تخطي إلى المحتوى الرئيسي

هيدرالازين لعلاج ارتفاع ضغط الدم

Apresoline

Hydralazine is used to control high blood pressure (hypertension).

Treatment with hydralazine is usually long-term.

The most common side-effects are headaches and being aware of your heartbeat.

نظرة سريعة

  • Hydralazine is a medicine used to treat high blood pressure, often with other medicines.

  • It works by relaxing blood vessel walls, which lowers blood pressure.

  • It is usually taken twice a day, with or without food.

  • Common side-effects include headache and a fast heartbeat.

  • Tell your doctor if you have other conditions, especially heart or liver problems.

  • Do not stop taking hydralazine without speaking to your doctor.

About hydralazine

نوع الدواء

A vasodilator antihypertensive medicine

يستخدم لـ

The treatment of high blood pressure

يُعرف أيضًا باسم

Apresoline®

متوفر كـ

أقراص

Although many people with ارتفاع ضغط الدم (فرط ضغط الدم) do not feel unwell, it is still important that high blood pressure be treated. If left untreated, high blood pressure is a risk factor that can increase your chance of developing heart disease, a stroke, and other serious conditions. Hydralazine will be prescribed alongside other medicines to control high blood pressure.

Hydralazine works by relaxing the muscles in the walls of your blood vessels. This means that your blood vessels widen, which reduces your blood pressure and allows blood and oxygen to circulate more freely around your body. Hydralazine will only be prescribed for you if other treatments are not suitable or effective, as it can increase the amount of water and salt in your body and can increase your heart rate. The other medicines you are prescribed to take alongside it will help to control these side-effects.

Hydralazine is occasionally prescribed by hospital doctors for other heart conditions. If you have been prescribed it for a reason other than high blood pressure, speak with your doctor if you have any questions about your treatment.

Before taking hydralazine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking hydralazine it is important that your doctor knows:

  • If you have a condition called systemic lupus erythematosus. This is an inflammatory condition also called lupus, or SLE.

  • إذا كان لديك أي مشاكل في طريقة عمل الكبد لديك، أو إذا كان لديك أي مشاكل في طريقة عمل الكلى لديك.

  • If you have a problem with your blood vessels, such as coronary artery disease or cerebrovascular disease.

  • if you have a heart condition or have recently had a heart attack.

  • إذا كنت حاملاً أو مرضعة.

  • إذا كنت تعاني من اضطراب دم وراثي نادر يسمى البورفيريا.

  • إذا كنت تتناول أو تستخدم أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.

  • If you have ever had an allergic reaction to any medicine.

How to take hydralazine

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about hydralazine and will provide you with a full list of the side-effects which you could experience from taking the tablets.

  • Take hydralazine exactly as your doctor tells you to. It is usual to take one tablet twice a day. Try to take your doses at similar times of day each day, as this will help you to remember to take them regularly. There are two strengths of hydralazine tablet - it is usual to take the 25 mg strength tablet to begin with, but this may later be increased to the higher 50 mg strength tablet. Increasing your dose gradually allows your doctor to make sure that you have the dose that best helps your condition, but also keeps unwanted side-effects to a minimum.

  • Swallow the tablet whole with a drink of water. You can take hydralazine either with or without food.

  • If you forget to take a dose at your usual time, take it as soon as you remember unless your next dose is due. If your next dose is due then take the dose which is due but leave out the forgotten one. Do not take two doses together to make up for a missed dose.

تحقيق أقصى استفادة من علاجك

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have regular blood pressure measurements, and also some blood and urine tests from time to time.

  • Your doctor will advise you on what lifestyle changes you can make to help your condition. These could include losing weight if you are overweight, taking regular physical activity, eating a healthy diet, cutting back on the amount of alcohol you drink, stopping smoking, and reducing the amount of salt in your meals and caffeine in your drinks. It is important that you follow any advice you are given.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take. This is because some medicines (particularly some anti-inflammatory painkillers) can interfere with the way hydralazine works.

  • Treatment with hydralazine is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise by your doctor.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking hydralazine. This is because some anaesthetics can affect your blood pressure.

Can hydralazine cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with hydralazine. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common

hydralazine side-effects

(هذه تؤثر على أكثر من 1 من كل 10 أشخاص)

ماذا يمكنني أن أفعل إذا واجهت هذا؟

صداع

اشرب الكثير من الماء واطلب من الصيدلي أن يوصي بمسكن مناسب للألم. إذا استمرت الصداع، تحدث مع طبيبك

A fast heartbeat, the sensation of having a 'thumping heart' (palpitations)

If you are concerned, speak with your doctor

Common

hydralazine side-effects

(تؤثر هذه على أقل من 1 من كل 10 أشخاص)

ماذا يمكنني أن أفعل إذا واجهت هذا؟

Feeling flushed, swollen feet or ankles, chest pain

If any of these symptoms continue or cause you concern, speak with your doctor

الشعور بالدوار

If this happens, sit down for a while until you feel better. Do not drive and do not use tools or machines while affected. Do not drink alcohol

الشعور بالغثيان (الدوار) أو التقيؤ (القيء)، الإسهال

Eat simple meals and drink plenty of water to replace lost fluids

Joint or muscle pain

Speak with your doctor about this as soon as possible. It may be an early sign of systemic lupus erythematosus-like syndrome

إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الأقراص، يرجى التحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.

How to store hydralazine

  • احفظ جميع الأدوية بعيدًا عن متناول الأطفال وأنظارهم.

  • احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.

معلومات هامة عن جميع الأدوية

معلومات هامة عن جميع الأدوية

لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، اذهب إلى قسم الحوادث والطوارئ في مستشفى منطقتك. خذ العبوة معك، حتى لو كانت فارغة.

هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.

Do not keep-out-of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.

إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.

الإبلاغ عن الآثار الجانبية لدواء أو لقاح

إذا واجهت آثارًا جانبية، يمكنك الإبلاغ عنها عبر الإنترنت من خلال موقع بطاقة صفراء.

مدقق الأعراض

غير متأكد من خلط الأدوية؟

تحقق من التفاعلات المحتملة بين الأدوية والمكملات الغذائية والأطعمة قبل تناولها معًا.

الأسئلة الشائعة

What should I do if I accidentally take too much hydralazine?

If you suspect that you or someone else might have taken an overdose of hydralazine, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty.

Why would hydralazine be prescribed for conditions other than high blood pressure?

While primarily used for high blood pressure, hospital doctors sometimes prescribe hydralazine for other heart conditions. If you've been prescribed it for a reason other than high blood pressure, consult your doctor for clarification about your specific treatment.

Can I stop taking hydralazine once my blood pressure improves?

Treatment with hydralazine is usually long-term. You should continue to take the tablets exactly as prescribed unless your doctor advises you otherwise. Do not stop taking it without your doctor's guidance.

Are there any specific activities I should avoid while taking hydralazine?

If you experience dizziness, which can be a common side-effect, you should sit down until you feel better. While affected by dizziness, it's important not to drive, operate tools, or use machinery. You should also avoid drinking alcohol as it can worsen dizziness.

Can hydralazine affect other medicines I'm taking, even non-prescription ones?

Yes, some medicines can interfere with how hydralazine works. This includes specific medicines available without a prescription, such as some anti-inflammatory painkillers, as well as herbal and complementary medicines. Always check with a pharmacist to ensure any new medicine you buy is suitable for you.

قراءة إضافية ومراجع

عن المؤلفعرض السيرة الذاتية الكاملة

صورة المؤلف

مايكل ستيوارت، MRPharmS

مدير مراجعة النشرات الطبية – متعاقد، صيدلي

بكالوريوس الصيدلة (مع مرتبة الشرف)، عضو الجمعية الملكية للصيادلة

مايكل هو صيدلي مجتمعي يمارس عمله في منطقة ميدلاندز وجنوب يوركشاير ولديه أكثر من 20 عامًا من الخبرة في تقديم المشورة بشأن الأدوية والحالات الطبية. لديه خلفية قوية في تدريب الرعاية الصحية، حيث قام بإنتاج وتقديم دورات تدريبية لفرق الصيدلة وموظفي دور الرعاية السكنية، بما في ذلك الممرضات. كما ساهم في مجالس استشارية للصيدلة لإدارة الحالات ذات الحدة المنخفضة في المجتمع.

حول المراجع

صورة المؤلف

سيد داجاني

تخرج سلطان دجاني من كلية الصيدلة في لندن عام 1994 وأصبح أصغر عضو منتخب في مجلس الجمعية الملكية للصيدلة منذ تأسيسها في عام 1842.

تاريخ المقال

تمت كتابة المعلومات على هذه الصفحة ومراجعتها من قبل أطباء مؤهلين.

  • المراجعة التالية مستحقة: 11 يونيو 2027
  • 12 ديسمبر 2022 | أحدث إصدار

    آخر تحديث بواسطة

    مايكل ستيوارت، MRPharmS

    مراجعة من قبل

    سيد داجاني
أداة التحقق من أهلية لقاح الإنفلونزا

اسأل، شارك، تواصل.

تصفح المناقشات، اطرح الأسئلة، وشارك التجارب عبر مئات المواضيع الصحية.

اشترك في النشرة الإخبارية للمرضى

جرعتك الأسبوعية من النصائح الصحية الواضحة والموثوقة - مكتوبة لمساعدتك على الشعور بالاطلاع والثقة والتحكم.

يرجى إدخال عنوان بريد إلكتروني صالح

من خلال الاشتراك، فإنك تقبل سياسة الخصوصية. يمكنك إلغاء الاشتراك في أي وقت. نحن لا نبيع بياناتك أبدًا.