Trimethoprim for infections

About trimethoprim

Trimethoprim is given to treat a bacterial infection. It is mainly prescribed for urine infections, but it is also prescribed for chest infections and some other types of infection. It works by killing the germs (bacteria) responsible for the infection.

A urine infection is often called a urinary tract infection (UTI) by doctors. Most urine infections are caused by bacteria that come from your own bowel. They are usually easily treated with a short course of trimethoprim. Occasionally, longer-term treatment may be needed to prevent the infection from recurring.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking trimethoprim it is important that your doctor knows:

• إذا كنتِ حاملاً، تحاولين الإنجاب أو تقومين بالرضاعة الطبيعية.

• If you know you have low amounts of the vitamin folic acid.

• إذا كنت تواجه مشاكل في طريقة عمل كليتيك.

• إذا كنت تواجه مشاكل في طريقة عمل الكبد لديك.

• If you have a blood disorder, or if you have a rare inherited blood disorder called porphyria.

• إذا كنت تتناول أي أدوية أخرى. يشمل ذلك أي أدوية يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.

• إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about trimethoprim and will provide you with a full list of the side-effects which you could experience from taking it.

• Take trimethoprim tablets exactly as your doctor tells you to. Your dose will depend upon whether you are being treated because you have an infection, or to prevent an infection. As a guide, the dose for adults with an infection is 200 mg twice daily, taken morning and evening. The adult dose to prevent an infection is 100 mg at night. If trimethoprim has been prescribed for a child, it is likely that you will be supplied a liquid medicine - the dose will depend upon the age of the child, so read the directions on the label carefully to make sure you give the correct dose.

• Space your doses out evenly throughout the day - this means that tablets/medicine prescribed twice daily should be taken every 12 hours. Swallow the tablet with a drink of water. You can take trimethoprim either with or without food.

• Even if you feel your infection has cleared up, keep taking trimethoprim until the full course is finished (unless a doctor tells you to stop). This is to prevent the infection from coming back. A normal course of treatment is likely to last 3-14 days. The course will be for longer than this if you are taking trimethoprim to prevent recurrent infections.

• If you forget to take a dose at the correct time, take one as soon as you remember. Try to take the correct number of doses each day. Do not take two doses at the same time to make up for a forgotten dose.
  

• Most people improve within a few days of starting treatment. If your symptoms do not improve despite taking trimethoprim, go back to see your doctor, as you may need an alternative medicine. This is because some bacteria are resistant to some types of antibiotics.

• If you are taking the contraceptive 'pill' at the same time as this antibacterial medicine, the effectiveness of the 'pill' can be reduced if you have a bout of being sick (vomiting) or diarrhoea which lasts for more than 24 hours. If this should happen, ask your doctor or pharmacist for advice about what additional contraceptive precautions to use over the following few days. There is no need to use additional precautions for any bouts of sickness or diarrhoea which last for less than 24 hours.

• Trimethoprim can stop the oral typhoid vaccine from working. If you are due to have any vaccinations, make sure the person treating you knows that you are taking it.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with trimethoprim. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب هذا الدواء، تحدث مع طبيبك أو الصيدلي.

• احفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.

• احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.