Prasugrel tablets
Efient
مراجعة من قبل Sid Dajaniآخر تحديث بواسطة Michael Stewart, MRPharmSLast updated 9 Jan 2023
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You will be given six 10 mg tablets to take as your first dose. After this, take one tablet daily.
The most common unwanted effect is an increased risk of bleeding. It is important that you let your doctor know if you notice any unusual or unexpected bleeding or bruising.
If you need to take any painkillers, check with your doctor or pharmacist that they are suitable for you. Some painkillers interact with prasugrel.
At a glance
Prasugrel is an antiplatelet medicine that helps stop blood clots forming.
It is taken after a procedure to open a blocked artery in the heart (PCI), often with a stent.
You will also take aspirin alongside prasugrel.
Tell your doctor if you are pregnant, breastfeeding, or have a bleeding condition.
You will take six tablets for the first dose, then one tablet daily.
Prasugrel can cause bleeding, bruising, or nosebleeds.
Tell your doctor or pharmacist if you experience any side-effects.
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تابع القراءة أدناه
About prasugrel tablets
نوع الدواء | An antiplatelet medicine |
يستخدم لـ | To prevent clots forming in blood vessels after a procedure called percutaneous coronary intervention (to open a blocked artery in the heart or for a stent insertion) |
يُعرف أيضًا باسم | Efient® |
متوفر كـ | أقراص |
In your blood there are 'sticky' cells called platelets. When you cut yourself, the platelets stick to each other (clot) to seal the wound. Sometimes platelets stick to each other inside an artery - this is called a thrombus. If a thrombus forms in a blood vessel around your heart, this reduces the flow of blood to your heart. The term acute coronary syndrome (ACS) covers a range of disorders that are caused by this underlying problem, and include النوبات القلبية and a type of chest pain known as unstable angina.
If you require a procedure to open a blocked artery in your heart because you have already had a heart attack or because you have unstable angina, you will be prescribed an antiplatelet medicine like prasugrel during the procedure.
For some people with ACS, the most appropriate treatment is to have a stent inserted into the blocked or narrowed artery to restore the flow of blood. A stent is like a wire mesh tube which gives support to the blood vessel. After a stent has been inserted, antiplatelet medicines are given routinely. These medicines reduce the stickiness of platelets, and this helps prevent the platelets from sticking to the inside of the artery and going on to form a further clot (thrombus).
Prasugrel is one of these antiplatelet medicines. Your doctor will also prescribe aspirin for you to take alongside prasugrel. Aspirin is another antiplatelet medicine.
Before taking prasugrel tablets
العودة إلى المحتوياتSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking prasugrel tablets it is important that your doctor knows:
إذا كنت حاملاً أو مرضعة.
إذا كان لديك أي مشاكل في طريقة عمل الكبد لديك، أو إذا كان لديك أي مشاكل في طريقة عمل الكلى لديك.
If you have ever had a stroke, or a transient ischaemic attack (sometimes called a TIA or 'mini-stroke').
If you have a condition which causes bleeding, such as a recent wound or a stomach ulcer.
If you have ever had an allergic reaction to a medicine, particularly if you have had a bad reaction to any other antiplatelet medicine (for example, clopidogrel).
إذا كنت تتناول أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.
تابع القراءة أدناه
How to take prasugrel tablets
العودة إلى المحتوياتBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about prasugrel, and it will also provide you with a full list of the side-effects which you could experience from taking it.
Take the tablets exactly as your doctor tells you to. On the first day of treatment, you will be given six 10 mg tablets (60 mg) to take so that you get sufficient medicine into your bloodstream to begin with. After this, you will be prescribed one tablet to take each day. For most people, the tablets will contain 10 mg prasugrel, although depending upon your body weight you could be prescribed the lower 5 mg strength tablet.
Swallow the tablets with a drink of water - do not crush or chew the tablets as you swallow. You can take prasugrel tablets either with or without food.
Try to take your doses around the same time of day, each day. This will help you to remember to take prasugrel regularly.
إذا نسيت تناول جرعة، فتناولها بمجرد أن تتذكر. إذا لم تتذكر حتى اليوم التالي، فاترك الجرعة المنسية من اليوم السابق وتناول الجرعة المستحقة كالمعتاد. لا تتناول جرعتين في نفس الوقت لتعويض الجرعة الفائتة.
تحقيق أقصى استفادة من علاجك
العودة إلى المحتوياتTry to keep all your regular appointments with your doctor. This is so your doctor can check on your progress. It is likely you will require a course of treatment with prasugrel which lasts for up to 12 months.
If you buy any medicines, check with a pharmacist that they are suitable for you to take with prasugrel tablets. Some medicines, called non-steroidal anti-inflammatory drugs (NSAIDs), can increase the risk of bleeding, so check with a pharmacist before you buy any painkillers. Also, do not take any preparations containing aspirin that have not been prescribed for you by your doctor. Several medicines for pain relief and cold relief that can be bought at retail outlets contain aspirin or ibuprofen - you should not take these, so check the label carefully before you buy.
If you are due to have an operation, before the treatment is due, tell the person carrying out the treatment that you are taking prasugrel. This is because any bleeding may take longer than normal to stop so your treatment may need to be interrupted for a short while before the operation. You should also let your dentist know that you are taking prasugrel before you receive any dental treatment.
تابع القراءة أدناه
Can prasugrel tablets cause problems?
العودة إلى المحتوياتAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with prasugrel. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common prasugrel side-effects (these affect fewer than 1 in 10 people) | ماذا يمكنني أن أفعل إذا واجهت هذا؟ |
Bleeding, bruising, nosebleeds. Stopping bleeding could take longer than normal | Let your doctor know if you notice any unusual or unexpected bleeding or bruising |
Skin rash, feeling tired (due to anaemia) | Let your doctor know, especially if it is severe or troublesome |
إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الأقراص، تحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.
How to store prasugrel tablets
العودة إلى المحتوياتاحفظ جميع الأدوية بعيدًا عن متناول ورؤية الأطفال.
احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.
معلومات هامة عن جميع الأدوية
العودة إلى المحتوياتمعلومات هامة عن جميع الأدوية
لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، اذهب إلى قسم الحوادث والطوارئ في مستشفى منطقتك. خذ العبوة معك، حتى لو كانت فارغة.
هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.
لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.
إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.
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الأسئلة الشائعة
What specifically is a percutaneous coronary intervention and why do I need prasugrel afterwards?
A percutaneous coronary intervention is a procedure to open a blocked artery in your heart. This could be to address a heart attack, unstable angina, or if a stent is inserted into a blocked or narrowed artery. You will be prescribed prasugrel afterwards because it is an antiplatelet medicine that reduces the stickiness of platelets, helping to prevent them from forming further clots on the inside of the artery or around the stent.
How long will I need to take prasugrel tablets?
It is likely you will need to continue treatment with prasugrel for a course that lasts up to 12 months. Your doctor will monitor your progress and advise you on the exact duration of your treatment.
What should I do if I accidentally take two doses of prasugrel?
If you suspect that you or someone else might have taken an overdose of this medicine, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty.
Are there any specific painkillers I should avoid while taking prasugrel?
Yes, you should avoid certain painkillers. Some medicines, known as non-steroidal anti-inflammatory drugs (NSAIDs), can increase your risk of bleeding when taken with prasugrel. You should also not take any preparations containing aspirin that haven't been prescribed by your doctor. Many over-the-counter pain relief and cold relief medicines contain either aspirin or ibuprofen, which are NSAIDs, so always check the label carefully or ask a pharmacist before buying any.
Why is it important to tell my dentist that I'm taking prasugrel?
It's important to inform your dentist that you are taking prasugrel before any dental treatment begins. This is because prasugrel can make any bleeding take longer than normal to stop. Your dentist will need to be aware of this to take appropriate precautions.
What should I do if I notice unusual bleeding or bruising while on prasugrel?
Prasugrel can cause bleeding, bruising, and nosebleeds, and stopping bleeding might take longer than usual. If you notice any unusual or unexpected bleeding or bruising that seems severe or troublesome, you should let your doctor know.
قراءة إضافية ومراجع
- الأدوية كاملة BNF الطبعة 89; الجمعية الطبية البريطانية والجمعية الملكية الصيدلانية لبريطانيا العظمى، لندن.
- Manufacturer's PIL, Prasugrel 10mg film-coated tablets; Accord Healthcare Ltd, The electronic Medicines Compendium. Dated January 2019.
تابع القراءة أدناه
About the authorView full bio

هيلين ألين، ماجستير في الصيدلة
Pharmacist, Medical Author
MPharm
Helen Allen qualified as a Pharmacist in 1979 and spent 3 years as the drug information leaflets' author for EMIS.
About the reviewer

سيد داجاني
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
تاريخ المقال
تمت كتابة المعلومات على هذه الصفحة ومراجعتها من قبل أطباء مؤهلين.
المراجعة التالية مستحقة: 8 يوليو 2027
9 Jan 2023 | أحدث إصدار
10 Sept 2013 | نُشر في الأصل
كتبه:
هيلين ألين، ماجستير في الصيدلة

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