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Moexipril - an ACE inhibitor

Clinical author's note 27/11/2017: مايكل ستيوارت: Moexipril was discontinued in the UK in March 2016. At the time of review there are no branded or generic products containing moexipril available in the UK. Moexipril may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

The first dose of moexipril may make you feel dizzy, so it is best taken just before bedtime.

Some painkillers and indigestion remedies interfere with moexipril, so ask your pharmacist for advice before you buy any medicines.

Some people taking moexipril can develop a troublesome cough. If this happens to you, let your doctor know.

At a glance

  • Moexipril is an ACE inhibitor medicine prescribed to lower high blood pressure.

  • It works by widening blood vessels and reducing water reabsorbed by your kidneys.

  • Take your first dose at bedtime as you may feel dizzy.

  • Try to take it before food as this helps your body absorb more of the medicine.

  • Common side-effects include a dry cough, dizziness, and headache.

  • Do not use salt substitutes as they contain high levels of potassium.

  • Seek medical advice immediately if you have difficulty breathing, swelling of the face, or yellow skin or eyes.

تابع القراءة أدناه

About moexipril

نوع الدواء

مثبط إنزيم محول للأنجيوتنسين (ACE)

يستخدم لـ

ارتفاع ضغط الدم (فرط ضغط الدم)

يُعرف أيضًا باسم

Perdix® (discontinued); Univasc® (US)

متوفر كـ

أقراص

Moexipril belongs to a class of medicines called angiotensin-converting enzyme inhibitors, or ACE inhibitors. You will have been prescribed it to reduce ارتفاع ضغط الدم (فرط ضغط الدم). Although people with high blood pressure usually feel well, if left untreated, high blood pressure can harm the heart and damage blood vessels, leading to a heart attack or stroke.

ACE inhibitors like moexipril prevent your body from creating a hormone known as angiotensin II. They do this by blocking (inhibiting) a chemical called angiotensin-converting enzyme. This widens your blood vessels and helps to reduce the amount of water put back into your blood by your kidneys. These actions help to lower the high blood pressure.

You may be prescribed moexipril on its own, or alongside other medicines to help your condition.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking moexipril it is important that your doctor knows:

  • إذا كنتِ حاملاً، تحاولين الإنجاب أو تقومين بالرضاعة الطبيعية.

  • If you have problems with the way your kidneys work, or any problems with the way your liver works.

  • إذا كنت تعاني من نقص في السوائل في الجسم (الجفاف) - على سبيل المثال، إذا كنت قد أصبت بالإسهال أو المرض مؤخرًا.

  • إذا قيل لك أن لديك تراكمًا للترسبات الدهنية على جدران شرايينك، وهي حالة تُسمى تصلب الشرايين.

  • إذا كنت تعاني من نوع معين من ضعف الدورة الدموية يسمى مرض الشرايين المحيطية.

  • If you have collagen vascular disease - this includes conditions such as systemic lupus erythematosus (SLE) and scleroderma.

  • If you have been told you have a heart problem such as heart muscle disease (cardiomyopathy), or narrowing of the main blood vessel from your heart (aortic stenosis).

  • إذا كنت قد تعرضت في أي وقت مضى لرد فعل حيث يتورم وجهك أو لسانك أو حلقك (وذمة وعائية).

  • إذا كنت تتلقى علاجًا لإزالة التحسس للحماية من لسعات النحل والدبابير.

  • إذا كنت تتلقى علاج غسيل الكلى، أو علاج لإزالة الكوليسترول من دمك بواسطة جهاز (فصل الدهون منخفضة الكثافة).

  • إذا كنت تتناول أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.

  • If you have ever had an allergic or unusual reaction to any other ACE inhibitor (such as lisinopril, ramipril or perindopril), or to any other medicine.

تابع القراءة أدناه

  • Before you start this treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about moexipril and will provide you with a full list of side-effects which you may experience from taking it.

  • Take moexipril exactly as your doctor tells you to. You will be asked to take one dose each day.

  • Your doctor will advise you to take your very first dose at bedtime. This is because the first dose may make you feel dizzy.

  • After the first dose, you can generally take moexipril at any time of day you find easy to remember - for most people, this will be first thing in the morning. Try to take your dose at the same time each day. You should ideally take the tablet before food as this allows your body to absorb more of the medicine. Swallow the tablet with a drink of water.

  • If you forget to take a dose at your usual time, take it as soon as you remember. If you do not remember until the following day, skip the forgotten dose. Do not take two doses at the same time to make up for a missed dose.

  • Try to keep your regular appointments with your doctor. This is so your progress can be monitored. Your doctor may want you to have some blood tests from time to time to check that your kidneys are working well.

  • It is very important that you follow any dietary and lifestyle advice that you are given by your doctor. This may include advice about eating a healthy diet, not smoking, and taking regular exercise.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with moexipril. This is because some medicines (such as anti-inflammatory painkillers and indigestion remedies) may interfere with your treatment.

  • It is likely that your doctor will advise that you do not use salt substitutes while you are taking moexipril. These products have a high content of potassium which could be harmful for you.

  • If you have a bout of sickness or diarrhoea, your doctor may advise you to stop taking the tablets for a short while until you are drinking sufficient fluids again. This is to help prevent any damage to your kidneys while you are dehydrated.

  • If you drink alcohol, ask your doctor for advice about drinking alcohol while you are on moexipril. Alcoholic drinks may make you feel light-headed or dizzy, and may not be advisable for you.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking moexipril tablets. This is because some anaesthetics may cause your blood pressure to drop too far.

  • Treatment with moexipril is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise.

تابع القراءة أدناه

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with moexipril. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common moexipril side-effects (these affect fewer than 1 in 10 people)

ماذا يمكنني أن أفعل إذا واجهت هذا؟

سعال جاف ومزعج

If this continues, speak with your doctor as an alternative medicine may be better for you

Feeling dizzy, especially when standing up

Getting up more slowly should help. If you begin to feel dizzy, sit or lie down for a few moments before standing. If this continues beyond the first few days, speak with your doctor. Do not drive and do not use tools or machines while you feel dizzy

صداع

اشرب الكثير من الماء واطلب من الصيدلي أن يوصي بمسكن مناسب للألم. إذا استمرت الصداع، أخبر طبيبك

الشعور بالتعب

If this happens, do not drive and do not use tools or machines until you feel more awake

Flushing, rash

Speak with your doctor if either of these become troublesome

مهم: if you experience any of the following rare but serious symptoms, stop taking moexipril and contact your doctor for advice straightaway:

  • أي صعوبة في التنفس، أو تورم في وجهك، فمك، لسانك أو حلقك. هذه علامات على رد فعل تحسسي.

  • Any yellowing of your skin or of the whites of your eyes. These may be signs of jaundice, which is a rare side-effect.

  • A severe skin rash.

إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الأقراص، تحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.

  • احفظ جميع الأدوية بعيدًا عن متناول الأطفال وأنظارهم.

  • احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.

معلومات هامة عن جميع الأدوية

لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، اذهب إلى قسم الحوادث والطوارئ في مستشفى منطقتك. خذ العبوة معك، حتى لو كانت فارغة.

هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.

لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.

إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.

MHRA - الإبلاغ عن التفاعلات الضارة

أبلغ عن الآثار الجانبية المشتبه بها للأدوية واللقاحات والسجائر الإلكترونية وحوادث الأجهزة الطبية والمنتجات المعيبة أو المزيفة (المزورة) إلى وكالة تنظيم الأدوية ومنتجات الرعاية الصحية لضمان الاستخدام الآمن والفعال.

symptom checker

غير متأكد من خلط الأدوية؟

تحقق من التفاعلات المحتملة بين الأدوية والمكملات الغذائية والأطعمة قبل تناولها معًا.

الأسئلة الشائعة

Why is it important to treat high blood pressure, even if I feel well?

Even if you feel well, untreated high blood pressure can cause serious harm to your heart and damage your blood vessels over time. This damage can increase your risk of having a heart attack or a stroke.

How does moexipril actually work to lower my blood pressure?

Moexipril is an ACE inhibitor. It works by preventing your body from producing a hormone called angiotensin II. By blocking this hormone, your blood vessels widen, and your kidneys return less water to your blood. Both of these actions help to lower your high blood pressure.

Can I take moexipril if I have kidney problems?

If you have problems with your kidneys, or any liver problems, it is important to let your doctor know before you start taking moexipril. Your doctor will assess if it's suitable for you or if extra care is needed.

What should I do if I forget to take a dose of moexipril?

If you forget to take a dose at your usual time, take it as soon as you remember. However, if you don't remember until the next day, you should skip the missed dose completely. Do not take two doses at the same time to compensate for a forgotten one.

Are there any foods or drinks I should avoid while taking moexipril?

While taking moexipril, your doctor will likely advise you to avoid using salt substitutes, as they contain high levels of potassium which could be harmful. If you drink alcohol, you should ask your doctor for advice, as alcoholic drinks might make you feel light-headed or dizzy and may not be recommended for you.

Could moexipril affect other medicines I'm currently taking?

Yes, some medicines can interfere with moexipril. When you buy any medicines, including non-prescription, herbal, or complementary ones, always check with a pharmacist to ensure they are safe to take with moexipril. For example, some anti-inflammatory painkillers and indigestion remedies may interact with your treatment.

What should I do if I get a dry cough from moexipril?

A dry, irritating cough is a common side-effect of moexipril. If this cough continues and becomes troublesome, you should speak with your doctor. They may consider prescribing an alternative medicine that is better suited for you.

What are the signs of a serious allergic reaction to moexipril?

Although rare, you should stop taking moexipril immediately and contact your doctor straight away if you experience any difficulty breathing, or swelling of your face, mouth, tongue, or throat. These could be signs of a serious allergic reaction.

قراءة إضافية ومراجع

تابع القراءة أدناه

About the authorView full bio

Author image

مايكل ستيوارت، MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

سيد داجاني

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

تاريخ المقال

تمت كتابة المعلومات على هذه الصفحة ومراجعتها من قبل أطباء مؤهلين.

  • المراجعة التالية مستحقة: 10 ديسمبر 2026
  • 11 ديسمبر 2023 | أحدث إصدار

    آخر تحديث بواسطة

    مايكل ستيوارت، MRPharmS

    مراجعة من قبل

    سيد داجاني
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