibacterial agent called clindamycin.

Before using tretinoin

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start using tretinoin it is important that your doctor knows:

  • If you are pregnant, trying for a baby or breastfeeding. You must not use tretinoin if you could be pregnant.

  • If you have a skin problem other than acne, such as if you have eczema or rosacea.

  • If you or any close family members have ever had skin cancer.

  • If you are taking or using any other medicines. This includes any creams you are using which are available to buy without a prescription.

  • إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.

How to use tretinoin

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about tretinoin and will provide you with a full list of the side-effects which you may experience from using it.

  • Apply tretinoin exactly as your doctor tells you to. It is best if you wash and gently dry the affected areas of your skin before you apply it. A general point is that you should apply it to all of the area where your spots occur and not just to each spot. It is usual to apply the solution (Aknemycin® Plus) once or twice a day. Treclin® gel is applied once daily at bedtime. You only need to apply a thin layer. Remember to wash your hands after you have finished applying the solution/gel.

  • If you have recently been using a preparation for your acne that causes your skin to peel, allow your skin to recover for a few days before you start using tretinoin.

  • Do not use tretinoin on any areas of your skin which are sunburnt or sore. Also, try to avoid getting it on the sensitive areas of your skin in or around your nostrils, your eyes and your mouth. Try not to let it build up in the folds or creases of your skin.

تحقيق أقصى استفادة من علاجك

  • It is recommended that you use a mild soap and lukewarm water to wash with, as very hot or cold water can worsen acne. You cannot clean off blackheads. The black tip of a blackhead is actually a skin pigment and cannot be removed by cleaning or scrubbing.

  • If your skin becomes very dry, it may help to use a moisturising cream (preferably a fragrance-free and water-based cream). Do not use ointments or oil-rich creams, as these could clog your pores again.

  • You can use make-up and moisturisers, but do not apply them at the same time as you use tretinoin. Try to avoid any skin products which exfoliate or dry your skin.

  • Tretinoin can make your skin more sensitive to sunlight than usual. A sun protection cream can help if you are out in the sun on bright days, even if it is cloudy. Do not use sunbeds.

  • It is normal for tretinoin treatment to take several weeks before there is a noticeable improvement in your skin. The most common reason for treatment failure is stopping treatment too soon thinking it is not working. If there is no improvement despite having used it for eight weeks, speak with your doctor again as there are other treatments which could be more suited to your condition.

  • You should avoid getting pregnant while you are using tretinoin as there is a slight risk of harm to unborn babies. If necessary, discuss with your doctor which types of contraception are suitable for you and your partner.

  • Once your spots have cleared, acne commonly flares up again if you stop treatment. To prevent this, it is usual to carry on with a maintenance treatment after your spots have gone. Your doctor will recommend a suitable preparation for you to use. It is common to need maintenance treatment for a number of years to keep acne away.

Can tretinoin solution or gel cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with rub-on tretinoin preparations. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Tretinoin solution/gel side-effects

ماذا يمكنني أن أفعل إذا واجهت هذا؟

Skin irritation, redness, burning, dry or peeling skin

Reduce how often you apply tretinoin for a few days to see if this settles. If it is severe or troublesome, speak with your doctor

مهم: Aknemycin® Plus is an alcohol-based product and is flammable. Do not light a cigarette or use a naked flame until the solution has completely dried on your skin.

If you experience any other symptoms which you think may be due to tretinoin, speak with your doctor or pharmacist for further advice.

How to store tretinoin

  • احفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.

  • احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.

معلومات هامة عن جميع الأدوية

معلومات هامة عن جميع الأدوية

If you buy any medicines, always check with a pharmacist that they are safe to use with your other medicines.

This preparation is for external use only. If you suspect that someone has swallowed some of it by accident, contact the accident and emergency department of your local hospital for advice.

إذا كنت ستخضع لعملية جراحية أو علاج أسنان، أخبر الشخص الذي يقوم بالعلاج عن الأدوية التي تستخدمها.

هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.

لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.

إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.

الإبلاغ عن الآثار الجانبية لدواء أو لقاح

إذا واجهت آثارًا جانبية، يمكنك الإبلاغ عنها عبر الإنترنت من خلال موقع بطاقة صفراء.

مدقق الأعراض

غير متأكد من خلط الأدوية؟

تحقق من التفاعلات المحتملة بين الأدوية والمكملات الغذائية والأطعمة قبل تناولها معًا.

الأسئلة الشائعة

Does tretinoin help with closed comedones?

Yes, tretinoin helps to unblock pores, which treats blackheads and whiteheads (comedones).

Does treclin contain tretinoin?

Yes, Treclin® gel is one brand of rub-on tretinoin that is available. It also contains clindamycin, an antibacterial agent.

How long does it typically take to see an improvement in acne after starting tretinoin?

It is normal for tretinoin treatment to take several weeks before you notice an improvement in your skin. The most common reason for treatment failure is stopping too soon because you think it isn't working. If there's no improvement after eight weeks, you should speak with your doctor again.

Can I use other skincare products like make-up or moisturisers while using tretinoin?

Yes, you can use make-up and moisturisers, but you should not apply them at the same time as tretinoin. You should also try to avoid any skin products that exfoliate or dry your skin.

What should I do if my skin becomes very dry from using tretinoin?

If your skin becomes very dry, using a moisturising cream can help. It's best to choose a fragrance-free and water-based cream. Avoid using ointments or oil-rich creams, as these could clog your pores again.

قراءة إضافية ومراجع

عن المؤلفعرض السيرة الذاتية الكاملة

صورة المؤلف

مايكل ستيوارت، MRPharmS

مدير مراجعة النشرات الطبية – متعاقد، صيدلي

بكالوريوس الصيدلة (مع مرتبة الشرف)، عضو الجمعية الملكية للصيادلة

مايكل هو صيدلي مجتمعي يمارس عمله في منطقة ميدلاندز وجنوب يوركشاير ولديه أكثر من 20 عامًا من الخبرة في تقديم المشورة بشأن الأدوية والحالات الطبية. لديه خلفية قوية في تدريب الرعاية الصحية، حيث قام بإنتاج وتقديم دورات تدريبية لفرق الصيدلة وموظفي دور الرعاية السكنية، بما في ذلك الممرضات. كما ساهم في مجالس استشارية للصيدلة لإدارة الحالات ذات الحدة المنخفضة في المجتمع.

حول المراجع

صورة المؤلف

سيد داجاني

تخرج سلطان دجاني من كلية الصيدلة في لندن عام 1994 وأصبح أصغر عضو منتخب في مجلس الجمعية الملكية للصيدلة منذ تأسيسها في عام 1842.

تاريخ المقال

تمت كتابة المعلومات على هذه الصفحة ومراجعتها من قبل أطباء مؤهلين.

  • المراجعة التالية مستحقة: 22 مايو 2027
  • 9 يونيو 2024 | أحدث إصدار

    آخر تحديث بواسطة

    مايكل ستيوارت، MRPharmS

    مراجعة من قبل

    سيد داجاني
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