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Danazol capsules

Clinical author's note مايكل ستيوارت 26/11/2024: Danol® capsules have been discontinued in the UK. At the time of review there are no licensed products containing danazol available in the UK. However danazol is available as a specially manufactured medicine or as an imported medicine. Products are still available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

Start taking danazol on the first day of your period unless you have been told otherwise. You can take the capsules either before or after meals.

It is important that you do not become pregnant while on danazol. Follow your doctor's advice about suitable contraception.

تابع القراءة أدناه

About danazol

نوع الدواء

A gonadotrophin inhibitor

يستخدم لـ

Endometriosis; breast cyst pain

يُعرف أيضًا باسم

Danol® (discontinued); Cyclomen® (in Canada)

متوفر كـ

كبسولات

Danazol works by altering the levels of some of your body's hormones. It is used to treat a number of different conditions.

الانتباذ البطاني الرحمي is a condition where tissue that normally lines the inside of your womb (uterus) is found elsewhere in your body, often in the pelvic area or abdomen. It can cause painful periods and persistent pain in the pelvic area, as well as other symptoms. By altering the levels of your hormones, danazol will help to relieve these symptoms.

Danazol is also prescribed to ease severe pain and tenderness associated with breast cyst disease (where other treatments have proved unhelpful). Breast cysts are small lumps which are found in the breast, but which are not cancerous.

In addition to the two conditions above, danazol is also prescribed by specialist doctors for people with a condition known as hereditary angio-oedema (although it is not licensed for this condition). If you have been prescribed it for this reason, please speak with your doctor if you have any questions about your treatment.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking danazol it is important that your doctor knows:

  • إذا كنتِ حاملاً، تحاولين الإنجاب أو تقومين بالرضاعة الطبيعية.

  • إذا كنت تعاني من حالة قلبية.

  • If you have any vaginal bleeding other than your regular period.

  • If you have ever had an unwanted blood clot (thrombosis), or stroke.

  • If you have any of the following conditions: epilepsy, diabetes (diabetes mellitus), high blood pressure, migraine, or a blood fat (lipid) disorder.

  • إذا كان لديك أي مشاكل في طريقة عمل الكبد لديك، أو أي مشاكل في طريقة عمل الكلى لديك.

  • If you have either of the following blood disorders: polycythaemia or porphyria.

  • If you know you have a type of cancer which is affected by hormones.

  • إذا كنت تتناول أو تستخدم أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.

  • إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.

تابع القراءة أدناه

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about danazol, and will also provide you with a full list of side-effects which you could experience from taking it.

  • You should start taking danazol on the first day of your next period unless you have been told otherwise.

  • Your doctor will tell you how many capsules to take each day, and when you should take them. As a guide, for the treatment of endometriosis or breast pain, danazol is usually taken 2-4 times daily for 3-6 months. Take the capsules exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what the doctor said to you.

  • Swallow the capsules whole with a drink of water - do not chew or open them before you swallow.

  • You can take danazol capsules either before or after meals, but try to take your doses at the same times each day, as this will help you to remember to take them regularly.

  • إذا نسيت تناول جرعة، فتناولها بمجرد أن تتذكر (إلا إذا كان الوقت قد اقترب لتناول الجرعة التالية، وفي هذه الحالة اترك الجرعة الفائتة). لا تتناول جرعتين معًا لتعويض الجرعة المنسية.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor may want you to have some blood tests during this treatment.

  • It is important that you do not become pregnant while you are on danazol. If appropriate, you and your partner should use a non-hormonal method of contraception, such as a condom. This is because hormonal methods (such as 'the pill' or 'mini pill') will not work. Speak with your doctor if you need further advice about what methods of contraception are suitable for you to use.

  • It is best not to drink alcohol while you are on danazol. This is because drinking alcohol while taking danazol could make you feel sick or short of breath.

تابع القراءة أدناه

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with danazol. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Danazol side-effects

ماذا يمكنني أن أفعل إذا واجهت هذا؟

الشعور بالغثيان (الدوار)، ألم في المعدة

التزم بالأطعمة البسيطة (تجنب الوجبات الغنية أو الحارة)

Feeling dizzy or tired, eyesight changes

If this happens, do not drive and do not use tools or machines while affected. Let your doctor know about any eyesight changes

الصداع، وآلام أخرى

Ask your pharmacist to recommend a suitable painkiller. If the headache is severe or continues, speak with your doctor

Increased growth of hair (particularly on your body or face), voice changes, hair loss similar to male baldness

تحدث مع طبيبك حول هذا في أسرع وقت ممكن. An alternative treatment may be more suitable for you

Acne, skin rash, muscle cramps, mood changes, changes in your desire for sex, increased appetite and weight changes, irregular menstrual periods, vaginal dryness and irritation, hot flushes, reduced breast size, a feeling that your heart is racing

إذا أصبحت أي من هذه الأمور مزعجة، تحدث مع طبيبك

مهم: if you experience any of the following rare but possibly serious symptoms, please speak with your doctor straightaway:

  • A severe headache and sickness (nausea and vomiting).

  • Any yellowing of your skin or of the whites of your eyes (jaundice).

  • Any painful swelling of your arms or legs, or sudden chest pain.

  • Any bruising that you can't explain. This could be a sign of a blood disorder.

إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الكبسولات، يرجى التحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.

  • احفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.

  • احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.

معلومات هامة عن جميع الأدوية

لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، اذهب إلى قسم الحوادث والطوارئ في مستشفى منطقتك فورًا. خذ العبوة معك، حتى لو كانت فارغة.

If you buy any medicines, always check with a pharmacist that they are suitable to take with your other medicines.

إذا كنت على وشك إجراء عملية جراحية أو أي علاج للأسنان، يرجى إخبار الشخص الذي يقوم بالعلاج بالأدوية التي تتناولها.

هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.

لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.

إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.

الإبلاغ عن الآثار الجانبية لدواء أو لقاح

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غير متأكد من خلط الأدوية؟

تحقق من التفاعلات المحتملة بين الأدوية والمكملات الغذائية والأطعمة قبل تناولها معًا.

قراءة إضافية ومراجع

تابع القراءة أدناه

About the authorView full bio

Author image

مايكل ستيوارت، MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

سيد داجاني

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

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