Ivabradine tablets
Procoralan
مراجعة من قبل Sid Dajaniآخر تحديث بواسطة Michael Stewart, MRPharmSLast updated 10 ديسمبر 2024
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Take two doses a day - take the first dose in the morning with your breakfast, and the second dose with your evening meal.
The most common side-effect is seeing flashes of colour (or haloes) caused by sudden changes in light intensity. Please take extra care when using tools or machines and when driving.
At a glance
Ivabradine is a medicine used to prevent angina pain and treat heart failure.
It works by slowing down your heart rate, which reduces the heart's need for oxygen.
Take ivabradine twice daily with food, exactly as your doctor prescribes.
Avoid or limit grapefruit juice as it can increase the medicine's effects.
Common side effects include vision changes and dizziness; do not drive if affected.
في هذه المقالة:
Video picks for علاج ووقاية من أمراض القلب
تابع القراءة أدناه
About ivabradine
نوع الدواء | A selective sinus node Iالأ inhibitor |
يستخدم لـ | To prevent angina pain; heart failure |
يُعرف أيضًا باسم | Procoralan® |
متوفر كـ | أقراص |
الذبحة الصدرية is a pain that comes from the heart. It is usually caused by the narrowing of one or more of the arteries that supply blood to your heart. This narrowing reduces the blood supply to parts of your heart muscle. When your heart needs more blood and oxygen than it can get through the narrowed arteries (for example, when you walk fast or climb stairs), you feel angina pain.
فشل القلب is a condition where your heart does not pump as effectively as it once did. This causes problems getting blood and oxygen to the rest of your body.
Ivabradine works by slowing down your heart rate a little. Because your heart is working less quickly, the amount of oxygen your heart needs is reduced. If you have been prescribed ivabradine to prevent angina, this will help to reduce the number of angina attacks you have. It also means that your heart needs to do less work to pump blood around your body if you have heart failure.
Before taking ivabradine
العودة إلى المحتوياتSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking ivabradine it is important that your doctor knows:
إذا كنت حاملاً أو مرضعة.
If you know you have a slow or irregular heart rhythm.
If you know you have low blood pressure.
If you have a pacemaker fitted.
If you have recently had a stroke or a heart attack.
If you have a problem with the retina of your eye.
إذا كان لديك أي مشاكل في طريقة عمل الكبد لديك، أو أي مشاكل في طريقة عمل الكلى لديك.
إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.
إذا كنت تتناول أو تستخدم أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.
تابع القراءة أدناه
How to take ivabradine
العودة إلى المحتوياتBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about ivabradine and will also provide you with a full list of side-effects which you could experience from taking it.
Take ivabradine exactly as your doctor tells you to. It is usual to take a dose twice daily, one in the morning and the other in the evening. When starting your treatment, your doctor may give you a small dose (such as half of a 5 mg tablet) and then increase it after a short while. This will help avoid any unwanted side-effects, particularly dizziness. There are two strengths of tablet available - 5 mg and 7.5 mg. Your doctor will tell you which is right for you to continue treatment with.
Try to take your doses at the same times of day each day, as this will help you to remember to take ivabradine regularly. Take the tablet during a meal with a drink of water. Do not chew or crush the tablets.
If you forget to take a dose at your usual time, take it when you remember. However, if it is nearly time to take your next dose when you remember, then leave out the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a missed dose.
تحقيق أقصى استفادة من علاجك
العودة إلى المحتوياتIvabradine tablets are not suitable to take to relieve pain if you are having an angina attack. Your doctor will also prescribe a nitrate medicine, such as glyceryl trinitrate (GTN), for you to take if this happens. If after using GTN your pain has not eased within a few minutes, call for an ambulance.
Try to keep your regular appointments with your doctor. This is so your doctor can monitor your progress and check your heart rate.
It is best to avoid or limit the amount of grapefruit juice you drink while you are on ivabradine. This is because a chemical in grapefruit juice increases the amount of ivabradine in your bloodstream. This makes side-effects more likely.
If you buy any medicines 'over the counter', please check with a pharmacist that they are suitable for you to take with your prescribed medicines.
إذا كنت على وشك إجراء عملية جراحية أو أي علاج للأسنان، يرجى إخبار الشخص الذي يقوم بالعلاج بالأدوية التي تتناولها.
تابع القراءة أدناه
Can ivabradine cause problems?
العودة إلى المحتوياتAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with ivabradine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common ivabradine side-effects (these affect more than 1 in 10 people) | ماذا يمكنني أن أفعل إذا واجهت هذا؟ |
Difficulties with changes in light, blurred vision | Do not drive (especially at night) and do not use tools or machines until you know how you react |
Common ivabradine side-effects (these affect fewer than 1 in 10 people) | ماذا يمكنني أن أفعل إذا واجهت هذا؟ |
Feeling dizzy (possibly due to a slow heart rate) | If this happens, do not drive and do not use tools or machines while affected. Let your doctor know so that your heart rate can be checked |
صداع | This is common when you first start ivabradine but it should soon settle down. In the meantime, ask your doctor or pharmacist to recommend a suitable painkiller |
إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الأقراص، تحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.
How to store ivabradine
العودة إلى المحتوياتاحفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.
احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.
معلومات هامة عن جميع الأدوية
العودة إلى المحتوياتمعلومات هامة عن جميع الأدوية
لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، توجه إلى قسم الحوادث والطوارئ في مستشفى منطقتك. خذ العبوة معك، حتى لو كانت فارغة.
هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.
لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.
إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.
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غير متأكد من خلط الأدوية؟
تحقق من التفاعلات المحتملة بين الأدوية والمكملات الغذائية والأطعمة قبل تناولها معًا.
الأسئلة الشائعة
What is the main purpose of ivabradine?
Ivabradine is used to either prevent angina pain or to help manage heart failure. In angina, it reduces the heart's oxygen demand by slowing the heart rate, decreasing the frequency of angina attacks. In heart failure, it helps the heart pump blood more efficiently by making it work less quickly.
How does Ivabradine actually slow down my heart rate?
Ivabradine works by targeting a specific mechanism in your heart called the 'sinus node'. By acting as a selective sinus node If inhibitor, it directly influences the electrical impulses that control your heart rate, causing it to beat a little more slowly.
Can I take ivabradine if I already have other health conditions?
Before starting ivabradine, it's crucial for your doctor to know about any existing health issues. This includes if you have a slow or irregular heart rhythm, low blood pressure, a pacemaker, recent stroke or heart attack, problems with your eye's retina, or any liver or kidney problems. This helps ensure the medication is safe and appropriate for you.
What should I do if I experience blurred vision or dizziness from ivabradine?
If you experience difficulties with changes in light or blurred vision, especially at night, do not drive or use tools or machines until you know how you react to the medicine. If you feel dizzy, which might be due to a slow heart rate, similarly avoid driving or operating machinery and inform your doctor so your heart rate can be checked.
Does ivabradine interact with any foods or drinks?
Yes, it's advised to avoid or limit grapefruit juice while taking ivabradine. A chemical in grapefruit juice can increase the amount of ivabradine in your bloodstream, making side-effects more likely.
Is it safe to take ivabradine if I am pregnant or breastfeeding?
It is very important to tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding. Some medicines are not suitable in these circumstances, and your doctor will need this information to ensure ivabradine is appropriate for you.
What should I do if I forget a dose of ivabradine?
If you forget a dose, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed dose and just take your next dose at the scheduled time. Never take two doses at once to make up for a forgotten one.
Can ivabradine be used to stop an angina attack once it's started?
No, ivabradine tablets are not designed to relieve pain during an angina attack. For sudden angina pain, your doctor will prescribe a different type of medicine, such as glyceryl trinitrate (GTN). If your pain doesn't ease after using GTN within a few minutes, you should call for an ambulance.
قراءة إضافية ومراجع
- Manufacturer's PIL, Procoralan® 5 mg and 7.5 mg tablets; Servier Laboratories Limited, The electronic Medicines Compendium. Dated July 2024.
- الأدوية كاملة BNF الطبعة 89; الجمعية الطبية البريطانية والجمعية الملكية الصيدلانية لبريطانيا العظمى، لندن.
تابع القراءة أدناه
About the authorView full bio

مايكل ستيوارت، MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

سيد داجاني
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
تاريخ المقال
تمت كتابة المعلومات على هذه الصفحة ومراجعتها من قبل أطباء مؤهلين.
المراجعة التالية مستحقة: 10 ديسمبر 2027
10 ديسمبر 2024 | أحدث إصدار

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