تخطي إلى المحتوى الرئيسي

بوساكونازول لعلاج العدوى الفطرية

Noxafil

Posaconazole treats fungal infections within your body.

If you have been supplied with tablets, you can take your doses before or after meals. If you have been supplied with liquid medicine, try to take each dose with a snack or straight after a meal.

If you start being sick (vomiting) or develop diarrhoea, let your doctor know.

نظرة سريعة

  • Posaconazole is an antifungal medicine used to treat or prevent serious fungal infections.

  • يتوفر على شكل أقراص ودواء سائل فموي.

  • How you take posaconazole depends on whether you have tablets or liquid.

  • You must not get pregnant whilst taking posaconazole.

  • Common side-effects include feeling sick, diarrhoea, and tummy pain.

  • If you experience severe or troublesome side-effects, tell your doctor.

About posaconazole

نوع الدواء

مضاد للفطريات

يستخدم لـ

العدوى الفطرية

يُعرف أيضًا باسم

Noxafil®

متوفر كـ

الأقراص والأدوية السائلة الفموية

Fungal infections within the body sometimes occur. You are more at risk of developing an internal fungal infection if your immune system does not work properly. For example, if you are taking العلاج الكيميائي, or if your immune system is being suppressed following an organ or cell transplant. Internal fungal infections can be serious and, sometimes, life-threatening.

Posaconazole is used to treat (or prevent) serious fungal infections, particularly when other antifungal medicines have not been effective or are not suitable. It works by stopping the growth of the fungi causing the infection.

Before taking posaconazole

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking posaconazole it is important that your doctor knows:

  • إذا كنت حاملاً أو مرضعة.

  • إذا كنت تعاني من مشاكل في الكبد.

  • If you have any heart or heart rhythm problems.

  • إذا كنت تعاني من البورفيريا، وهو اضطراب دم وراثي نادر.

  • إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.

  • If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. This is because a number of medicines can interfere with the way posaconazole works.

How to take posaconazole

  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about posaconazole and will provide you with a full list of side-effects which you may experience from taking it.

  • Take posaconazole exactly as your doctor tells you to. How frequently you will need to take it will depend upon why you are taking it, but as a guide, it will range from once a day to four times daily if you are taking liquid medicine. If you are taking tablets, it is likely you will be prescribed 300 mg (three tablets) to take twice daily on the first day, and then 300 mg (three tablets) to take once a day on the following days.

  • The tablets can be taken either before or after meals. Swallow the tablets with a drink of water. Do not crush or break the tablets - they should be swallowed whole.

  • The liquid medicine should be taken during, or straight after, a meal or snack where possible as this will help your body to absorb the medicine. If you are unable to eat much, make sure your doctor knows this, as you may be better taking smaller doses more frequently. Use the spoon included in your pack to measure out your doses. It is marked for doses of 2.5 ml and 5 ml.

  • Space your doses evenly throughout the day, and keep taking this medicine until your course is finished unless you are told otherwise. This is to make sure there is no chance of further infection.

  • If you forget to take a dose, take it as soon as you remember. However, if when you remember, it is nearly time for your next dose, leave out the forgotten dose. Do not take two doses together to make up for a missed dose.

تحقيق أقصى استفادة من علاجك

  • Remember to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor will want to do some blood tests during this treatment, to check that your liver is working properly.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with posaconazole. This is because several medicines interfere with it and may either decrease how well it works or increase the risk you may experience side-effects.

  • You must not get pregnant while you are taking posaconazole. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner if this is relevant for you.

Can posaconazole cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with posaconazole. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common posaconazole side-effects (these affect around 1 in 10 people)


ماذا يمكنني أن أفعل إذا واجهت هذا؟

الشعور بالغثيان (الغثيان) أو التقيؤ (القيء)

If this is severe, let your doctor know straightaway

إسهال

Drink plenty of water to replace lost fluids. If it continues or is severe, let your doctor know straightaway

Tummy (abdominal) pain, indigestion, lack of appetite

Stick to simple foods - avoid spicy meals

Feeling sleepy or dizzy

Rest whenever you can. Do not use tools or machines, and do not drive

جفاف الفم

حاول مضغ العلكة الخالية من السكر أو مص الحلويات الخالية من السكر

Headache, itchy rash, tingling feelings, high temperature (fever), infection

إذا أصبح أي من هذه الأمور مزعجًا، أخبر طبيبك

Feeling confused or weak (due to abnormal levels of electrolytes in your blood)

Your doctor will be monitoring your blood for this

If you experience any other symptoms which you think may be due to the medicine, speak with your doctor or pharmacist.

How to store posaconazole

  • احفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.

  • احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.

  • The liquid medicine keeps for four weeks once the bottle has been opened. Do not use it after this time.

معلومات هامة عن جميع الأدوية

معلومات هامة عن جميع الأدوية

لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، توجه فورًا إلى قسم الحوادث والطوارئ في مستشفى منطقتك. خذ العبوة معك، حتى لو كانت فارغة.

هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.

لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.

إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.

الإبلاغ عن الآثار الجانبية لدواء أو لقاح

إذا واجهت آثارًا جانبية، يمكنك الإبلاغ عنها عبر الإنترنت من خلال موقع بطاقة صفراء.

مدقق الأعراض

غير متأكد من خلط الأدوية؟

تحقق من التفاعلات المحتملة بين الأدوية والمكملات الغذائية والأطعمة قبل تناولها معًا.

الأسئلة الشائعة

What happens if I forget to take a dose of liquid posaconazole and I'm unable to eat?

If you are taking the liquid medicine and miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the forgotten dose. Do not take two doses at once to compensate. If you are regularly unable to eat much, you should inform your doctor because they might advise an adjusted dosing schedule with smaller doses more frequently to ensure proper absorption.

Are there any specific activities I should avoid while taking posaconazole, especially if I experience side-effects?

Yes, if you experience side-effects such as feeling sleepy or dizzy, you should avoid driving, operating tools, or using machinery. It's important to rest whenever you can if these side-effects occur.

How will my doctor monitor my health while I'm taking posaconazole?

Your doctor will schedule regular appointments to check on your progress. They will also perform blood tests during your treatment to ensure your liver is functioning properly. Additionally, they will monitor your blood for abnormal levels of electrolytes, which can cause confusion or weakness.

What should I do if I think I've taken too much posaconazole?

If you suspect that you or someone else has taken more than the prescribed dose of posaconazole, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty.

Can I give my posaconazole to someone else if they have similar symptoms?

No, you should never give your medicine to other people, even if their condition seems to be the same as yours. This medicine is prescribed specifically for you.

How should I dispose of any leftover or expired liquid posaconazole?

Any out-of-date or unwanted medicines, including liquid posaconazole that has been open for more than four weeks, should not be kept. You should take them to your local pharmacy, which will dispose of them for you.

قراءة إضافية ومراجع

عن المؤلفعرض السيرة الذاتية الكاملة

صورة المؤلف

مايكل ستيوارت، MRPharmS

مدير مراجعة النشرات الطبية – متعاقد، صيدلي

بكالوريوس الصيدلة (مع مرتبة الشرف)، عضو الجمعية الملكية للصيادلة

مايكل هو صيدلي مجتمعي يمارس عمله في منطقة ميدلاندز وجنوب يوركشاير ولديه أكثر من 20 عامًا من الخبرة في تقديم المشورة بشأن الأدوية والحالات الطبية. لديه خلفية قوية في تدريب الرعاية الصحية، حيث قام بإنتاج وتقديم دورات تدريبية لفرق الصيدلة وموظفي دور الرعاية السكنية، بما في ذلك الممرضات. كما ساهم في مجالس استشارية للصيدلة لإدارة الحالات ذات الحدة المنخفضة في المجتمع.

حول المراجع

صورة المؤلف

سيد داجاني

تخرج سلطان دجاني من كلية الصيدلة في لندن عام 1994 وأصبح أصغر عضو منتخب في مجلس الجمعية الملكية للصيدلة منذ تأسيسها في عام 1842.

تاريخ المقال

تمت كتابة المعلومات على هذه الصفحة ومراجعتها من قبل أطباء مؤهلين.

  • المراجعة التالية مستحقة: 18 يوليو 2026
  • 19 يوليو 2023 | أحدث إصدار

    آخر تحديث بواسطة

    مايكل ستيوارت، MRPharmS

    مراجعة من قبل

    سيد داجاني
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