Olanzapine
Zalasta, Zyprexa
مراجعة من قبل Sid Dajaniآخر تحديث بواسطة Michael Stewart, MRPharmSLast updated 5 أغسطس 2024
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Olanzapine belongs to a group of medicines called antipsychotics. It is taken once daily.
حافظ على مواعيدك المنتظمة مع طبيبك. هذا لضمان متابعة تقدم حالتك.
The most common side-effects include feeling sleepy or dizzy, and increased weight.
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تابع القراءة أدناه
About olanzapine
نوع الدواء | An antipsychotic medicine |
يستخدم لـ | Easing the symptoms of schizophrenia and mania; preventing high mood swings in bipolar disorder |
يُعرف أيضًا باسم | Zalasta®; Zyprexa® |
متوفر كـ | Tablets, and melt-in-the-mouth (orodispersible) tablets |
Olanzapine belongs to a group of medicines called antipsychotics. It may have been prescribed for you to relieve the symptoms of الفصام, or alternatively, it may have been prescribed for the treatment and/or prevention of high mood swings (mania). In both of these conditions, olanzapine works on the balance of chemical substances in your brain.
Maintenance doses of olanzapine can also be given to people with schizophrenia by depot injection. There is a separate medicine leaflet providing more information about this, called Olanzapine long-acting injection.
Before taking olanzapine
العودة إلى المحتوياتSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking olanzapine it is important that your doctor knows:
إذا كنت حاملاً أو مرضعة.
إذا كنت تعاني من حالة قلبية أو مرض في الأوعية الدموية.
If you have liver, kidney, or prostate problems.
إذا كان لديك أي مشاكل في التنفس.
If you are very constipated or think you may have a blockage in your bowel.
If you have any of the following: epilepsy, diabetes (diabetes mellitus), depression, Parkinson's disease, raised pressure in your eye (glaucoma) or a condition which causes muscle weakness, called myasthenia gravis.
If you have ever had yellowing of your skin or of the whites of your eyes (jaundice).
If you have a blood or bone marrow disorder.
If you have a tumour on your adrenal gland (a condition called phaeochromocytoma).
If you have had an allergic reaction to a medicine.
إذا كنت تتناول أو تستخدم أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.
تابع القراءة أدناه
How to take olanzapine
العودة إلى المحتوياتBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about olanzapine and it will also provide you with a full list of the side-effects which you may experience from taking it.
Your dose will be adjusted to suit your condition, so take olanzapine tablets exactly as your doctor tells you to. It is usual to be prescribed one dose of olanzapine to take each day. Your dose will be printed on the label of your pack to remind you about what the doctor said to you.
You can take olanzapine tablets either before or after meals.
Try to get into the habit of taking your dose at the same time of day each day, as this will help you to remember to take it. If you do forget to take a dose, take it as soon as you remember. If you do not remember until the following day then skip the missed dose but remember to take the dose that is due on that day. Do not take two doses at the same time to make up for a forgotten dose.
If you have been given orodispersible tablets (e.g Zyprexa® Velotabs) - these are tablets which dissolve in your mouth - place the tablet on your tongue and allow it to dissolve. Alternatively, if you prefer, you can take the orodispersible tablet stirred into a small glassful of any of the following drinks: water, orange or apple juice, milk or coffee.
تحقيق أقصى استفادة من علاجك
العودة إلى المحتوياتYour treatment will require careful monitoring to make sure that you get the best possible benefit from olanzapine. Keep your regular doctor's appointments so that your progress can be checked. You will need to have some tests from time to time.
Treatment with olanzapine is usually long-term unless you experience an adverse effect. Keep taking it unless your doctor tells you otherwise. Stopping olanzapine suddenly can cause problems, so your doctor may want you to reduce your dose gradually if this becomes necessary.
If you drink alcohol, ask your doctor for advice. Alcohol increases the risk of side-effects from olanzapine so it is best avoided.
If you have diabetes you may need to check your blood glucose more frequently, as olanzapine may affect the levels of sugar in your blood. Your doctor will advise you about this.
Some medicines similar to olanzapine can cause the skin to become more sensitive to sunlight than normal. It may be advisable to use a sunscreen in bright sunlight until you know how your skin reacts.
Smoking may affect the amount of olanzapine in your body. Let your doctor know if you either start or stop smoking while you are taking olanzapine.
A small number of people taking medicines for mood disorders can have thoughts about harming themselves or ending their lives, particularly when a new medicine is started. It is very important that you tell your doctor about this if it happens to you.
If you are due to have any medical or dental treatment, tell the person carrying out the treatment which medicines you are taking. This is important because olanzapine may interfere with any anaesthetic you receive.
If you buy or take any 'over-the-counter' medicines or herbal remedies, please check with a pharmacist that they are suitable for you to take with olanzapine.
تابع القراءة أدناه
Can olanzapine cause problems?
العودة إلى المحتوياتAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with olanzapine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common olanzapine side-effects (these affect more than 1 in 10 people) | ماذا يمكنني أن أفعل إذا واجهت هذا؟ |
Feeling sleepy or dizzy | لا تقم بالقيادة ولا تستخدم الأدوات أو الآلات |
زيادة الوزن | Eat a well-balanced diet. Speak with a pharmacist if your weight becomes troublesome |
Changes to some blood test results | Your doctor will monitor for these |
Common olanzapine side-effects (these affect fewer than 1 in 10 people) | ماذا يمكنني أن أفعل إذا واجهت هذا؟ |
Feeling restless or tired | Speak with your doctor about this. Do not drive and do not use tools or machines while affected |
الإمساك | Drink plenty of water and eat a well-balanced diet |
جفاف الفم | حاول مضغ العلكة الخالية من السكر أو مص الحلويات الخالية من السكر |
Unusual or uncontrollable muscle movements | Speak with your doctor about these |
Increased appetite, feeling hot, swollen hands or feet, skin rash, reduced interest in sex, erectile dysfunction, aches and pains | ناقش هذه الأمور مع طبيبك إذا أصبحت أي منها مزعجة |
مهم: if you experience symptoms such as muscle stiffness, a very high temperature (fever), feeling confused, a fast heartbeat and sweating, you should contact your doctor immediately. These can be signs of a rare but serious condition known as neuroleptic malignant syndrome.
إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الأقراص، يرجى التحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.
How to store olanzapine
العودة إلى المحتوياتاحفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.
احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.
معلومات هامة عن جميع الأدوية
العودة إلى المحتوياتمعلومات هامة عن جميع الأدوية
لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، اذهب إلى قسم الحوادث والطوارئ في مستشفى منطقتك. خذ العبوة معك، حتى لو كانت فارغة.
هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.
لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.
إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.
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قراءة إضافية ومراجع
- Manufacturer's PIL, Zyprexa 2.5 mg, 5 mg, 7.5 mg, 10 mg, 15 mg, 20 mg film-coated tablets; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated December 2023.
- Manufacturer's PIL, Zyprexa Velotab® 5 mg, 10 mg, 15 mg and 20 mg orodispersible Tablets; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated December 2023.
- الأدوية كاملة BNF الطبعة 89; الجمعية الطبية البريطانية والجمعية الملكية الصيدلانية لبريطانيا العظمى، لندن.
تابع القراءة أدناه
About the authorView full bio

مايكل ستيوارت، MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

سيد داجاني
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
تاريخ المقال
تمت كتابة المعلومات على هذه الصفحة ومراجعتها من قبل أطباء مؤهلين.
المراجعة التالية مستحقة: 1 أغسطس 2027
5 أغسطس 2024 | أحدث إصدار

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