Carbamazepine for epilepsy

About carbamazepine

If you have epilepsy, it means that you have had more than one unexplained fit, or seizure. A seizure is a short episode of symptoms caused by a burst of abnormal electrical activity in your brain. Different parts of the brain control different functions of your body, so the symptoms that occur during a seizure will depend on where the abnormal burst of electrical activity occurs. Symptoms that may occur during a seizure can affect your muscles, sensations, behaviour, emotions, and consciousness, or a combination of these. The seizures can be prevented in most people by suitable antiepileptic medication. Carbamazepine is a commonly used medicine. It works by stabilising the electrical activity of your brain, which prevents the seizures from occurring.

Carbamazepine is also prescribed as a treatment for severe burning or stabbing pains in the face (called trigeminal neuralgia), and occasionally as part of the treatment for bipolar disorder (sometimes called manic depression). This is because it can modify some types of pain, and control some mood disorders. If you have been given carbamazepine for these (or any other reasons), ask your doctor if you have questions about your treatment.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking carbamazepine it is important that your doctor knows:

• إذا كنتِ حاملاً، تحاولين الإنجاب أو تقومين بالرضاعة الطبيعية.

• إذا كان لديك أي مشاكل في طريقة عمل الكلى لديك، أو في طريقة عمل الكبد لديك.

• If you have any heart condition.

• If you have increased pressure in your eyes, a condition known as glaucoma.

• If you have ever had any problems affecting your bone marrow.

• إذا كنت تعاني من اضطراب دم وراثي نادر يسمى البورفيريا.

• إذا كنت تتناول أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.

• إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about carbamazepine and will provide you with a full list of the side-effects which you may experience from taking it.

• Take carbamazepine exactly as your doctor tells you to. It is usual to start treatment on a low dose, and then for the dose to be increased gradually to a regular maintenance dose. If you are taking it for epilepsy, it is likely you will be asked to take one or two doses every day. Doses for children are tailored to their age and weight. If you have been prescribed it for another reason, you could be asked to take a dose three, or even four, times a day. Your dose will be printed on the label of the pack to remind you about what the doctor said to you.

• Try to take your doses of carbamazepine at the same times each day. Having a routine will help you to remember to take your doses regularly. Swallow the tablet with a drink of water. You can take most preparations of carbamazepine either before or after meals. If, however, you have been supplied with chewable tablets, you should take these during a mealtime.

• If you have been given carbamazepine prolonged-release tablets you must swallow the tablet whole - do not chew or crush the tablet.

• If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a forgotten dose.

• عند البدء في علاج جديد للصرع، قد يحدث تغيير في عدد أو نوع النوبات التي تعاني منها. سيقوم طبيبك بإرشادك حول هذا الأمر.

• Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You may need to have blood tests from time to time.

• Different formulations and brands of carbamazepine can act in a slightly different way in your body. Because of this, it is important that you continue to take tablets from the same manufacturer as you have had before. So, each time you collect a prescription, check to make sure your supply looks the same and that the brand name is the same. If you are unsure, or if you have any questions about your prescription, please ask your pharmacist to check it for you.

• If you buy any medicines, check with a pharmacist that they are suitable for you to take. This is because some medicines interfere with carbamazepine, and carbamazepine can also alter the way other medicines work.

• Ask your doctor for advice before drinking alcohol while you are on carbamazepine. Your doctor may recommend you do not drink alcohol because it increases the risk of side-effects.

• يجب على الأشخاص المصابين بالصرع التوقف عن القيادة في البداية. سيقوم طبيبك بإرشادك حول متى يمكن أن يكون من الممكن لك البدء في القيادة مرة أخرى. عادةً ما يكون ذلك بعد مرور عام خالٍ من النوبات.

• Carbamazepine may harm an unborn child so you must avoid getting pregnant. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. If you want to have a family, discuss this with your doctor so that you can be given advice from a specialist قبل you become pregnant.

• أثناء تلقيك العلاج من الصرع، هناك خطر صغير بأن تتطور لديك تغييرات في المزاج، أفكار مزعجة ومشاعر حول الانتحار. إذا حدث ذلك، يجب عليك إبلاغ طبيبك على الفور.

• You need to take carbamazepine regularly every day. Do not stop taking it unless your doctor tells you to stop. Stopping treatment suddenly can cause problems and your doctor will want you to reduce your dose gradually if this becomes necessary.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with carbamazepine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Many of the side-effects can occur when first starting carbamazepine, but should settle down as your body adjusts to the new medicine. Speak with your doctor if they continue or become troublesome.

إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الدواء، تحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.

• احفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.

• احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.