توريميفين لعلاج سرطان الثدي
Fareston
مراجعة من قبل Sid Dajaniآخر تحديث بواسطة Michael Stewart, MRPharmSLast updated 27 Nov 2023
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Take one tablet of toremifene each day.
You can take the tablet before or after food.
The most common side-effects are hot flushes and sweating.
At a glance
Toremifene is a hormone treatment for metastatic breast cancer in women.
It works by blocking oestrogen receptors on cancer cells, preventing growth.
Do not take toremifene if you are still having menstrual periods.
Take one tablet daily at the same time each day, with or without food.
Common side effects include hot flushes, nausea, dizziness, and vaginal bleeding.
Seek medical advice if you experience pain or swelling in a leg, or shortness of breath.
في هذه المقالة:
Video picks for علاج السرطان والأدوية
تابع القراءة أدناه
About toremifene
نوع الدواء | An anti-oestrogen hormone antagonist |
يستخدم لـ | Metastatic breast cancer |
يُعرف أيضًا باسم | Fareston® |
متوفر كـ | أقراص |
Treatment options for women with سرطان الثدي include surgery, radiotherapy, chemotherapy and hormone treatment. Often a combination of two or more of these treatments is used. Toremifene is a hormone treatment.
Some breast cancers need the female hormone oestrogen to grow. The cells of these cancers have receptors on their surface that oestrogen can attach to and are called 'hormone receptor-positive' cancers. Toremifene works by blocking the receptors and this prevents oestrogen from reaching the cancer cells. This helps to control the cancer. It is prescribed for women with breast cancer where the cancer cells have also spread to another part of the body, such as the lungs, liver or bones. This sort of breast cancer is referred to as metastatic breast cancer, or secondary breast cancer.
Before taking toremifene
العودة إلى المحتوياتSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking toremifene it is important that your doctor knows:
If you are still having menstrual periods. If so, you should not take toremifene.
If you have had a stroke, a blood clot in your lungs, or deep venous thrombosis (DVT).
If you have a heart condition, or a heart rate or rhythm problem.
If you have been told the lining of your womb has become thickened, a condition called endometrial hyperplasia.
إذا كنت تواجه مشاكل في طريقة عمل الكبد لديك.
إذا كنت تعاني من اضطراب دم وراثي نادر يسمى البورفيريا.
إذا كنت تتناول أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.
إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.
تابع القراءة أدناه
How to take toremifene
العودة إلى المحتوياتBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about toremifene and will provide you with a full list of the side-effects which you may experience from taking it.
Take one 60 mg tablet each day, exactly as your doctor tells you to.
You may take toremifene at whatever time of day you find easiest to remember, but try to take your doses at the same time of day, each day. This will help you to remember to take your doses regularly.
You can take toremifene tablets before or after meals.
If you forget to take a dose at your usual time, take it as soon as you remember. If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.
تحقيق أقصى استفادة من علاجك
العودة إلى المحتوياتTry to keep your regular appointments with your doctor or clinic. This is so your doctor can check on your progress. This is particularly important if you also have bone cancer, as you will need to have regular blood tests when you start this treatment.
If you are having an operation, tell the person carrying out the treatment that you are taking toremifene.
If you buy any medicines, always check with a pharmacist that they are suitable to take with your other medicines.
تابع القراءة أدناه
Can toremifene cause problems?
العودة إلى المحتوياتAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with toremifene. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common toremifene side-effects (these affect more than 1 in 10 women) | ماذا يمكنني أن أفعل إذا واجهت هذا؟ |
Hot flushes and sweating | حاول الحفاظ على البرودة بارتداء ملابس خفيفة وفضفاضة |
Common toremifene side-effects (these affect fewer than 1 in 10 women) | ماذا يمكنني أن أفعل إذا واجهت هذا؟ |
الشعور بالغثيان (الغثيان) أو التقيؤ (القيء) | Stick to simple meals and avoid rich or spicy foods |
الشعور بالدوار أو التعب | لا تقم بالقيادة ولا تستخدم الأدوات أو الآلات أثناء التأثر |
Vaginal bleeding or discharge | Let your doctor know straightaway so the cause can be investigated. Your doctor will want to check to see if there are any changes that could cause concern in the lining of your womb |
Itchy skin rash, swollen feet or ankles, feeling depressed | إذا أصبحت أي من هذه الأمور مزعجة، تحدث مع طبيبك للحصول على نصيحة |
مهم: Some women taking toremifene have experienced a problem with a blood clot in the legs or lungs. Although this occurs less commonly than the side-effects mentioned above, if you experience any pain or swelling in a leg, or have any shortness of breath, please contact a doctor for advice as soon as possible.
إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الأقراص، تحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.
How to store toremifene
العودة إلى المحتوياتاحفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.
احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.
معلومات هامة عن جميع الأدوية
العودة إلى المحتوياتمعلومات هامة عن جميع الأدوية
لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، اذهب إلى قسم الحوادث والطوارئ في مستشفى منطقتك. خذ العبوة معك، حتى لو كانت فارغة.
هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.
لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.
إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.
MHRA - الإبلاغ عن التفاعلات الضارة
أبلغ عن الآثار الجانبية المشتبه بها للأدوية واللقاحات والسجائر الإلكترونية وحوادث الأجهزة الطبية والمنتجات المعيبة أو المزيفة (المزورة) إلى وكالة تنظيم الأدوية ومنتجات الرعاية الصحية لضمان الاستخدام الآمن والفعال.

غير متأكد من خلط الأدوية؟
تحقق من التفاعلات المحتملة بين الأدوية والمكملات الغذائية والأطعمة قبل تناولها معًا.
الأسئلة الشائعة
How does toremifene specifically target breast cancer growth?
Toremifene works by blocking the receptors on breast cancer cells that the female hormone oestrogen usually attaches to. This prevents oestrogen from stimulating the cancer cells, which helps to control the growth of cancers that need oestrogen to grow.
Can toremifene be used for all types of breast cancer?
No, toremifene is specifically prescribed for women with breast cancer where the cancer cells are 'hormone receptor-positive', meaning they need oestrogen to grow. It is also used when the cancer has spread to other parts of the body, such as the lungs, liver, or bones.
What should I do if I am still having menstrual periods?
If you are still experiencing menstrual periods, you should not take toremifene. It is important to inform your doctor about your menstrual status before starting this treatment.
Is it safe to take toremifene if I have a history of blood clots?
If you have a history of blood clots, such as a stroke, a blood clot in your lungs, or deep venous thrombosis (DVT), it is important that your doctor is aware of this before you start taking toremifene.
What should I do if I experience vaginal bleeding or discharge while taking toremifene?
If you experience vaginal bleeding or discharge, you should let your doctor know straight away. Your doctor will need to investigate the cause and check for any changes in the lining of your womb that could be a concern.
What are the common side effects I might experience?
Very common side effects (affecting more than 1 in 10 women) include hot flushes and sweating. Common side effects (affecting fewer than 1 in 10 women) can include feeling sick or being sick, feeling dizzy or tired, vaginal bleeding or discharge, itchy skin rash, swollen feet or ankles, and feeling depressed.
Are there any serious side effects I should be aware of?
Yes, although less common than other side effects, some women taking toremifene have experienced a blood clot in the legs or lungs. If you notice any pain or swelling in a leg, or have shortness of breath, you should contact a doctor for advice as soon as possible.
قراءة إضافية ومراجع
- Manufacturer's PIL, Fareston® 60 mg Tablets; Orion Pharma (UK) Limited, The electronic Medicines Compendium. Dated January 2021.
- الأدوية كاملة BNF الطبعة 89; الجمعية الطبية البريطانية والجمعية الملكية الصيدلانية لبريطانيا العظمى، لندن.
تابع القراءة أدناه
About the authorView full bio

مايكل ستيوارت، MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

سيد داجاني
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
تاريخ المقال
تمت كتابة المعلومات على هذه الصفحة ومراجعتها من قبل أطباء مؤهلين.
Next review due: 26 Nov 2026
27 Nov 2023 | أحدث إصدار

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