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Nonsyndromic dilated cardiomyopathy

آخر تحديث 4 ديسمبر 2025

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Dilated cardiomyopathy is a form of heart disease in which the heart (cardiac) muscle becomes thin and enlarged (dilated). The dilation, which typically starts in the lower left chamber of the heart (left ventricle), makes it harder for the heart to pump blood to the rest of the body. 

الوصف

Dilated cardiomyopathy is a form of heart disease in which the heart (cardiac) muscle becomes thin and enlarged (dilated). The dilation, which typically starts in the lower left chamber of the heart (left ventricle), makes it harder for the heart to pump blood to the rest of the body. 

Dilated cardiomyopathy is called nonsyndromic dilated cardiomyopathy when it cannot be explained by other causes, such as a heart attack or damage to the valves of the heart, and is not associated with signs and symptoms that affect other parts of the body.  

The signs and symptoms of nonsyndromic dilated cardiomyopathy vary among affected individuals, even among members of the same family. The signs and symptoms typically begin in mid-adulthood, but they can occur at any time from infancy to late adulthood. Affected individuals may have a sensation of fluttering or pounding in the chest (palpitations); shortness of breath, especially when lying down or during physical activity; fatigue; and swelling of the legs and feet. Affected individuals may also have episodes of dizziness or fainting (syncope). 

Over time, people with nonsyndromic dilated cardiomyopathy may develop life-threatening complications, which can include abnormal heart rhythms (arrhythmias) and heart failure. Although uncommon, sudden death can occur in people with nonsyndromic dilated cardiomyopathy, even if they have no other symptoms of the condition.

Inheritance patterns

The source lists the following possible inheritance patterns: Autosomal dominant+New variant; X-linked; Autosomal recessive. More than one pattern can apply in different cases.

Related genes

Other names

DCM

Familial dilated cardiomyopathy

Idiopathic dilated cardiomyopathy

Related clinical trials

Related patient information and medicines

اعتلال عضلة القلب التوسعي

Patient information leaflet

اعتلال عضلة القلب التوسعي

Dilated cardiomyopathy is a condition where the heart muscle becomes stretched and thin. The heart becomes enlarged (dilates) and pumps blood less well. These change... Dilated cardiomyopathy is uncommon, but it is the most common type of cardiomyopathy. One estimate is that between 1 in every 2,500, to 1 in every 1,250 people have it; however,.

أمراض القلب

Patient information leaflet

أمراض القلب

Valvular... Heart rhythm problems See the separate leaflet called Abnormal Heart Rhythms (Arrhythmias). Cardiomyopathy Cardiomyopathies are diseases that affect the heart muscle. There are several types: Hypertrophic cardiomyopathy. Dilated cardiomyopathy. Restrictive cardiomyopathy: this is a rare form of cardiomyopathy in which the heart muscle.

الرجفان الأذيني

Patient information leaflet

الرجفان الأذيني

الرجفان الأذيني (AF) هو an abnormal fast irregular heartbeat. An abnormal heartbeat rhythm is called an arrhythmia. For example, AF occurs in some people with heart valve problems , pericardial disease , اعتلال عضلة القلب التوسعي و hypertrophic cardiomyopathy. Other conditions and situations that may trigg... See the separate leaflet called.

داء ترسب الأصبغة الدموية

Patient information leaflet

داء ترسب الأصبغة الدموية

As haemochromatosis progresses, more specific symptoms develop due to organ damage but these are significantly less common nowadays due to earlier diagnosis. Disease of the heart muscle (cardiomyopathy). The possible complications of haemochromatosis include: Diabetes due to damage to the pan... قلب disease -for example it can lead to the heart.

اضطرابات نظم القلب

Patient information leaflet

اضطرابات نظم القلب

An arrhythmia هو an abnormal rate and/or rhythm of the heartbeat due to some problem with the electrical conducting system of the heart. What is an arrhythmia. An ... Ageing (age-related degeneration) around the conducting fibres may cause complete heart block. A disorder of the heart muscle (cardiomyopathy). See the separate leaflets called.

أمراض صمامات القلب

Patient information leaflet

أمراض صمامات القلب

If rheumatic fever is the cause then symptoms often start between the ages of 20 and 50 years, about 10-20 years after having had an episod... Other causes of heart valve disease Other causes of heart valve disease include: Deposits of calcium (calcification) in parts of the valve. This is the most common cause of aortic stenosis in older people..

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  • 4 ديسمبر 2025 | أحدث إصدار
  • 1 Nov 2025 | نُشر في الأصل

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