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Clinical author's note

مايكل ستيوارت 24/08/2024: Treosulfan 250 mg capsules have been discontinued in the United Kingdom. At the time of review there are no branded or generic tablets or capsules containing treosulfan available in the UK. Treosulfan is still available as a solution for infusion, administered in hospital. The information in this leaflet may still be relevant if you are being treated with treosulfan infusions. Please read the information given to you by your hospital and refer to any manufacturer's information supplied with your medicine.

Treosulfan will be prescribed for you by a specialist doctor.

Please keep your regular appointments with your doctor or hospital. You will need to have frequent blood tests.

If you think you are getting an infection or if you have a high temperature, please see your doctor straightaway.

At a glance

  • Treosulfan is a chemotherapy medicine used to treat ovarian cancer.

  • It is given as an injection, but used to be available as capsules.

  • Treosulfan prevents cancer cells from multiplying.

  • You will need regular blood tests and check-ups during treatment.

  • Drink plenty of fluids to help prevent a serious type of cystitis.

  • If you develop a sore throat or a fever, contact your doctor straight away.

  • Do not get immunisations without talking to your specialist doctor first.

تابع القراءة أدناه

About treosulfan

نوع الدواء

An alkylating chemotherapy medicine

يستخدم لـ

Cancer of the ovaries

متوفر كـ

Capsules (discontinued) and injection

Treosulfan is used to treat ovarian cancer in women. In cancer, certain cells in your body grow and multiply too fast. Chemotherapy medicines like treosulfan work by preventing cells from multiplying. This reduces the number of cancer cells made.

Treosulfan may be given alongside other medicines or treatments to help treat your condition.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking treosulfan it is important that your doctor knows:

  • إذا كنت حاملاً أو مرضعة.

  • If you have an infection or feel unwell.

  • If you have a rare inherited blood condition called porphyria.

  • إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.

  • إذا كنت تتناول أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.

تابع القراءة أدناه

  • Before you start this treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet. These will give you more information about treosulfan and will provide you with a full list of the side-effects which you may experience from having treatment.

  • Treosulfan will be prescribed for you by a specialist doctor who is experienced in treating your condition.

  • While you are having treosulfan treatment, it is important that you drink plenty of fluid and that you pass urine frequently. Drinking lots of water and other fluids will help prevent a serious type of cystitis sometimes caused by this medicine.

  • You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests and check-ups during your treatment with treosulfan.

  • While you are having treosulfan and for six months after you have stopped the treatment, do not have any immunisations (vaccinations) without talking to your specialist doctor first. Treosulfan lowers your body's resistance and there is a risk that you will get an infection from some vaccines.

  • It is important that you do not get pregnant while you are having treosulfan. If appropriate, please discuss with your doctor which types of contraception are suitable for you and your partner.

تابع القراءة أدناه

Medicines used to treat cancer can have a number of side-effects, some of which can be delayed for several days or weeks after taking the medicine. Most chemotherapy medicines can lower the number of white cells in your blood, which increases the risk of you getting an infection. While you are taking treosulfan you should take precautions to reduce the risk of getting an infection - you can do this by avoiding being with people who you know have an infection. If you think you are getting a sore throat or if you have a high temperature, please let your doctor know as soon as possible so that you can get some treatment straightaway.

Your doctor will discuss with you the possibility of unwanted side-effects from your treatment, although not everyone experiences these. The table below contains some of the side-effects associated with treosulfan. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Please let your doctor know if you experience any of the following:

Very common treosulfan side-effects (these affect more than 1 in 10 women)

ماذا يمكنني أن أفعل إذا واجهت هذا؟

A high temperature (fever), or symptoms of an infection

Let your doctor know about this straightaway

الشعور بالغثيان (الغثيان) أو التقيؤ (القيء)

Stick to simple meals - avoid rich or spicy food. If this becomes troublesome, let your doctor know, as you can be prescribed an anti-sickness medicine

Some loss of hair; a bronze skin colouration

Discuss these with your doctor if you are concerned

Rare treosulfan side-effects

ماذا يمكنني أن أفعل إذا واجهت هذا؟

A burning feeling as you pass urine, blood in your urine

Continue to drink plenty of water and try to pass urine frequently. If you notice blood in your urine, please let your doctor know straightaway

Feeling short of breath

Let your doctor know about this straightaway. It could be a sign of a rare but serious lung condition

إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الكبسولات، يرجى التحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.

  • احفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.

  • احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.

معلومات هامة عن جميع الأدوية

لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، اذهب إلى قسم الحوادث والطوارئ في مستشفى منطقتك. خذ العبوة معك، حتى لو كانت فارغة.

هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.

إذا كنت ستخضع لعملية جراحية أو علاج أسنان، أخبر الشخص الذي يقوم بالعلاج بالأدوية التي تتناولها.

If you buy any medicines, always check with a pharmacist that they are suitable for you to take with your prescribed medicines.

لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.

إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.

الإبلاغ عن الآثار الجانبية لدواء أو لقاح

إذا واجهت آثارًا جانبية، يمكنك الإبلاغ عنها عبر الإنترنت من خلال Yellow Card website.

symptom checker

غير متأكد من خلط الأدوية؟

تحقق من التفاعلات المحتملة بين الأدوية والمكملات الغذائية والأطعمة قبل تناولها معًا.

الأسئلة الشائعة

What is treosulfan typically used for in cancer treatment?

Treosulfan is specifically used to treat ovarian cancer in women. It is a chemotherapy medicine that tackles cancer by stopping cells from multiplying too fast, which helps to reduce the number of cancer cells being produced.

Are there any specific activities I should avoid while taking treosulfan?

Yes, while on treosulfan and for six months after stopping the treatment, you should avoid having any immunisations without first speaking to your specialist doctor. This is because treosulfan lowers your body's resistance and increases the risk of infection from some vaccines. Additionally, it's crucial to avoid becoming pregnant during treatment.

What should I do if I experience a high temperature or symptoms of infection while on treosulfan?

If you develop a high temperature, experience symptoms of an infection, or think you are getting a sore throat, you should let your doctor know straightaway. Treosulfan can lower your white blood cell count, increasing your risk of infection, so prompt medical attention is important.

How can I manage feeling sick or vomiting due to treosulfan?

If you experience feeling sick (nausea) or being sick (vomiting), try to stick to simple meals and avoid rich or spicy food. If these symptoms become troublesome, inform your doctor, as they may be able to prescribe anti-sickness medicine to help.

What should I do if I notice a burning sensation or blood in my urine?

If you experience a burning feeling when you pass urine or notice blood in your urine, continue to drink plenty of water and try to pass urine frequently. You should also let your doctor know about these symptoms straightaway, especially if you see blood in your urine.

Why is it important to drink plenty of fluids while on treosulfan treatment?

Drinking plenty of fluids and passing urine frequently is very important while you are having treosulfan treatment. This helps to prevent a serious type of cystitis, which can sometimes be caused by this medicine.

Do I need to worry about hair loss or changes in skin colour with treosulfan?

Some loss of hair and a bronze skin colouration are listed as very common side-effects of treosulfan. If these are a concern for you, you should discuss them with your doctor.

قراءة إضافية ومراجع

تابع القراءة أدناه

About the authorView full bio

Author image

مايكل ستيوارت، MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

سيد داجاني

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

تاريخ المقال

تمت كتابة المعلومات على هذه الصفحة ومراجعتها من قبل أطباء مؤهلين.

  • المراجعة التالية مستحقة: 25 أغسطس 2027
  • 23 Aug 2024 | أحدث إصدار

    آخر تحديث بواسطة

    مايكل ستيوارت، MRPharmS

    مراجعة من قبل

    سيد داجاني
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