Perampanel for epilepsy

About perampanel for epilepsy

Perampanel is used alongside other medicines in the treatment of seizures. A seizure is a short episode of symptoms which is caused by a burst of abnormal electrical activity in the brain. Generalised seizures occur if you have a burst of abnormal electrical activity which spreads throughout the brain. Generalised seizures affect consciousness and may cause a convulsion. With a focal seizure, the burst of electrical activity stays in one part of the brain and therefore you tend to have localised or 'focal' symptoms. Because different parts of the brain control different functions, your symptoms will depend on which part of your brain is affected. Focal seizures can sometimes develop into seizures which affect all of your brain. These are called secondary generalised seizures.

Perampanel is prescribed alongside other anti-epileptic medicines. It works by stabilising the electrical activity in your brain.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking perampanel it is important that your doctor knows:

• إذا كنتِ حاملاً، تحاولين الإنجاب أو تقومين بالرضاعة الطبيعية.

• إذا كان لديك أي مشاكل في طريقة عمل الكبد لديك، أو في طريقة عمل الكلى لديك.

• إذا كنت تتناول أو تستخدم أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.

• إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about perampanel, and it will also provide you with a full list of the side-effects which you could experience from taking it.

• Take perampanel exactly as your doctor tells you to. You will be asked to take a low dose when you first start taking it, and then your dose will be increased as your body gets used to it. Your doctor or pharmacist will explain this to you, and directions will also be printed on the label of the pack to remind you about what the doctor said to you.

• Perampanel is taken as a once-daily dose at bedtime. Try to avoid missing any doses. If you do forget, just take your next dose when it is due - do not take two doses together to make up for a forgotten dose.

• Swallow the tablet whole with a drink of water. Do not chew, break or crush the tablet.

• If you (or your child) have been prescribed the oral liquid medicine, follow the manufacturer's instructions for using the oral syringe.

• Perampanel can be taken with or without food.

• There are several strengths of perampanel tablets and each strength is a different colour. When you collect a new supply, check to make sure they are the colour you are expecting. If not, ask your pharmacist to check it out for you.
  

• حاول الحفاظ على مواعيدك المنتظمة مع طبيبك. هذا لكي يتمكن طبيبك من متابعة تقدمك.

• عند البدء في علاج جديد للصرع، قد يحدث تغيير في عدد أو نوع النوبات التي تعاني منها. سيقوم طبيبك بإرشادك حول هذا الأمر.

• Perampanel could make you feel sleepy, especially when you first start treatment.

• أثناء تلقيك العلاج من الصرع، هناك خطر صغير بأن تتطور لديك تغييرات في المزاج، أفكار مزعجة ومشاعر حول الانتحار. إذا حدث ذلك، يجب عليك إبلاغ طبيبك على الفور.

• People with epilepsy must stop driving at first. Your doctor will advise you about if and when it may be possible for you to resume driving again.

• Drinking alcohol while you are on perampanel can increase the risk of side-effects and may not be recommended for you. Ask for your doctor's advice.

• Many anti-epileptic medicines can harm an unborn child. If you are a woman, make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. If you want to have a family, discuss this with your doctor so that you can be given advice from a specialist قبل you become pregnant.

• You need to take perampanel regularly every day. Do not stop taking it unless your doctor tells you to stop. Stopping treatment suddenly can cause problems and your doctor will want you to reduce your dose gradually if this becomes necessary.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with perampanel. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الأقراص، تحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.

• احفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.

• احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.

• The oral liquid medicine lasts for 90 days after first opening. It's a good idea to write the date you opened the bottle on to the label.