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Diloxanide tablets

Clinical author's note مايكل ستيوارت 19/03/2019: Diloxanide tablets were discontinued in the UK in June 2018. At the time of review there are no branded or generic products containing diloxanide available in the UK. Diloxanide may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

Diloxanide is used to treat an infection in your bowel.

Take one tablet every eight hours for 10 days.

If you have diarrhoea, drink plenty of fluids so that you don't become lacking in fluid in the body (dehydrated).

Even if you don't feel unwell, it is important that you complete the full course of tablets.


At a glance

  • Diloxanide is a medicine used to treat amoebiasis, an infection caused by a parasite.

  • Amoebiasis can cause diarrhoea and is spread through contaminated food or water.

  • You usually take one tablet three times a day for 10 days, even if you feel better.

  • Common side-effects can include feeling sick, tummy cramps, or having a skin rash.

  • Drink plenty of fluids to avoid dehydration and wash your hands thoroughly to prevent spreading the infection.

  • If you have other troublesome symptoms, speak to your doctor or pharmacist.

تابع القراءة أدناه

About diloxanide

نوع الدواء

An amoebicide

يستخدم لـ

Amoebiasis (in adults and in children over 12 years of age)

يُعرف أيضًا باسم

Diloxanide furoate

متوفر كـ

Tablets (discontinued), oral liquid medicine (special order)

Diloxanide is used to treat an infection caused by a very small living organism (amoeba) called Entamoeba histolytica (often shortened to E. histolytica).

Infection with the amoeba can occur after drinking water contaminated by infected stools (faeces) or eating food prepared or washed using contaminated water. Most people with amoebiasis do not develop any symptoms, but in those who do, diarrhoea is the most common symptom. People most at risk of amoebiasis include travellers to areas where infection with the amoeba is common, such as countries with poor sanitation.

Treatment for amoebiasis includes medication such as diloxanide to kill the organism, and drinking plenty of fluids to prevent lack of fluid in the body (dehydration).

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking diloxanide it is important that your doctor knows:

  • إذا كنت حاملاً أو مرضعة.

  • If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.

  • إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.

تابع القراءة أدناه

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about diloxanide, and will also provide you with a full list of the side-effects which you could experience from taking it.

  • Take the tablets exactly as your doctor tells you to. It is usual to take one tablet three times a day for 10 days. Space your doses out evenly throughout the day - so ideally, take one tablet every eight hours. You can take the tablets either with or without food.

  • Even if you feel well, keep taking the tablets until the course is finished (unless your doctor tells you to stop). If you forget to take a dose, take it as soon as you remember. Try to take the correct number of doses each day but do not take two doses at the same time to make up for a missed dose.

  • It is very important when you have diarrhoea that you drink plenty of fluids to prevent you from becoming lacking in fluid in the body (dehydrated). Your doctor will advise you about how much and what type of fluids you should drink.

  • Wash your hands thoroughly after going to the toilet. This will help to prevent the spread of the infection to others. Ideally, use liquid soap in warm running water, but any soap is better than none. Dry your hands properly after washing, and don't share towels or flannels with other people.

  • Regularly clean the toilets that you use with disinfectant. Keep a cloth just for cleaning the toilet (or use a disposable one each time). Remember to wipe the flush handle, toilet seat, bathroom taps and door handles at least once a day with hot water and detergent.

  • Be careful to wash your hands before preparing, serving, or eating your food. Don't prepare or serve food for others.

  • You should stay off work, school, college, etc, while you have amoebiasis. Your doctor will advise you when it is suitable for you to return. Avoid contact with other people as far as possible during this time.

تابع القراءة أدناه

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with diloxanide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Diloxanide side-effects

ماذا يمكنني أن أفعل إذا واجهت هذا؟

Feeling sick (nausea) or being sick (vomiting), loss of appetite, diarrhoea, tummy (abdominal) cramps, wind (flatulence)

التزم بالأطعمة البسيطة - تجنب الوجبات الغنية أو الحارة

Skin rash and itching, headache, dizziness

These are usually mild, but should they become troublesome, speak with your doctor

إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الأقراص، تحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.

  • احفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.

  • احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.

معلومات هامة عن جميع الأدوية

إذا كنت ستخضع لعملية جراحية أو علاج أسنان، أخبر الشخص الذي يقوم بالعلاج بالأدوية التي تتناولها.

إذا اشتريت أي أدوية، تحقق مع الصيدلي من أنها مناسبة لتناولها مع الأدوية الأخرى التي تتناولها.

لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، اذهب إلى قسم الحوادث والطوارئ في مستشفى منطقتك فورًا. خذ العبوة معك، حتى لو كانت فارغة.

هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.

لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.

إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.

MHRA - الإبلاغ عن التفاعلات الضارة

أبلغ عن الآثار الجانبية المشتبه بها للأدوية واللقاحات والسجائر الإلكترونية وحوادث الأجهزة الطبية والمنتجات المعيبة أو المزيفة (المزورة) إلى وكالة تنظيم الأدوية ومنتجات الرعاية الصحية لضمان الاستخدام الآمن والفعال.

symptom checker

غير متأكد من خلط الأدوية؟

تحقق من التفاعلات المحتملة بين الأدوية والمكملات الغذائية والأطعمة قبل تناولها معًا.

الأسئلة الشائعة

How does diloxanide work to treat amoebiasis?

Diloxanide is an amoebicide, which means it is a type of medicine specifically designed to kill the tiny living organism, Entamoeba histolytica, that causes amoebiasis. By targeting and eliminating this organism, diloxanide helps to clear the infection from the body.

Can I get amoebiasis from sources other than contaminated water or food?

The article states that infection with the amoeba can occur after drinking water contaminated by infected stools (faeces) or eating food prepared or washed using contaminated water. It does not mention other methods of transmission.

What should I do if I forget to take a dose of diloxanide?

If you forget a dose, take it as soon as you remember. You should try to take the correct number of doses each day, but importantly, do not take two doses at the same time to compensate for a missed dose.

Should I continue taking diloxanide if I start to feel better before the course is finished?

Yes, it is important to keep taking the tablets until the entire course is finished, even if you start to feel well. This ensures the infection is fully treated, unless your doctor specifically tells you to stop.

What precautions should I take to prevent spreading amoebiasis to others while I'm infected?

To prevent spreading the infection, you should wash your hands thoroughly after using the toilet, clean toilets regularly with disinfectant, wash hands before handling food, and avoid preparing or serving food for others. It's also advisable to stay off work, school, or college and limit contact with other people until your doctor advises it's safe to return.

What kind of symptoms should prompt me to contact my doctor regarding diloxanide side effects?

While some common side effects like feeling sick, loss of appetite, diarrhoea, tummy cramps, or wind often improve as your body adjusts, you should speak with your doctor or pharmacist if these continue or become troublesome. Additionally, if you experience a skin rash, itching, headache, or dizziness and they become bothersome, or if you notice any other symptoms you think might be due to the tablets, you should seek their advice.

Can children under 12 years old take diloxanide?

Diloxanide is used for amoebiasis in adults and in children over 12 years of age. This suggests it is not typically prescribed for children under this age.

قراءة إضافية ومراجع

تابع القراءة أدناه

About the authorView full bio

Author image

مايكل ستيوارت، MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

سيد داجاني

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

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