Clobetasol propionate for severe inflammatory skin conditions
Clarelux, ClobaDerm, Dermovate, Etrivex
مراجعة من قبل Sid Dajaniآخر تحديث بواسطة Michael Stewart, MRPharmSLast updated 25 Apr 2024
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You only need to use a small amount of this preparation. Apply a small amount just to the areas affected, and then massage it gently into the skin.
Topical corticosteroids should not be used for long periods of time or on large areas of the body, especially in children. This is due to the risk of serious side-effects with long-term use.
As a guide, clobetasol should not be used continuously for more than 5 days in children and 7 days in adults, unless your doctor gives specific instructions to do so.
Clobetasol propionate (unless combined with an antibacterial agent) should not be used on any infected areas of skin.
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تابع القراءة أدناه
About clobetasol propionate
نوع الدواء | A very potent topical corticosteroid |
يستخدم لـ | حالات الجلد الالتهابية مثل الإكزيما الشديدة والتهاب الجلد |
يُعرف أيضًا باسم | Clarelux®; ClobaDerm®; Dermovate®; Etrivex® |
متوفر كـ | Cream, ointment, foam, scalp application and shampoo |
Clobetasol propionate is classed as a very potent topical corticosteroid. Topical corticosteroids are also referred to as الستيرويدات الموضعية. Topical steroids are used in addition to moisturisers (emollients) for treating inflammatory skin conditions such as الأكزيما و التهاب الجلد. A topical steroid is used when patches of eczema or dermatitis flare up. Clobetasol propionate relieves the symptoms of a flare-up by reducing inflammation, itching and redness. It is not a cure for the condition, but it will help to relieve the symptoms.
Specialist skin doctors may on occasion prescribe a short course of clobetasol propionate for the treatment of psoriasis, although it is not generally recommended for this skin condition. Clobetasol propionate is not recommended for use in children, although again, it may be prescribed for a child by a specialist doctor under certain circumstances.
Clobetasol propionate is available as a number of different preparations. It is likely you will be prescribed a cream if the affected areas of your skin are moist or weeping, or an ointment if your skin is dry. It is also available as a shampoo and as an application for the scalp.
There is also a preparation available which contains two antibacterial agents called neomycin and nystatin. You may be prescribed this preparation for short-term use if your skin has become infected. It is typically used twice a day for one week only.
Before using clobetasol propionate
العودة إلى المحتوياتTo make sure this is the right treatment for you, before you start using clobetasol propionate it is important that your doctor knows:
إذا كان لديك أي مناطق من الجلد المصاب.
إذا كنت تعاني من الوردية أو حب الشباب.
إذا كنت حاملاً أو مرضعة.
إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه مستحضر جلدي.
تابع القراءة أدناه
How to use clobetasol propionate
العودة إلى المحتوياتBefore you start using the preparation, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about topical steroids and will give you full instructions for using the preparation you have been given. It will also provide you with a list of the side-effects that you may experience.
Apply a small amount of cream/ointment to the areas of skin which are inflamed. Then gently rub it into the skin until it has disappeared. Do not use clobetasol propionate on any open sores or areas of infected skin unless you have a preparation which contains antibacterial agents (clobetasone with neomycin and nystatin). If you are using this preparation, use it regularly twice daily for one week only, unless you have been directed otherwise by your doctor.
The amount of topical steroid cream/ointment that you should apply is commonly measured by fingertip units (FTUs). One FTU is the amount of cream or ointment that is squeezed out along an adult's fingertip (that is, from the very end of the finger to the first crease in the finger). As a guide, one FTU is enough to cover an area twice the size of an adult hand. Your doctor will give you an idea of how many FTUs you will need to cover the area of your skin which is affected.
If you are using a scalp application, apply a few drops of liquid or a small amount of foam to the affected areas of your scalp, rub it in gently, and then allow the areas to dry again naturally. If you are using Etrivex® shampoo, apply a small amount to the affected areas of your hair when it is dry, massage it in gently, and then rinse it off after 15 minutes. As a guide to how much to use, half a tablespoon of shampoo (7.5 ml) is sufficient to cover the whole of your scalp.
If you are using Clarelux® cutaneous foam, hold the container upside-down so the nozzle is pointing downwards. Press the button to deliver a teaspoon-sized amount of foam directly onto the affected skin and gently massage the area until the foam disappears. Try not to spray the foam into your hands first as it will quickly start to melt. Avoid contact with the eyes, nose and mouth.
Your doctor will tell you how often to apply clobetasol propionate. It must not be applied more than twice a day, and once a day is often sufficient.
إذا كنت تستخدم أكثر من نوع واحد من الكورتيكوستيرويدات الموضعية، تأكد من أنك تعرف متى وأين تستخدم كل منها. إذا كنت غير متأكد، تحقق مع طبيبك أو اسأل الصيدلي للحصول على مزيد من النصائح.
After you have applied clobetasol propionate, remember to wash your hands (unless your hands are the treated area).
If you are using clobetasol propionate for psoriasis, make sure you follow your doctor's instructions carefully. It should not be used for large areas of psoriasis or for long periods of time, as these can cause your symptoms to flare up again afterwards.
Clobetasol propionate is not suitable for use in children unless it is has been advised by a skin specialist. This is because children are particularly susceptible to side-effects from strong topical steroids. The main concern is for children who need frequent courses, as it can have an effect on their growth and this will need to be monitored. If your child has been prescribed clobetasol propionate, follow the directions you have been given very carefully, and do not use it for longer than you have been told to. As a general rule, it should not be used for more than five days in children.
تحقيق أقصى استفادة من علاجك
العودة إلى المحتوياتIf you are using a moisturiser along with this preparation, apply the moisturiser first. Then wait 10-15 minutes before applying clobetasol propionate. This allows time for the moisturiser to be absorbed before the topical corticosteroid is applied. Your skin should be moist but not slippery when you apply clobetasol propionate.
Do not use clobetasol propionate on your face.
ما لم ينصحك طبيبك بذلك، لا تقم بوضع ضمادة أو غطاء على المنطقة التي يتم علاجها، حيث سيؤدي ذلك إلى زيادة امتصاص المستحضر وزيادة خطر الآثار الجانبية.
Continue to use clobetasol propionate until the flare-up is controlled, and then stop it. A course of treatment for 7-14 days is usually sufficient. If your symptoms have not improved after this time (or if they get worse), speak again with your doctor for further advice.
After you finish using clobetasol propionate, continue to use your moisturiser every day. This will help to prevent a further flare-up. Your doctor may also prescribe a less potent steroid cream for you to use when needed.
تابع القراءة أدناه
Can clobetasol propionate cause problems?
العودة إلى المحتوياتAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. You can reduce the risk of side-effects from topical corticosteroids like clobetasol propionate, by applying the preparation thinly, no more than twice a day, and to the affected areas only.
Side-effects of clobetasol propionate | ماذا يمكنني أن أفعل إذا واجهت هذا؟ |
A burning sensation or smarting | قد تحدث هذه الأمور في الأيام القليلة الأولى ولكنها عادة ما تتحسن بعد ذلك |
Thinning of the skin, permanent stretchmarks, allergic contact dermatitis, acne, rosacea, and hair growth at the site of application | These would normally only affect you if you use clobetasol propionate for long periods of time |
Clobetasol propionate may get through your skin and into your bloodstream | This usually causes no problem unless you use clobetasol propionate regularly on large areas of your skin |
If you experience any other symptoms which you think may be due to clobetasol propionate, speak with your doctor or pharmacist for further advice.
How to store clobetasol propionate
العودة إلى المحتوياتاحفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.
احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.
معلومات هامة عن جميع الأدوية
العودة إلى المحتوياتمعلومات هامة عن جميع الأدوية
تأكد من أن الشخص الذي يصف لك هذا الدواء على علم بأي أدوية أخرى تتناولها أو تستخدمها. يشمل ذلك الأدوية التي تشتريها والأدوية العشبية والطب البديل.
قبل استخدام هذا الدواء، أخبر طبيبك إذا كنت قد تعرضت لأي رد فعل تحسسي بعد تناول أو استخدام أي دواء.
لا تستخدم أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أن شخصًا ما قد ابتلع بعض الدواء عن طريق الخطأ، فاتصل بقسم الحوادث والطوارئ في مستشفى منطقتك للحصول على المشورة.
إذا كنت ستخضع لعملية جراحية أو علاج أسنان، أخبر الشخص الذي يقوم بالعلاج بالأدوية التي تتناولها أو تستخدمها.
إذا اشتريت أي أدوية، تحقق مع الصيدلي من أنها آمنة لتناولها مع الأدوية الأخرى التي تتناولها.
هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.
لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.
إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.
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قراءة إضافية ومراجع
- Manufacturer's PIL, Dermovate® Cream; GlaxoSmithKline UK, The electronic Medicines Compendium. Dated August 2023.
- Manufacturer's PIL, Dermovate® Scalp Application; GlaxoSmithKline UK, The electronic Medicines Compendium. Dated August 2023.
- الأدوية كاملة BNF الطبعة 89; الجمعية الطبية البريطانية والجمعية الملكية الصيدلانية لبريطانيا العظمى، لندن.
تابع القراءة أدناه
About the author

مايكل ستيوارت، MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
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25 Apr 2024 | أحدث إصدار

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