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Zavedos
مراجعة من قبل Sid Dajaniآخر تحديث بواسطة Michael Stewart, MRPharmSLast updated 19 يونيو 2023
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Swallow idarubicin capsules whole with a drink of water - do not bite, chew or suck the capsules.
Idarubicin may colour your urine red. This is nothing to worry about and will disappear after a day or two.
Keep your regular appointments with your doctor or hospital. You will need to have frequent blood tests and check-ups.
The most common side-effects are diarrhoea, feeling sick (nausea), sore mouth, and an increased risk of infection.
At a glance
Idarubicin is a chemotherapy medicine used to treat leukaemia and breast cancer.
It stops cancer cells from growing and dividing in the body.
It is available as capsules or an injection.
Take capsules whole with water; do not open or chew them.
Regular blood tests and check-ups are needed during treatment.
You must avoid pregnancy while taking idarubicin and for a period after.
A common side-effect is that your urine may temporarily turn red.
في هذه المقالة:
Video picks for علاج السرطان والأدوية
تابع القراءة أدناه
About idarubicin
نوع الدواء | An anthracycline chemotherapy medicine |
يستخدم لـ | Treatment of leukaemia and breast cancer |
يُعرف أيضًا باسم | Zavedos® |
متوفر كـ | Capsules and injection |
Idarubicin is used to treat some cancers. It is given in particular to treat اللوكيميا, which is cancer of white blood cells. It is also given for سرطان الثدي if other treatments have not proved effective. It can be used alone or alongside other medicines for the treatment of cancer.
In cancer, certain cells in the body grow and multiply too fast. أدوية العلاج الكيميائي (مضادة للسرطان) like idarubicin work by preventing the growth and division of cells, and this reduces the number of cancer cells your body makes. Idarubicin is usually given as an injection but it can also be taken by mouth in the form of capsules. This leaflet provides information about idarubicin capsules.
Before taking idarubicin
العودة إلى المحتوياتSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking idarubicin it is important that your doctor or pharmacist knows:
إذا كنت حاملاً أو مرضعة.
إذا كان لديك أي مشاكل في طريقة عمل الكبد لديك، أو في طريقة عمل الكلى لديك.
If you have an infection or feel unwell.
If you have a heart condition, such as if you have had a heart attack in the past or if you have an unusual heartbeat.
إذا كنت تتناول أو تستخدم أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.
إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.
تابع القراءة أدناه
How to take idarubicin
العودة إلى المحتوياتBefore you start this treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet from inside your pack of capsules. These will give you more information about idarubicin and will provide a full list of side-effects which you may experience from taking it.
Idarubicin will be given to you by a specialist doctor who is experienced in treating your condition. Your doctor will calculate what dose is right for you and will tell you how many capsules to take each day - it is important that you take idarubicin exactly as you are told to. Your dose will also be printed on the label of your pack. If you are unsure about what to do, or if you have any other concerns, you should contact your doctor or hospital clinic for advice.
Swallow the capsules whole with a drink of water. Do not open or chew the capsules. Try to take idarubicin at the same time each day, as this will help you to remember to take your doses. You can take the capsules before food, or after a light meal if preferred.
Your doctor will tell you how long your course of treatment will last. For some people this can just be a single dose; for others it can be a three-day course of treatment. You may or may not be asked to repeat the course of treatment after a few weeks.
If you are sick shortly after taking a dose, or if you forget a dose, contact your doctor or clinic for advice on what to do. You will be told whether to take the dose again, or wait until the next dose is due.
تحقيق أقصى استفادة من علاجك
العودة إلى المحتوياتYou must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests and check-ups during treatment.
Idarubicin lowers the number of white cells in your blood, increasing the chance of you getting an infection. You should take certain precautions to reduce the risk of infection - if possible, avoid people with infections and let your doctor know if you think you are getting a sore throat or if you have a high temperature.
Idarubicin may colour your urine red. There is no need to be concerned about this as it will go after a day or so. A few people taking idarubicin have noticed that their skin and nails have become discoloured too, although this occurs less often than the colour change to urine.
It is important that you do not get pregnant or father a child while you are taking idarubicin. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. To prevent pregnancy, women should use effective contraception for at least six months after finishing treatment. Men should continue to use contraception for three months after finishing treatment.
While you are taking idarubicin and for a while after you stop treatment, do not have any immunisations (vaccinations) without talking to your doctor first. Idarubicin lowers your body's resistance so there is a chance that you may get an infection from some vaccines.
إذا كنت ستخضع لعملية جراحية أو علاج أسنان، أخبر الشخص الذي يقوم بالعلاج بالأدوية التي تتناولها.
تابع القراءة أدناه
Can idarubicin cause problems?
العودة إلى المحتوياتAlong with their useful effects, most medicines can cause side-effects although not everyone experiences them. Before you start treatment with idarubicin, your doctor will discuss with you the possibility of unwanted side-effects occurring. The table below contains some of the most common ones. You will find a full list of side-effects in the manufacturer's information leaflet supplied with your capsules.
Very common idarubicin side-effects (these affect more than 1 in 10 people) | ماذا يمكنني أن أفعل إذا واجهت هذا؟ |
إسهال | Drink plenty of water to replace lost fluids. If this continues, speak with your doctor |
الشعور بالغثيان (الغثيان) أو التقيؤ (القيء) | Stick to simple foods. Let your doctor know about this, as an anti-sickness medicine may help |
Sore mouth or mouth ulcers | Brushing your teeth 2-3 times a day with a soft toothbrush and regularly using a mouth rinse may help to prevent this. If mouth ulcers become a problem, speak with your doctor |
A high temperature (fever), or symptoms of an infection | Let your doctor know about this straightaway |
Headache, tummy (abdominal) pain, chills, hair loss, lack of appetite, rash | Speak with your doctor or clinic for advice |
Other common side-effects include anaemia, bleeding, heart problems, and reduced numbers of blood cells | سيقوم طبيبك بفحص هذه الأمور |
If you experience any other symptoms which you think may be due to the capsules, speak with your doctor or pharmacist.
How to store idarubicin
العودة إلى المحتوياتاحفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.
احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.
Return any unused or unwanted capsules to your clinic or pharmacy to destroy. They will need special disposal.
معلومات هامة عن جميع الأدوية
العودة إلى المحتوياتمعلومات هامة عن جميع الأدوية
لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، اذهب إلى قسم الحوادث والطوارئ في مستشفى منطقتك. خذ العبوة معك، حتى لو كانت فارغة.
هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.
لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.
إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.
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غير متأكد من خلط الأدوية؟
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الأسئلة الشائعة
What type of cancers does idarubicin treat?
Idarubicin is primarily used to treat leukaemia, which is a type of cancer affecting white blood cells. It can also be prescribed for breast cancer if other treatments have not been effective.
How does idarubicin work to fight cancer?
Idarubicin is a chemotherapy medicine that works by stopping cancer cells from growing and dividing too quickly. This helps to reduce the number of these abnormal cells in your body.
Is it possible to receive idarubicin as an injection instead of capsules?
Yes, idarubicin is usually given as an injection. However, it can also be taken by mouth in the form of capsules. This particular article focuses on the capsule form of the medicine.
What should I do if I notice my urine turning red while taking idarubicin?
If you notice your urine is red, there is usually no need to be concerned. This is a known effect of idarubicin and the colour change should disappear after a day or so.
Can idarubicin affect my skin and nails?
While less common than the urine colour change, some people taking idarubicin have reported discolouration of their skin and nails. You should speak with your doctor or clinic for advice if you notice this.
Are there any specific precautions I should take to avoid infection while on idarubicin?
Yes, idarubicin can lower your white blood cell count, making you more susceptible to infections. You should try to avoid people who have infections. It's important to let your doctor know immediately if you think you are developing a sore throat or have a high temperature, as these can be signs of infection.
How should I dispose of any idarubicin capsules I no longer need?
You should never keep out-of-date or unwanted idarubicin capsules. Always return them to your hospital clinic or a pharmacy for proper disposal, as they require special handling.
قراءة إضافية ومراجع
- Manufacturer's PIL, Zavedos® Capsules 5 mg and 10 mg; Pfizer Limited, The electronic Medicines Compendium. Dated November 2021.
- الأدوية كاملة BNF الطبعة 89; الجمعية الطبية البريطانية والجمعية الملكية الصيدلانية لبريطانيا العظمى، لندن.
تابع القراءة أدناه
About the authorView full bio

مايكل ستيوارت، MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

سيد داجاني
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
تاريخ المقال
تمت كتابة المعلومات على هذه الصفحة ومراجعتها من قبل أطباء مؤهلين.
المراجعة التالية مستحقة: 18 يونيو 2026
19 يونيو 2023 | أحدث إصدار

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