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كبسولات إيداروبيسين

Zavedos

Swallow idarubicin capsules whole with a drink of water - do not bite, chew or suck the capsules.

Idarubicin may colour your urine red. This is nothing to worry about and will disappear after a day or two.

Keep your regular appointments with your doctor or hospital. You will need to have frequent blood tests and check-ups.

The most common side-effects are diarrhoea, feeling sick (nausea), sore mouth, and an increased risk of infection.

نظرة سريعة

  • Idarubicin is a chemotherapy medicine used to treat leukaemia and breast cancer.

  • It stops cancer cells from growing and dividing in the body.

  • You can take it as capsules or it can be given as an injection.

  • Do not get pregnant or father a child while taking idarubicin.

  • It can increase your risk of infection, so avoid people with infections.

  • Seek medical advice if you are sick after taking a dose or forget a dose.

  • Contact your doctor if you develop a high temperature or any signs of infection.

About idarubicin

نوع الدواء

An anthracycline chemotherapy medicine

يستخدم لـ

Treatment of leukaemia and breast cancer

يُعرف أيضًا باسم

Zavedos®

متوفر كـ

Capsules and injection

Idarubicin is used to treat some cancers. It is given in particular to treat اللوكيميا, which is cancer of white blood cells. It is also given for سرطان الثدي if other treatments have not proved effective. It can be used alone or alongside other medicines for the treatment of cancer.

In cancer, certain cells in the body grow and multiply too fast. أدوية العلاج الكيميائي (مضادة للسرطان) like idarubicin work by preventing the growth and division of cells, and this reduces the number of cancer cells your body makes. Idarubicin is usually given as an injection but it can also be taken by mouth in the form of capsules. This leaflet provides information about idarubicin capsules.

Before taking idarubicin

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking idarubicin it is important that your doctor or pharmacist knows:

  • إذا كنت حاملاً أو مرضعة.

  • إذا كان لديك أي مشاكل في طريقة عمل الكبد لديك، أو في طريقة عمل الكلى لديك.

  • If you have an infection or feel unwell.

  • If you have a heart condition, such as if you have had a heart attack in the past or if you have an unusual heartbeat.

  • إذا كنت تتناول أو تستخدم أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.

  • إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.

How to take idarubicin

  • Before you start this treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet from inside your pack of capsules. These will give you more information about idarubicin and will provide a full list of side-effects which you may experience from taking it.

  • Idarubicin will be given to you by a specialist doctor who is experienced in treating your condition. Your doctor will calculate what dose is right for you and will tell you how many capsules to take each day - it is important that you take idarubicin exactly as you are told to. Your dose will also be printed on the label of your pack. If you are unsure about what to do, or if you have any other concerns, you should contact your doctor or hospital clinic for advice.

  • Swallow the capsules whole with a drink of water. Do not open or chew the capsules. Try to take idarubicin at the same time each day, as this will help you to remember to take your doses. You can take the capsules before food, or after a light meal if preferred.

  • Your doctor will tell you how long your course of treatment will last. For some people this can just be a single dose; for others it can be a three-day course of treatment. You may or may not be asked to repeat the course of treatment after a few weeks.

  • If you are sick shortly after taking a dose, or if you forget a dose, contact your doctor or clinic for advice on what to do. You will be told whether to take the dose again, or wait until the next dose is due.

تحقيق أقصى استفادة من علاجك

  • You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests and check-ups during treatment.

  • Idarubicin lowers the number of white cells in your blood, increasing the chance of you getting an infection. You should take certain precautions to reduce the risk of infection - if possible, avoid people with infections and let your doctor know if you think you are getting a sore throat or if you have a high temperature.

  • Idarubicin may colour your urine red. There is no need to be concerned about this as it will go after a day or so. A few people taking idarubicin have noticed that their skin and nails have become discoloured too, although this occurs less often than the colour change to urine.

  • It is important that you do not get pregnant or father a child while you are taking idarubicin. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. To prevent pregnancy, women should use effective contraception for at least six months after finishing treatment. Men should continue to use contraception for three months after finishing treatment.

  • While you are taking idarubicin and for a while after you stop treatment, do not have any immunisations (vaccinations) without talking to your doctor first. Idarubicin lowers your body's resistance so there is a chance that you may get an infection from some vaccines.

  • إذا كنت ستخضع لعملية جراحية أو علاج أسنان، أخبر الشخص الذي يقوم بالعلاج بالأدوية التي تتناولها.

Can idarubicin cause problems?

Along with their useful effects, most medicines can cause side-effects although not everyone experiences them. Before you start treatment with idarubicin, your doctor will discuss with you the possibility of unwanted side-effects occurring. The table below contains some of the most common ones. You will find a full list of side-effects in the manufacturer's information leaflet supplied with your capsules.

Very common

idarubicin side-effects (these affect more than 1 in 10 people)

ماذا يمكنني أن أفعل إذا واجهت هذا؟

إسهال

Drink plenty of water to replace lost fluids. If this continues, speak with your doctor

الشعور بالغثيان (الغثيان) أو التقيؤ (القيء)

Stick to simple foods. Let your doctor know about this, as an anti-sickness medicine may help

Sore mouth or mouth ulcers

Brushing your teeth 2-3 times a day with a soft toothbrush and regularly using a mouth rinse may help to prevent this. If mouth ulcers become a problem, speak with your doctor

A high temperature (fever), or symptoms of an infection

Let your doctor know about this straightaway

Headache, tummy (abdominal) pain, chills, hair loss, lack of appetite, rash

Speak with your doctor or clinic for advice

Other common side-effects include anaemia, bleeding, heart problems, and reduced numbers of blood cells

سيقوم طبيبك بفحص هذه الأمور

If you experience any other symptoms which you think may be due to the capsules, speak with your doctor or pharmacist.

How to store idarubicin

  • احفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.

  • احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.

  • Return any unused or unwanted capsules to your clinic or pharmacy to destroy. They will need special disposal.

معلومات هامة عن جميع الأدوية

معلومات هامة عن جميع الأدوية

لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، اذهب إلى قسم الحوادث والطوارئ في مستشفى منطقتك. خذ العبوة معك، حتى لو كانت فارغة.

هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.

لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.

إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.

الإبلاغ عن الآثار الجانبية لدواء أو لقاح

إذا واجهت آثارًا جانبية، يمكنك الإبلاغ عنها عبر الإنترنت من خلال موقع بطاقة صفراء.

مدقق الأعراض

غير متأكد من خلط الأدوية؟

تحقق من التفاعلات المحتملة بين الأدوية والمكملات الغذائية والأطعمة قبل تناولها معًا.

الأسئلة الشائعة

If idarubicin can be given by injection or capsule, why does this leaflet only provide information about the capsules?

This particular leaflet focuses specifically on idarubicin capsules. While the medicine can be administered through injection, the information provided here is tailored to the oral capsule form of the treatment.

What is the typical duration for idarubicin treatment?

The duration of your idarubicin treatment will be determined by your doctor. For some individuals, it might be a single dose, while for others, it could be a three-day course. Your doctor may also decide if the treatment needs to be repeated after a few weeks.

What precautions should I take if idarubicin makes me more susceptible to infections?

Since idarubicin lowers your white blood cell count, increasing your risk of infection, you should try to avoid contact with people who have infections. It's also important to inform your doctor immediately if you notice symptoms like a sore throat or a high temperature.

How often will I need blood tests while on idarubicin?

You will need to have regular blood tests and check-ups during your treatment with idarubicin. This allows your doctor to monitor your progress and ensure the treatment is working effectively.

Why can't I have immunisations (vaccinations) while taking idarubicin?

You should not have immunisations (vaccinations) while taking idarubicin and for a period after treatment without first consulting your doctor. Idarubicin reduces your body's natural resistance, which means there's a risk you could develop an infection from some vaccines.

قراءة إضافية ومراجع

عن المؤلفعرض السيرة الذاتية الكاملة

صورة المؤلف

مايكل ستيوارت، MRPharmS

مدير مراجعة النشرات الطبية – متعاقد، صيدلي

بكالوريوس الصيدلة (مع مرتبة الشرف)، عضو الجمعية الملكية للصيادلة

مايكل هو صيدلي مجتمعي يمارس عمله في منطقة ميدلاندز وجنوب يوركشاير ولديه أكثر من 20 عامًا من الخبرة في تقديم المشورة بشأن الأدوية والحالات الطبية. لديه خلفية قوية في تدريب الرعاية الصحية، حيث قام بإنتاج وتقديم دورات تدريبية لفرق الصيدلة وموظفي دور الرعاية السكنية، بما في ذلك الممرضات. كما ساهم في مجالس استشارية للصيدلة لإدارة الحالات ذات الحدة المنخفضة في المجتمع.

حول المراجع

صورة المؤلف

سيد داجاني

تخرج سلطان دجاني من كلية الصيدلة في لندن عام 1994 وأصبح أصغر عضو منتخب في مجلس الجمعية الملكية للصيدلة منذ تأسيسها في عام 1842.

تاريخ المقال

تمت كتابة المعلومات على هذه الصفحة ومراجعتها من قبل أطباء مؤهلين.

  • المراجعة التالية مستحقة: 18 ديسمبر 2027
  • 19 يونيو 2023 | أحدث إصدار

    آخر تحديث بواسطة

    مايكل ستيوارت، MRPharmS

    مراجعة من قبل

    سيد داجاني
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