Rivastigmine
Alzest, Exelon, Prometax
مراجعة من قبل Sid Dajaniآخر تحديث بواسطة Michael Stewart, MRPharmSLast updated 29 Dec 2022
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Rivastigmine helps ease the symptoms of memory loss and dementia.
You will be given a small dose when you first start treatment. This will gradually be increased.
If you are taking the capsules or liquid medicine, take your doses after a meal.
If you are using the patches, make sure you remove the old patch before applying a new one.
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تابع القراءة أدناه
About rivastigmine
نوع الدواء | Anti-dementia medicine (an acetylcholinesterase inhibitor) |
يستخدم لـ | Dementia associated with Alzheimer's disease or Parkinson's disease |
يُعرف أيضًا باسم | Almuriva®; Alzest®; Erastig®; Exelon®; Nimvastid®; Prometax® |
متوفر كـ | Capsules, oral liquid medicine and skin patches |
Rivastigmine is used to treat the symptoms of dementia, such as memory loss. It is prescribed for people who have dementia which is associated with Alzheimer's disease or مرض باركنسون.
Rivastigmine cannot cure dementia, but it can slow down the progression of the symptoms in some people. It works by increasing the level of a natural chemical called acetylcholine. This is a chemical which allows nerve cells in the brain to communicate with each other, and it is known that people with dementia have low levels of it. The symptoms of dementia can be improved by increasing the levels of acetylcholine.
Rivastigmine will be prescribed by a specialist doctor. If you are a caregiver, please read this leaflet on behalf of the person who is receiving rivastigmine.
Before taking rivastigmine
العودة إلى المحتوياتSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking rivastigmine it is important that your doctor or pharmacist knows:
إذا كنت تعاني من مشاكل في الكبد أو الكلى.
إذا كنت تعاني من حالة قلبية.
If you have any problems with your breathing, such as asthma or chronic obstructive pulmonary disease (COPD).
If you have any problems passing urine.
If you have ever had a stomach (gastric) or duodenal ulcer.
If you have ever had fits (convulsions or seizures).
إذا كنت تتناول أو تستخدم أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.
إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.
تابع القراءة أدناه
How to take rivastigmine
العودة إلى المحتوياتBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about rivastigmine and a full list of side-effects which you may experience from it.
Your caregiver will help you take your medicine exactly as your doctor has told you. It is usual to be prescribed two doses to take each day. Your dose will be written on the label of your pack to remind you.
There are several different strengths of rivastigmine capsules and patches available, so make sure the product you have been given is the strength you were expecting. If you are unsure, ask your pharmacist for advice.
Ideally the capsules or liquid medicine should be taken with, or soon after, your breakfast and your evening meal. Try to take your doses at the same times each day as this will help you to remember to take them.
If you have been prescribed capsules to take, you should swallow the capsule whole without chewing or crushing it. Taking your doses with a small drink of water may help.
إذا نسيت تناول جرعة، فتناولها بمجرد أن تتذكر، إلا إذا كان الوقت قد اقترب لتناول الجرعة التالية، وفي هذه الحالة اترك الجرعة الفائتة. لا تتناول جرعتين معًا لتعويض الجرعة المنسية.
If you forget to take rivastigmine for several days, talk with your doctor before starting to take it again, as you may need to re-start your treatment on a lower dose.
If you have been prescribed skin patches, you will be asked to apply one patch each day. Make sure the previous day's patch is removed before you apply a new patch. If the patches cause any irritation to your skin, you should let your doctor know about this.
Taking rivastigmine oral liquid medicine
Read the manufacturer's instructions for the medicine you have been given.
Open the bottle and remove the oral dosing syringe and bottle adaptor provided.
Push the nozzle of the syringe into the bottle adaptor and insert it firmly into the top of the bottle.
Turn the bottle upside down.
Pull the plunger on the syringe a little way and push back up to get rid of any air bubbles. Then pull the plunger down to withdraw the required amount of medicine. Re-check your dose once you have removed the syringe from the bottle.
You can swallow the medicine straight from the syringe, or you can stir it into a glass of water to drink it.
When you have finished taking your dose, wipe the outside of the syringe with a tissue. The syringe can be cleaned in warm, soapy water.
Applying rivastigmine (Exelon®) patches
Open a packet and remove the patch from inside.
Apply the patch to an area of non-hairy skin on your back, upper arm, or chest (but not to your breast area). Press down on the patch with the palm of your hand for around 30 seconds. This will make sure it sticks firmly in place.
After 24 hours, remove the patch and do not use the same area of skin to apply another patch to for at least 14 days.
Repeat this process each day, removing the previous day's patch before applying a new patch.
If you forget to apply a new patch for more than three days, talk with your doctor before applying another patch, as you may need a lower dose.
تحقيق أقصى استفادة من علاجك
العودة إلى المحتوياتWhen starting your treatment your doctor will give you a small dose and then gradually increase the dose. This allows your doctor to make sure that you have the dose that helps your condition and avoids any unwanted side-effects.
Your doctor will want to check your progress every few weeks to make sure the dose is right for you and that you are getting benefit from this treatment. Try to keep these regular doctor's appointments.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking rivastigmine. This is because rivastigmine may affect the amount of any anaesthetic you may need.
If you buy any medicines, always check with a pharmacist that they are safe to take with your other medicines. Some medicines can interfere with the way rivastigmine works.
تابع القراءة أدناه
Can rivastigmine cause problems?
العودة إلى المحتوياتAlong with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. The table below lists some of the most common ones associated with rivastigmine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve over the first few days of taking a new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
Common rivastigmine side-effects | ماذا يمكنني أن أفعل إذا واجهت هذا؟ |
الشعور بالغثيان (الغثيان) أو التقيؤ (القيء)، عسر الهضم، ألم البطن (ألم البطن) | Let your doctor know if this happens, as your treatment may need reviewing |
إسهال | Drink plenty of water to replace any lost fluids. Let your doctor know if it continues |
الشعور بالدوار أو التعب | Be especially careful if you are using any tools or machines |
صداع | اشرب الكثير من الماء واطلب من الصيدلي أن يوصي بمسكن مناسب للألم. إذا استمرت الصداع، تحدث مع طبيبك |
Loss of appetite, losing weight, feeling anxious or agitated, trembling, falling, sweating, and skin reactions (with the patches) | إذا أصبحت أي من هذه الأمور مزعجة، تحدث مع طبيبك |
إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب هذا الدواء، تحدث مع طبيبك أو الصيدلي.
How to store rivastigmine
العودة إلى المحتوياتاحفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.
احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.
Once opened, a bottle of the medicine only keeps for one month. Do not store it or use it after this time.
معلومات هامة عن جميع الأدوية
العودة إلى المحتوياتمعلومات هامة عن جميع الأدوية
لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، اذهب إلى قسم الحوادث والطوارئ في مستشفى منطقتك. خذ العبوة معك، حتى لو كانت فارغة.
هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.
لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.
إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.
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غير متأكد من خلط الأدوية؟
تحقق من التفاعلات المحتملة بين الأدوية والمكملات الغذائية والأطعمة قبل تناولها معًا.
قراءة إضافية ومراجع
- Manufacturer's PIL, Rivastigmine Mylan 1.5 mg, 3 mg, 4.5 mg, 6 mg Hard Capsules; Mylan, The electronic Medicines Compendium. Dated April 2021.
- Manufacturer's PIL, Rivastigmine Rosemont 2 mg/ml Oral Solution; Rosemont Pharmaceuticals Ltd, The electronic Medicines Compendium. Dated September 2019.
- Manufacturer's PIL, Exelon® 4.6 mg/24h, 9.5 mg/24h, 13.3 mg/24h Transdermal Patch; Novartis Pharmaceuticals UK Ltd, The electronic Medicines Compendium. Dated November 2020.
- الأدوية كاملة BNF الطبعة 89; الجمعية الطبية البريطانية والجمعية الملكية الصيدلانية لبريطانيا العظمى، لندن.
تابع القراءة أدناه
About the authorView full bio

مايكل ستيوارت، MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

سيد داجاني
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
تاريخ المقال
تمت كتابة المعلومات على هذه الصفحة ومراجعتها من قبل أطباء مؤهلين.
Next review due: 28 Jun 2027
29 Dec 2022 | أحدث إصدار

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