Alogliptin tablets for diabetes

About alogliptin

Insulin is a hormone which is made naturally in your body. It helps to control the levels of sugar (glucose) in your blood. If your body does not make enough insulin, or if it does not use the insulin it makes effectively, this results in the condition called داء السكري.

People with diabetes need treatment to control the amount of sugar in their blood. This is because good control of blood sugar levels reduces the risk of complications later on. Some people can control the sugar in their blood by making changes to the food they eat but, for other people, medicines like alogliptin are given alongside the changes in diet.

Alogliptin works in part by increasing the amount of insulin produced by your body, which then controls the level of sugar in your blood. It also reduces the amount of a substance called glucagon being produced by your pancreas. Glucagon causes your liver to produce more sugar; so, by reducing the amount of glucagon in your body, this also helps to reduce the levels of sugar in your blood.

For more information on how antidiabetic medicines like alogliptin work, see the separate leaflet called Treatments for type 2 diabetes.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking alogliptin it is important that your doctor knows:

• إذا كنت حاملاً أو مرضعة.

• If you have ever had an inflamed pancreas (pancreatitis).

• If you have heart failure, a condition where your heart is not working as well as it should.

• إذا كان لديك أي مشاكل في طريقة عمل الكبد لديك، أو إذا كان لديك أي مشاكل في طريقة عمل الكلى لديك.

• إذا كنت تتناول أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.

• إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about alogliptin and will provide you with a full list of the side-effects which you may experience from taking it.

• Take alogliptin tablets exactly as your doctor tells you to. Your dose will be on the label of the pack to remind you about what the doctor said to you.

• If you are taking a brand of alogliptin tablets called Vipidia®, the dose for most people is 25 mg (one tablet) daily. It will, however, be different to this if you have any problems with the way your kidneys work. You can generally take alogliptin at a time of day to suit you, but it is best to take your doses at the same time of day each day. Swallow the tablet with a drink of water - you can take it either with or without food.

• If you have been prescribed a combination tablet of alogliptin with metformin (Vipdomet® brand) you should take one tablet twice a day. Take the tablet after you have eaten a meal or with a snack, as this will help to reduce the chance of an upset stomach. There are two strengths of Vipdomet® tablet - both strengths contain the same amount of alogliptin but the amount of metformin differs. You will be prescribed the strength of tablet that fits with your current metformin dose.

• إذا نسيت تناول جرعة، فتناولها بمجرد أن تتذكر (إلا إذا كان الوقت قد اقترب لتناول الجرعة التالية، وفي هذه الحالة اترك الجرعة الفائتة). لا تتناول جرعتين معًا لتعويض الجرعة المنسية.

• It is important that you keep your regular doctor's and clinic appointments. This is so that your progress can be monitored. You will need regular check-ups with an eye clinic and a foot clinic as well as with your doctor and diabetes clinic.

• قد يوصي طبيبك بإجراء اختبار للسكر (الجلوكوز) في دمك أو بولك بانتظام للتأكد من أن مرض السكري لديك تحت السيطرة. سيقوم طبيبك أو ممرض السكري بتعليمك كيفية القيام بذلك.

• إذا كنت قد تلقيت نصيحة من طبيبك بشأن تغييرات في نظامك الغذائي، أو الإقلاع عن التدخين، أو ممارسة التمارين الرياضية بانتظام، فمن المهم أن تتبع النصيحة التي تلقيتها.

• لا تشرب الكحول، لأنه يمكن أن يؤثر على التحكم في مستوى السكر في الدم. اسأل طبيبك إذا كنت بحاجة إلى مزيد من النصائح حول هذا الموضوع.

• إذا كنت سائقًا، يجب أن تأخذ حذرك بشكل خاص، حيث قد تتأثر قدرتك على التركيز إذا لم يكن مرض السكري لديك تحت السيطرة الجيدة. قد يُنصح بفحص مستويات السكر في الدم قبل السفر واصطحاب وجبة خفيفة معك في الرحلات الطويلة.

• استشر طبيبك قبل البدء في أي تمرين بدني جديد، حيث سيكون لذلك تأثير على مستويات السكر في الدم وقد تحتاج إلى فحص مستويات الدم أو البول بشكل أكثر انتظامًا.

• Make sure you know what it feels like if your blood sugar is low. This is known as hypoglycaemia, or a 'hypo'. Although alogliptin is unlikely to cause low blood sugar, other medicines that you are taking for diabetes alongside it may. The first signs of hypoglycaemia are feeling shaky or anxious, sweating, looking pale, feeling hungry, having a feeling that your heart is pounding (palpitations), and feeling dizzy.

• If you are due to have an operation or dental treatment, you should tell the person carrying out the treatment that you have diabetes and that you are taking alogliptin.

• If you become unusually thirsty, pass urine more frequently than normal, and feel very tired, you should let your doctor know. These are signs that there is too much sugar in your blood and your treatment may need adjusting.

• Treatment for diabetes is usually lifelong. Continue to take alogliptin tablets unless you are advised otherwise by your doctor.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with alogliptin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الأقراص، تحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.

• احفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.

• احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.