Solifenacin
Vesicare
مراجعة من قبل Sid Dajaniآخر تحديث بواسطة Michael Stewart, MRPharmSLast updated 17 Aug 2024
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Take one tablet every day.
There are two strengths of tablet available - 5 mg and 10 mg. Your doctor will tell you which strength is right for you.
The most common side-effects are dry mouth and blurred vision.
At a glance
Solifenacin is a medicine for symptoms of urinary urgency, frequency, and incontinence.
It works by relaxing bladder muscles and increasing the bladder's capacity.
Take your tablets at the same time each day, with or without food.
It may take 4 to 6 weeks to feel the full benefits of the treatment.
Common side-effects include dry mouth, blurred vision, and constipation.
Discuss with your doctor if you have other medical conditions or are taking other medicines.
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تابع القراءة أدناه
About solifenacin
نوع الدواء | An antimuscarinic medicine |
يستخدم لـ | Symptoms of urinary urgency, frequency and incontinence |
يُعرف أيضًا باسم | Vesicare®; |
متوفر كـ | Tablets, oral liquid medicine |
Solifenacin is prescribed to treat urinary symptoms such as urgency, frequency and incontinence. Urinary urgency occurs when you have a sudden and urgent need to pass urine. If you need to take more trips to the toilet than normal, this is called urinary frequency. If you leak urine before you go to the toilet, this is called urinary incontinence.
There are several different causes of these urinary symptoms, such as weakened pelvic floor muscles, problems causing your bladder muscles to contract too much or too early, or something causing an obstruction. Sometimes the cause of these symptoms is unknown.
Solifenacin works by stopping sudden bladder muscle contractions and increasing the volume of urine that your bladder can hold. This helps to control the release of urine and eases your symptoms.
Solifenacin is also available as a combination brand (Vesomni®) with a medicine called tamsulosin for urinary urgency in men with prostate gland enlargement.
Before taking solifenacin
العودة إلى المحتوياتSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking solifenacin it is important that your doctor knows:
إذا كنت حاملاً أو مرضعة.
If you have a heart condition, such as an unusual heart rhythm, problems with the blood vessels in your heart, or heart failure.
إذا كان لديك أي مشاكل في طريقة عمل الكبد لديك، أو أي مشاكل في طريقة عمل الكلى لديك.
If you have problems with your prostate gland.
If you have any of the following conditions: increased eye pressure (called glaucoma); hiatus hernia; an overactive thyroid gland; high blood pressure; a condition causing muscle weakness, called myasthenia gravis.
If you have a condition which could cause a blockage in your stomach, bowel or urinary tract.
إذا كنت قد تعرضت في أي وقت مضى لرد فعل تحسسي تجاه دواء.
إذا كنت تتناول أي أدوية أخرى. يشمل ذلك أي أدوية تتناولها والتي يمكن شراؤها بدون وصفة طبية، بالإضافة إلى الأدوية العشبية والمكملات الغذائية.
تابع القراءة أدناه
How to take solifenacin?
العودة إلى المحتوياتBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about solifenacin and will provide you with a full list of the side-effects which you may experience from taking it.
Take the tablets exactly as your doctor tells you to. The usual dose of solifenacin is one 5 mg tablet every day, although your doctor may increase your dose to one 10 mg tablet every day if it is considered necessary.
Try to take the tablet at the same time of day each day, as this will help you to remember to take your doses regularly. You can take solifenacin either before or after meals. Swallow the tablet whole with a drink of water - do not chew or crush it before you swallow.
If you have been prescribed the oral liquid medicine, use the oral syringe to measure your dose accurately and follow the manufacturer's instructions closely. It is important to shake the bottle well, at least twenty times, before measuring each dose.
If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, leave out the missed dose but make sure you take the dose due on that day. Do not take two doses together to make up for a forgotten dose.
تحقيق أقصى استفادة من علاجك
العودة إلى المحتوياتTry to keep your regular appointments with your doctor. This is so your doctor can check on your progress and review your treatment. It may take up to 4-6 weeks before you feel the full benefit from these tablets.
Drinks containing caffeine (for example, tea, coffee, hot chocolate and cola) may make your symptoms worse. This is because caffeine is a natural diuretic and will make you want to pass urine. If you drink a lot of caffeine-containing fluids, consider switching to decaffeinated alternatives.
Try to maintain a normal life as much as possible with regard to drinking and visiting the toilet. However, drinking late at night may mean your sleep is disturbed by the desire to get up and go to the toilet, so you may want to avoid drinking too much during the evening.
Your doctor may suggest that you do some pelvic floor exercises to strengthen the muscles around the underside of your bladder. These can help to improve your symptoms.
If you buy any medicines, check with a pharmacist that they are suitable to take with solifenacin. This is because some medicines (particularly antihistamines) can increase the chance that you will experience unwanted effects such as a dry mouth, constipation and blurred vision.
تابع القراءة أدناه
Can solifenacin cause problems?
العودة إلى المحتوياتAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with solifenacin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common solifenacin side-effects (these affect more than 1 in 10 people) | ماذا يمكنني أن أفعل إذا واجهت هذا؟ |
جفاف الفم | حاول مضغ العلكة الخالية من السكر أو مص الحلويات الخالية من السكر |
Common solifenacin side-effects (these affect fewer than 1 in 10 people) | ماذا يمكنني أن أفعل إذا واجهت هذا؟ |
رؤية ضبابية | لا تقم بالقيادة ولا تستخدم الأدوات أو الآلات أثناء التأثر |
Feeling sick (nausea), indigestion, tummy (abdominal) pain, stomach discomfort | تناول وجبات بسيطة - تجنب الأطعمة الغنية أو الحارة |
الإمساك | حاول تناول نظام غذائي متوازن وشرب عدة أكواب من الماء كل يوم |
إذا شعرت بأي أعراض أخرى تعتقد أنها قد تكون بسبب الأقراص، يرجى التحدث مع طبيبك أو الصيدلي للحصول على مزيد من النصائح.
How to store solifenacin?
العودة إلى المحتوياتاحفظ جميع الأدوية بعيدًا عن متناول الأطفال وأنظارهم.
احفظه في مكان بارد وجاف، بعيدًا عن الحرارة المباشرة والضوء.
The oral liquid medicine keeps for 28 days after first opening. Discard the bottle after this time.
معلومات هامة عن جميع الأدوية
العودة إلى المحتوياتمعلومات هامة عن جميع الأدوية
لا تأخذ أبدًا أكثر من الجرعة الموصوفة. إذا كنت تشك في أنك أو شخص آخر قد تناول جرعة زائدة من هذا الدواء، اذهب إلى قسم الحوادث والطوارئ في مستشفى منطقتك. خذ العبوة معك، حتى لو كانت فارغة.
إذا كنت ستخضع لعملية جراحية أو علاج أسنان، أخبر الشخص الذي يقوم بالعلاج بالأدوية التي تتناولها.
هذا الدواء لك. لا تعطه لأشخاص آخرين حتى لو بدت حالتهم مشابهة لحالتك.
لا تحتفظ بالأدوية منتهية الصلاحية أو غير المرغوب فيها. خذها إلى صيدليتك المحلية التي ستتولى التخلص منها نيابة عنك.
إذا كان لديك أي أسئلة حول هذا الدواء، اسأل الصيدلي الخاص بك.
الإبلاغ عن الآثار الجانبية لدواء أو لقاح
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غير متأكد من خلط الأدوية؟
تحقق من التفاعلات المحتملة بين الأدوية والمكملات الغذائية والأطعمة قبل تناولها معًا.
الأسئلة الشائعة
What is the main purpose of Solifenacin?
Solifenacin is a medicine prescribed to help with urinary symptoms, specifically urgency, frequency, and incontinence. This means it helps if you have a sudden, strong need to urinate, need to go to the toilet more often than normal, or leak urine before you can get to the toilet.
How does Solifenacin work to improve urinary symptoms?
Solifenacin functions by preventing sudden contractions in your bladder muscles. It also helps your bladder hold a larger volume of urine. These actions together help you control when you release urine and reduce your symptoms.
Are there different formulations or combination options for Solifenacin?
Yes, Solifenacin is available as tablets and an oral liquid medicine. It also comes in a combination brand called Vesomni®, which includes another medicine called tamsulosin. This combination is specifically used for men who experience urinary urgency along with prostate gland enlargement.
What should I do if I forget to take a dose of Solifenacin?
If you forget a dose, take it as soon as you remember. However, if you don't remember until the next day, you should skip the missed dose and just take your regular dose for that day. It's important not to take two doses at once to compensate for a forgotten one.
Can certain drinks make my urinary symptoms worse while taking Solifenacin?
Yes, drinks that contain caffeine, such as tea, coffee, hot chocolate, and cola, can potentially worsen your symptoms. Caffeine acts as a natural diuretic, which can make you want to pass urine more often. You might consider switching to decaffeinated versions of these drinks if you consume a lot of them.
How long does it typically take to feel the full effects of Solifenacin?
It can take some time before you experience the full benefits from Solifenacin tablets. You may not feel the complete effect for up to 4 to 6 weeks after starting the treatment.
What are some common side effects I might experience with Solifenacin and how can I manage them?
A very common side effect affecting more than 1 in 10 people is a dry mouth; you can try chewing sugar-free gum or sucking sugar-free sweets to help with this. Common side effects affecting fewer than 1 in 10 people include blurred vision (in which case you should avoid driving or operating machinery), feeling sick, indigestion, or stomach discomfort (eating simple meals and avoiding rich or spicy foods can help), and constipation (eating a well-balanced diet and drinking plenty of water can be beneficial).
قراءة إضافية ومراجع
- Manufacturer's PIL, Vesicare® 5 mg and 10 mg film-coated tablets; Astellas Pharma Ltd, The electronic Medicines Compendium. Dated April 2024.
- Manufacturer's PIL, Vesicare® 1 mg/ ml oral suspension; Astellas Pharma Ltd, The electronic Medicines Compendium. Dated April 2024.
- Manufacturer's PIL, Vesomni® 6 mg/0.4 mg modified-release tablets; Astellas Pharma Ltd, The electronic Medicines Compendium. Dated April 2024.
- الأدوية كاملة BNF الطبعة 89; الجمعية الطبية البريطانية والجمعية الملكية الصيدلانية لبريطانيا العظمى، لندن.
تابع القراءة أدناه
عن المؤلفعرض السيرة الذاتية الكاملة

مايكل ستيوارت، MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
حول المراجع

سيد داجاني
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
تاريخ المقال
تمت كتابة المعلومات على هذه الصفحة ومراجعتها من قبل أطباء مؤهلين.
Next review due: 24 Aug 2027
17 Aug 2024 | أحدث إصدار

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