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كلورديازيبوكسيد - بنزوديازيبين

Librium

Chlordiazepoxide is likely to affect your reactions and ability to drive. These effects can last into the following day. It is an offence to drive while your reactions are impaired.

Do not drink alcohol while you are on chlordiazepoxide.

Your course of treatment will be as short as possible. This can range from one or two days, to up to a maximum of four weeks of treatment.

نظرة سريعة

  • Chlordiazepoxide is a medicine used to treat anxiety and symptoms of alcohol withdrawal.

  • It works by affecting brain chemicals to create a calming and muscle-relaxing effect.

  • You should take chlordiazepoxide exactly as your doctor tells you.

  • It is usually prescribed for short periods to reduce the risk of dependence.

  • تشمل الآثار الجانبية الشائعة الشعور بالنعاس أو الضعف أو الدوار.

  • Do not drive or drink alcohol while taking chlordiazepoxide.

  • Tell your doctor if you are pregnant, breastfeeding, or have certain health conditions.

About chlordiazepoxide

نوع الدواء

A benzodiazepine

يستخدم لـ

Anxiety; alcohol withdrawal

يُعرف أيضًا باسم

Librium®

متوفر كـ

كبسولات

Chlordiazepoxide works by affecting the way certain substances in your brain (called neurotransmitters) pass messages to your brain cells. It has a calming effect on various functions of your brain. The calming effect is helpful in people with anxiety, so chlordiazepoxide is sometimes prescribed to ease anxiety. If you have been prescribed it for this reason, you will be prescribed it for a very short period of time.

Chlordiazepoxide also has a muscle-relaxing effect. It is used to help relieve the symptoms of alcohol withdrawal. When you are alcohol-dependent, your body becomes used to lots of alcohol. This means that your body starts to develop withdrawal symptoms 3-8 hours after your last drink, as the effect of the alcohol wears off. So, even if you want to stop drinking, it is often difficult because of the withdrawal symptoms. Detoxification, or 'detox', involves taking a short course of a medicine which helps to prevent withdrawal symptoms when you stop drinking alcohol. The most commonly used medicine for this is chlordiazepoxide.

Before taking chlordiazepoxide

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking chlordiazepoxide it is important that your doctor knows:

  • إذا كنت حاملاً أو مرضعة.

  • If you have any breathing problems - for example, if you have a problem where you stop breathing for short periods at night (a condition called sleep apnoea).

  • إذا كان لديك أي مشاكل في طريقة عمل الكبد لديك، أو إذا كان لديك أي مشاكل في طريقة عمل الكلى لديك.

  • If you have a mental health problem. This includes conditions such as psychosis, depression, obsessive conditions, phobias and personality disorders.

  • If you have ever had a drug or alcohol addiction and you are not being prescribed chlordiazepoxide for this reason.

  • If you have a condition causing muscle weakness, such as myasthenia gravis.

  • If you have any problems that affect your balance or co-ordination, or affect your ability to walk.

  • إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.

  • إذا كنت تتناول أي أدوية أخرى. يشمل ذلك أي أدوية يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.

How to take chlordiazepoxide

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about chlordiazepoxide, and it will also provide you with a full list of the side-effects which you could experience from taking it.

  • Your doctor will tell you what dose of chlordiazepoxide to take, and how often to take it. The directions will also be printed on the label of the pack to remind you about what was said to you. Take your doses exactly as your doctor tells you to. As a guide:

    • If you are taking chlordiazepoxide for anxiety, you will probably be prescribed one capsule to take three times a day.

    • If you are taking it to prevent alcohol withdrawal symptoms, it is usual to take four doses a day. You will be prescribed a high dose on the first day you stop drinking, then your dose will gradually reduce over the next 5-10 days.

  • You can take chlordiazepoxide either with or without food.

  • If you forget to take a dose, take it when you remember. If when you remember, it is almost time to take your next dose, leave out the missed dose and take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.

تحقيق أقصى استفادة من علاجك

  • Remember to keep any regular appointments with your doctor or clinic. This is so your doctor can check on your progress.

  • Chlordiazepoxide is likely to affect your reactions and ability to drive. It is an offence to drive while your reactions are impaired. Do not drive until you know how you react, especially when you first start treatment. Please also be aware that the effects of chlordiazepoxide can last into the following day. Even if your driving ability is not impaired, should you drive, you are advised to carry with you some evidence that the medicine has been prescribed for you - a repeat prescription form or a patient information leaflet from the pack is generally considered suitable.

  • Chlordiazepoxide is taken for short periods of time only, often for just a few days. This is because taking it for longer can lead to you feeling dependent on it. Also, your body gets used to it quickly, and after this time it is unlikely to have the same effect.

  • If you are going through detox, you will have agreed not to drink any alcohol. Even if you are not taking chlordiazepoxide for this reason, you should still not drink alcohol. It will increase the risk of you experiencing unwanted effects.

  • Your doctor could recommend that you reduce your dose of chlordiazepoxide gradually when it is time to stop taking it. This is to reduce the risk of you experiencing withdrawal effects. Follow carefully any instructions your doctor gives to you.

  • Chlordiazepoxide can harm an unborn child so you must avoid getting pregnant or fathering a child while you are taking it. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. You must use effective contraception during treatment and for seven months afterwards for women or four months afterwards for men. If you want to have a family, discuss this with your doctor so that you can be given advice from a specialist.

  • If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment that you are taking chlordiazepoxide. This is because chlordiazepoxide increases the effects of some anaesthetics.

  • After detox, it is thought that you are less likely to go back to drinking heavily if you have counselling to help you to stay off alcohol. Your doctor, practice nurse, or local drug and alcohol unit can provide ongoing support when you are trying to stay off alcohol. Self-help groups such as Alcoholics Anonymous have also helped many people.

Can chlordiazepoxide cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with chlordiazepoxide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common chlordiazepoxide side-effects

ماذا يمكنني أن أفعل إذا واجهت هذا؟

Feeling sleepy, weak, or light-headed (these may continue into the following day)

لا تقود السيارة ولا تستخدم الأدوات أو الآلات. لا تشرب الكحول

Forgetfulness, feeling confused or unsteady

إذا أصبحت هذه الأمور مزعجة، تحدث مع طبيبك

Feeling (or being) aggressive

This can happen in some people - let your doctor know about it as soon as possible

Dependence

To help reduce the risk of this, your doctor will prescribe chlordiazepoxide for the shortest possible time

مهم: because of side-effects such as dizziness, muscle weakness and feeling sleepy or tired, taking this medicine may make you more likely to have a fall or an accident. Please take care, especially when getting up during the night or using stairs. Take extra care if you are frail, elderly or have any other risk factors for falls.

إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الدواء، يرجى التحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.

How to store chlordiazepoxide

  • احفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.

  • احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.

معلومات هامة عن جميع الأدوية

معلومات هامة عن جميع الأدوية

لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، اذهب إلى قسم الحوادث والطوارئ في مستشفى منطقتك فورًا. خذ العبوة معك، حتى لو كانت فارغة.

هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.

إذا اشتريت أي أدوية، تحقق مع الصيدلي من أنها آمنة لتناولها مع الأدوية الأخرى التي تتناولها.

لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.

إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.

الإبلاغ عن الآثار الجانبية لدواء أو لقاح

إذا واجهت آثارًا جانبية، يمكنك الإبلاغ عنها عبر الإنترنت من خلال موقع بطاقة صفراء.

مدقق الأعراض

غير متأكد من خلط الأدوية؟

تحقق من التفاعلات المحتملة بين الأدوية والمكملات الغذائية والأطعمة قبل تناولها معًا.

الأسئلة الشائعة

How does chlordiazepoxide help with anxiety?

Chlordiazepoxide works by influencing certain brain chemicals, called neurotransmitters, which are responsible for sending messages between brain cells. By affecting these substances, it produces a calming effect on different parts of the brain, which can help to ease anxiety symptoms.

Why is chlordiazepoxide only prescribed for short periods?

Chlordiazepoxide is typically prescribed for short durations, often just a few days, because prolonged use can lead to dependence. Additionally, your body can quickly get used to the medicine, and after a certain period, it may no longer be as effective in treating your condition.

What should I do if I feel aggressive while taking chlordiazepoxide?

If you experience feelings of aggression while taking chlordiazepoxide, it is important to inform your doctor about it as soon as possible, as this can happen in some individuals.

Can chlordiazepoxide cause problems with balance or coordination?

Yes, chlordiazepoxide can potentially affect your balance or coordination. Due to side-effects such as dizziness, muscle weakness, and feeling sleepy or tired, taking this medicine might increase your likelihood of falls or accidents. It's especially important to be careful when getting up at night or using stairs, particularly if you are frail, elderly, or have other risk factors for falls.

Is it safe to drive the day after taking chlordiazepoxide?

Chlordiazepoxide can affect your reactions and your ability to drive. The effects of the medicine can last into the following day. You should not drive until you are certain how you react to it, especially when you first start treatment. If you do drive and your ability is not impaired, it's advisable to carry proof of your prescription, such as a repeat prescription form or the patient information leaflet, as evidence that the medicine has been prescribed to you.

قراءة إضافية ومراجع

عن المؤلفعرض السيرة الذاتية الكاملة

صورة المؤلف

مايكل ستيوارت، MRPharmS

مدير مراجعة النشرات الطبية – متعاقد، صيدلي

بكالوريوس الصيدلة (مع مرتبة الشرف)، عضو الجمعية الملكية للصيادلة

مايكل هو صيدلي مجتمعي يمارس عمله في منطقة ميدلاندز وجنوب يوركشاير ولديه أكثر من 20 عامًا من الخبرة في تقديم المشورة بشأن الأدوية والحالات الطبية. لديه خلفية قوية في تدريب الرعاية الصحية، حيث قام بإنتاج وتقديم دورات تدريبية لفرق الصيدلة وموظفي دور الرعاية السكنية، بما في ذلك الممرضات. كما ساهم في مجالس استشارية للصيدلة لإدارة الحالات ذات الحدة المنخفضة في المجتمع.

حول المراجع

صورة المؤلف

سيد داجاني

تخرج سلطان دجاني من كلية الصيدلة في لندن عام 1994 وأصبح أصغر عضو منتخب في مجلس الجمعية الملكية للصيدلة منذ تأسيسها في عام 1842.

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