Rifabutin for infection

About rifabutin

Mycobacteria are a group of germs (bacteria) that can cause serious infections. Tuberculosis (TB) is a disease caused by one of the bacteria from this group, called Mycobacterium tuberculosis. TB usually affects the lungs.

Rifabutin is an antibiotic used to treat infections caused by mycobacteria. It is often prescribed for people with pulmonary TB. When prescribed in this way, it is usually prescribed as just one of a number of medicines to treat the infection. You may have been prescribed it for this reason. Alternatively, if your doctor thinks you might be at risk of a mycobacterial infection because your natural immunity has been lowered (such as if you have HIV), you will have been prescribed rifabutin as a preventative measure, to protect you from getting a mycobacterial infection.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking rifabutin it is important that your doctor knows:

• إذا كنتِ حاملاً، تحاولين الإنجاب أو تقومين بالرضاعة الطبيعية.

• إذا كان لديك أي مشاكل في كيفية عمل الكبد لديك، أو أي مشاكل في كيفية عمل الكلى لديك.

• If you have a rare inherited blood disorder caller porphyria.

• إذا كنت تتناول أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.

• إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about rifabutin and will provide you with a full list of the side-effects which you could experience from taking it.

• There are several ways rifabutin could be prescribed for you, depending upon the reason why you are taking it. Your doctor will tell you which way is right for you. It is المهم جدًا that you take rifabutin exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what the doctor said to you. As a guide:

  • To prevent infections, you will be asked to take two capsules every day.

  • To treat TB you will be asked to take one to three capsules every day.

  • To treat an infection (other than TB) you will be asked to take three or four capsules every day.

• You can take rifabutin at whatever time of day you find easiest to remember, but try to take your doses at the same time of day, each day. This will help you to remember to take your doses regularly. You can take rifabutin capsules either before or after meals.

• If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, leave out the forgotten dose from the previous day and take the dose that is due as normal. Do not take two doses together to make up for a missed dose.

• You must complete the full course of treatment (unless your doctor tells you otherwise) or your infection may come back. A course of treatment usually lasts for around six months. If you are taking rifabutin to prevent an infection, it is likely that you will be asked to take the capsules for the rest of your life.

• من المهم أن تحافظ على مواعيدك المنتظمة مع طبيبك. هذا لكي يتمكن طبيبك من متابعة تقدمك. قد يرغب طبيبك في إجراء بعض الفحوصات الدموية من وقت لآخر خلال العلاج للتأكد من أن دمك وكبدك يعملان بشكل صحيح.

• Rifabutin can cause your urine, sweat or skin to have an orange-reddish colour. This is completely harmless - it is nothing for you to worry about.

• If you wear soft contact lenses, please be aware that rifabutin can cause your lenses to become discoloured or stained. You may want to discuss this with your doctor or optician. An alternative type of contact lens may be more suitable for you, or alternatively, you may be advised to wear glasses instead.

• Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. The contraceptive effect of 'the pill', 'mini pill', contraceptive patches and vaginal rings is reduced by rifabutin and so these on their own are not suitable types of birth control.

• If you buy any medicines, check with a pharmacist that they are suitable for you to take. This is because rifabutin can interfere with a number of other medicines and stop them from working properly.

• Rifabutin can stop the oral typhoid vaccine from working as it should. If you are due to have any vaccinations, please make sure that the person treating you knows that you are taking this medicine.

• If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment that you are taking an antibiotic called rifabutin.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with rifabutin. You will find a full list in the manufacturer's information leaflet supplied with the medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الدواء، يرجى التحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.

• احفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.

• احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.